GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis
(2003)
Journal Article
Sturge, J., Wienke, D., East, L., Jones, G. E., & Isacke, C. M. (2003). GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis. Journal of Cell Biology, 162(5), 789-794. https://doi.org/10.1083/jcb.200302124
Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in cell guidance and chemotaxis during normal and pathological events. uPAR is GPI-anchored and the mechanism by which it transmits intracellular polarity cues... Read More about GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis.