All Outputs (198)

A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research (2015)
Journal Article
Boland, J., Currow, D. C., Wilcock, A., Tieman, J., Hussain, J. A., Pitsillides, C., …Johnson, M. J. (2015). A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research. Journal of pain and symptom management, 49(4), 762-772. https://doi.org/10.1016/j.jpainsymman.2014.09.018

© 2015 American Academy of Hospice and Palliative Medicine. Context The challenges of palliative care clinical trial recruitment are well documented. Objectives The aim of the study was to review tested strategies to improve recruitment to trials of... Read More about A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research.

Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design (2015)
Journal Article
Campbell, R. T., Jackson, C. E., Wright, A., Gardner, R. S., Ford, I., Davidson, P. M., …McMurray, J. J. (2015). Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2(1), 25-36. https://doi.org/10.1002/ehf2.12027

Abstract Aims The primary aim of this study is to provide data to inform the design of a randomized controlled clinical trial (RCT) of a palliative care (PC) intervention in heart failure (HF). We will identify an appropriate study population with a... Read More about Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design.

Palliative care among heart failure patients in primary care: A comparison to cancer patients using english family practice data (2014)
Journal Article
Gadoud, A., Kane, E., Macleod, U., Ansell, P., Oliver, S., & Johnson, M. (2014). Palliative care among heart failure patients in primary care: A comparison to cancer patients using english family practice data. PLoS ONE, 9(11), Article e113188. https://doi.org/10.1371/journal.pone.0113188

© 2014 Gadoud et al. Introduction: Patients with heart failure have a significant symptom burden and other palliative care needs often over a longer period than patients with cancer. It is acknowledged that this need may be unmet but by how much has... Read More about Palliative care among heart failure patients in primary care: A comparison to cancer patients using english family practice data.

Clinically important differences in the intensity of chronic refractory breathlessness (2013)
Journal Article
Johnson, M. J., Bland, J. M., Oxberry, S. G., Abernethy, A. P., & Currow, D. C. (2013). Clinically important differences in the intensity of chronic refractory breathlessness. Journal of pain and symptom management, 46(6), 957-963. https://doi.org/10.1016/j.jpainsymman.2013.01.011

Context: Clinically important differences in chronic refractory breathlessness are ill defined but important in clinical practice and trial design. Objectives: To estimate the clinical relevance of differences in breathlessness intensity using distri... Read More about Clinically important differences in the intensity of chronic refractory breathlessness.

End-of-life care for non-cancer patients (2013)
Journal Article
Boland, J., & Johnson, M. J. (2013). End-of-life care for non-cancer patients. BMJ supportive & palliative care, 3(1), 2-3. https://doi.org/10.1136/bmjspcare-2013-000446

[Extract]: The origins and early development of palliative care focussed on patients with cancer, apart from sporadic developments in a few non-malignant diseases such as MND and HIV. In the UK, this has been compounded by the setting of palliative c... Read More about End-of-life care for non-cancer patients.

The ethical decisions UK doctors make regarding advanced cancer patients at the end of life - the perceived (in) appropriateness of anticoagulation for venous thromboembolism: A qualitative study (2012)
Journal Article
Sheard, L., Prout, H., Dowding, D., Noble, S., Watt, I., Maraveyas, A., & Johnson, M. (2012). The ethical decisions UK doctors make regarding advanced cancer patients at the end of life - the perceived (in) appropriateness of anticoagulation for venous thromboembolism: A qualitative study. BMC medical ethics, 13(22), Article ARTN 22. https://doi.org/10.1186/1472-6939-13-22

Background: Cancer patients are at risk of developing blood clots in their veins - venous thromboembolism (VTE) - which often takes the form of a pulmonary embolism or deep vein thrombosis. The risk increases with advanced disease. Evidence based tre... Read More about The ethical decisions UK doctors make regarding advanced cancer patients at the end of life - the perceived (in) appropriateness of anticoagulation for venous thromboembolism: A qualitative study.

Minimally clinically important difference in chronic breathlessness: every little helps (2012)
Journal Article
Oxberry, S. G., Bland, J. M., Clark, A. L., Cleland, J. G., & Johnson, M. (2012). Minimally clinically important difference in chronic breathlessness: every little helps. American Heart Journal, 164(2), 229-235. https://doi.org/10.1016/j.ahj.2012.05.003

ObjectivesThe aim of the study was to determine the minimally clinically important difference (MCID) for breathlessness due to chronic heart failure (CHF). BackgroundThe measurement of breathlessness is difficult because it is subjective and multifac... Read More about Minimally clinically important difference in chronic breathlessness: every little helps.

Diagnosis and management of people with venous thromboembolism and advanced cancer: how do doctors decide? a qualitative study (2012)
Journal Article
Johnson, M. J., Sheard, L., Maraveyas, A., Noble, S., Prout, H., Watt, I., & Dowding, D. (2012). Diagnosis and management of people with venous thromboembolism and advanced cancer: how do doctors decide? a qualitative study. BMC Medical Informatics and Decision Making, 12(75), https://doi.org/10.1186/1472-6947-12-75

Background: The treatment of cancer associated thrombosis (CAT) is well established, with level 1A evidence to support the recommendation of a low molecular weight heparin (LMWH) by daily injection for 3-6 months. However, registry data suggest compl... Read More about Diagnosis and management of people with venous thromboembolism and advanced cancer: how do doctors decide? a qualitative study.

Short-term opioids for breathlessness in stable chronic heart failure: A randomized controlled trial (2011)
Journal Article
Oxberry, S. G., Torgerson, D. J., Bland, J. M., Clark, A. L., Cleland, J. G. F., & Johnson, M. J. (2011). Short-term opioids for breathlessness in stable chronic heart failure: A randomized controlled trial. European journal of heart failure, 13(9), 1006-1012. https://doi.org/10.1093/eurjhf/hfr068

Aims To assess the effect of oral opioids vs. placebo on breathlessness in patients with chronic heart failure (CHF). Methods and results Oral morphine (Oramorph), oral oxycodone (Oxynorm), and placebo were studied in an outpatient setting. Once rand... Read More about Short-term opioids for breathlessness in stable chronic heart failure: A randomized controlled trial.

Why do health professionals refer individual patients to specialist day hospice care? (2011)
Journal Article
Bradley, S. E., Frizelle, D., & Johnson, M. (2011). Why do health professionals refer individual patients to specialist day hospice care?. Journal of palliative medicine, 14(2), 133-138. https://doi.org/10.1089/jpm.2010.0372

Background: There are no nationally agreed criteria for admission to specialist palliative day care (SPDC). Previous work has called for future research to qualitatively examine why health and social professionals make referrals to day care. Therefor... Read More about Why do health professionals refer individual patients to specialist day hospice care?.

Patients' psychosocial experiences of attending specialist palliative day care: a systematic review (2011)
Journal Article
Bradley, S. E., Frizelle, D., & Johnson, M. (2011). Patients' psychosocial experiences of attending specialist palliative day care: a systematic review. Palliative medicine, 25(3), 210-228. https://doi.org/10.1177/0269216310389222

Recent reviews conclude that the benefits of attending Specialist Palliative Day Care (SPDC) are likely to be in social, psychological and spiritual domains. However, these areas are not easily identified, leaving researchers and practitioners unclea... Read More about Patients' psychosocial experiences of attending specialist palliative day care: a systematic review.

Coping with terminal illness: The experience of attending specialist palliative day care (2010)
Journal Article
Bradley, S. E., Frizelle, D., & Johnson, M. (2010). Coping with terminal illness: The experience of attending specialist palliative day care. Journal of palliative medicine, 13(10), 1211-1218. https://doi.org/10.1089/jpm.2010.0131

Background: The provision of supportive and palliative care for people with life-shortening illness has been emphasized throughout Department of Health and National Institute of Clinical Excellence (NICE) cancer guidance. However, the question of whe... Read More about Coping with terminal illness: The experience of attending specialist palliative day care.

A randomised trial of high vs low intensity training in breathing techniques for breathless patients with malignant lung disease: A feasibility study (2010)
Journal Article
Barton, R., English, A., Nabb, S., Rigby, A. S., & Johnson, M. J. (2010). A randomised trial of high vs low intensity training in breathing techniques for breathless patients with malignant lung disease: A feasibility study. Lung Cancer, 70(3), 313-319. https://doi.org/10.1016/j.lungcan.2010.03.007

Background: Breathlessness remains a refractory symptom in malignant lung disease. Breathing training is an effective, non-pharmacological intervention but it is unclear how this should be delivered. This feasibility study aimed to assess recruitment... Read More about A randomised trial of high vs low intensity training in breathing techniques for breathless patients with malignant lung disease: A feasibility study.

Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review (2010)
Journal Article
Johnson, M. J., Oxberry, S. G., Cleland, J. G., & Clark, A. L. (2010). Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review. European journal of heart failure, 12(2), 137-147. https://doi.org/10.1093/eurjhf/hfp194

AIMS: Chronic breathlessness is a major symptom for patients with compensated chronic heart failure (CHF) and its impact is different to the breathlessness resulting from pulmonary oedema. This systematic review aims to establish which tools have bee... Read More about Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review.

Does clinical method mask significant VTE-related mortality and morbidity in malignant disease? Mini review. (2009)
Journal Article
Johnson, M., & Maraveyas, A. (2009). Does clinical method mask significant VTE-related mortality and morbidity in malignant disease? Mini review. The British Journal of Cancer, 100(12), 1837 - 1841. https://doi.org/10.1038/sj.bjc.6605091

After more than 150 years of a recognised link between cancer and vascular thromboembolic events (VTE), and despite a greatly improved understanding of its pathophysiology, epidemiology and treatment, the management of patients with cancer and VTE is... Read More about Does clinical method mask significant VTE-related mortality and morbidity in malignant disease? Mini review..

Does clinical method mask significant VTE-related mortality and morbidity in malignant disease? (2009)
Journal Article
Johnson, M., & Maraveyas, A. (2009). Does clinical method mask significant VTE-related mortality and morbidity in malignant disease?. The British Journal of Cancer, 100(12), 1837-1841. https://doi.org/10.1038/sj.bjc.6605091

After more than 150 years of a recognised link between cancer and vascular thromboembolic events (VTE), and despite a greatly improved understanding of its pathophysiology, epidemiology and treatment, the management of patients with cancer and VTE is... Read More about Does clinical method mask significant VTE-related mortality and morbidity in malignant disease?.

Venous Thromboembolism in Advanced Disease: A clinical guide (2008)
Book
Lee, A. Y. Y., Johnson, M. J., & Noble, S. I. R. (Eds.). (2008). Venous Thromboembolism in Advanced Disease: A clinical guide. Oxford: Oxford University Press. https://doi.org/10.1093/acprof%3Aoso/9780199232048.001.0001

© Oxford University Press 2009. All rights reserved. There is increasing recognition of the burden of venous thromboembolism (VTE) in patients with advanced incurable disease and the clinical, ethical, and philosophical challenges they may pose. With... Read More about Venous Thromboembolism in Advanced Disease: A clinical guide.

Management of venous thromboembolism in patients with advanced cancer: a systematic review and meta-analysis (2008)
Journal Article
Noble, S. I., Shelley, M. D., Coles, B., Williams, S. M., Wilcock, A., Johnson, M. J., & on behalf of Association for Palliative Medicine for Great Britain and Ireland. (2008). Management of venous thromboembolism in patients with advanced cancer: a systematic review and meta-analysis. The lancet oncology, 9(6), 577-584. https://doi.org/10.1016/s1470-2045%2808%2970149-9

Venous thromboembolism is common in patients with cancer. However, no management guidelines exist for venous thromboembolism specific to patients with advanced progressive cancer. To help develop recommendations for practice, we have done a comprehen... Read More about Management of venous thromboembolism in patients with advanced cancer: a systematic review and meta-analysis.