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Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design

Campbell, Ross T.; Jackson, Colette E.; Wright, Ann; Gardner, Roy S.; Ford, Ian; Davidson, Patricia M.; Denvir, Martin A.; Hogg, Karen J.; Johnson, Miriam J.; Petrie, Mark C.; McMurray, John J.V.


Ross T. Campbell

Colette E. Jackson

Ann Wright

Roy S. Gardner

Ian Ford

Patricia M. Davidson

Martin A. Denvir

Karen J. Hogg

Mark C. Petrie

John J.V. McMurray


Abstract Aims The primary aim of this study is to provide data to inform the design of a randomized controlled clinical trial (RCT) of a palliative care (PC) intervention in heart failure (HF). We will identify an appropriate study population with a high prevalence of PC needs defined using quantifiable measures. We will also identify which components a specific and targeted PC intervention in HF should include and attempt to define the most relevant trial outcomes. Methods An unselected, prospective, near-consecutive, cohort of patients admitted to hospital with acute decompensated HF will be enrolled over a 2-year period. All potential participants will be screened using B-type natriuretic peptide and echocardiography, and all those enrolled will be extensively characterized in terms of their HF status, comorbidity, and PC needs. Quantitative assessment of PC needs will include evaluation of general and disease-specific quality of life, mood, symptom burden, caregiver burden, and end of life care. Inpatient assessments will be performed and after discharge outpatient assessments will be carried out every 4 months for up to 2.5 years. Participants will be followed up for a minimum of 1 year for hospital admissions, and place and cause of death. Methods for identifying patients with HF with PC needs will be evaluated, and estimates of healthcare utilisation performed. Conclusion By assessing the prevalence of these needs, describing how these needs change over time, and evaluating how best PC needs can be identified, we will provide the foundation for designing an RCT of a PC intervention in HF.


Campbell, R. T., Jackson, C. E., Wright, A., Gardner, R. S., Ford, I., Davidson, P. M., …McMurray, J. J. (2015). Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2(1), 25-36.

Journal Article Type Article
Acceptance Date Feb 23, 2015
Online Publication Date Mar 19, 2015
Publication Date Apr 8, 2015
Deposit Date Aug 5, 2015
Publicly Available Date Nov 23, 2017
Journal ESC heart failure
Electronic ISSN 2055-5822
Publisher Wiley Open Access
Peer Reviewed Peer Reviewed
Volume 2
Issue 1
Pages 25-36
Keywords Heart failure, Palliative care
Public URL
Publisher URL
Additional Information Copy of article first published in: ESC heart failure, 2015, v.2, issue 1


Article.pdf (360 Kb)

Copyright Statement
© 2015 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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