All Outputs (4)

Lipid laden macrophages in respiratory disease (2017)
Journal Article
Sadofsky, L. R., Hayman, Y. A., Hart, S. P., & Morice, A. H. (2017). Lipid laden macrophages in respiratory disease. Journal of Neurogastroenterology and Motility, 23(3), 477-478. https://doi.org/10.5056/jnm17036

Letter to the editor

Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF) (2017)
Journal Article
Vancauwenberghe, E., Noyer, L., Derouiche, S., Lemonnier, L., Gosset, P., Sadofsky, L. R., Mariot, P., Warnier, M., Bokhobza, A., Slomianny, C., Mauroy, B., Bonnal, J.-L., Dewailly, E., Delcourt, P., Allart, L., Desruelles, E., Prevarskaya, N., & Roudbaraki, M. (2017). Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF). Molecular Carcinogenesis, 56(8), 1851-1867. https://doi.org/10.1002/mc.22642

Previous studies showed the effects of resveratrol (RES) on several cancer cells, including prostate cancer (PCa) cell apoptosis without taking into consideration the impact of the tumor microenvironment (TME). The TME is composed of cancer cells, en... Read More about Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF).

The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration? (2017)
Journal Article
Hayman, Y. A., Sadofsky, L. R., Williamson, J. D., Hart, S. P., & Morice, A. H. (2017). The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration?. Ers Monograph, 3(1), 00026-2016. https://doi.org/10.1183/23120541.00026-2016

Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid laden macrophages (LLM) within the airway may indicate aspiration secondary to GOR. The proposed mechanis... Read More about The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration?.

TRPV1 polymorphisms influence capsaicin cough sensitivity in men (2017)
Journal Article
Sadofsky, L. R., Cantero-Recasens, G., Wright, C., Valverde, M. A., & Morice, A. H. (2017). TRPV1 polymorphisms influence capsaicin cough sensitivity in men. Journal of thoracic disease, 9(3), 839-840. https://doi.org/10.21037/jtd.2017.03.50

Capsaicin, the hot component of chilli peppers, is a well-known tussive agent, which is regularly used as a tool to study cough and antitussives (1). Capsaicin is known to activate the transient receptor potential vanilloid 1 (TRPV1) cation channel w... Read More about TRPV1 polymorphisms influence capsaicin cough sensitivity in men.