Biological and clinical implications of nicastrin expression in invasive breast cancer

Filipovi?, Aleksandra; Gronau, Julian Hendrik; Green, Andrew R.; Wang, Jayson; Vallath, Sabari; Shao, Dongmin; Rasul, Sabeena; Ellis, Ian O.; Yagüe, Ernesto; Sturge, Justin; Coombes, R. Charles

doi:10.1007/s10549-010-0823-1

All Outputs (3)

Sphingosine kinase-1 and the collagen-binding receptor Endo180 cooperate to mediate collagen remodelling by stromal fibroblasts (2010)
Presentation / Conference Contribution
Bruche, S., Caley, M., Pshezhetskiy, D., & Sturge, J. (2010, December). Sphingosine kinase-1 and the collagen-binding receptor Endo180 cooperate to mediate collagen remodelling by stromal fibroblasts

Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation (2010)
Presentation / Conference Contribution
Nunes, J., Sauer, L., Turner, J., Waxman, J., Sturge, J., & Pshezhetskiy, D. Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation

Biological and clinical implications of nicastrin expression in invasive breast cancer (2010)
Journal Article
Filipović, A., Gronau, J. H., Green, A. R., Wang, J., Vallath, S., Shao, D., Rasul, S., Ellis, I. O., Yagüe, E., Sturge, J., & Coombes, R. C. (2011). Biological and clinical implications of nicastrin expression in invasive breast cancer. Breast cancer research and treatment, 125(1), 43-53. https://doi.org/10.1007/s10549-010-0823-1

Nicastrin is an essential component of the gamma secretase (GS) enzyme complex, required for its synthesis and recognition of substrates for proteolytic cleavage. The purpose of this study was to investigate whether nicastrin has prognostic value or... Read More about Biological and clinical implications of nicastrin expression in invasive breast cancer.