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All Outputs (245)

ERS guideline recommendation on airflow for breathlessness: the pitfalls of applying GRADE evidence ratings to complex non-pharmacological interventions (2025)
Journal Article
Luckett, T., Swan, F., Clark, J., Roberts, M., Pearson, M., Hutchinson, A., Currow, D., Kochovska, S., Crooks, M., Smith, T., & Johnson, M. (2025). ERS guideline recommendation on airflow for breathlessness: the pitfalls of applying GRADE evidence ratings to complex non-pharmacological interventions. European respiratory journal, 65(2), Article 2402244. https://doi.org/10.1183/13993003.02244-2024

"I'm living in a 'no' world now…"-A Qualitative Study of The Widespread Impact of Living with Chronic Breathlessness, and Experiences of Identification and Assessment of this Symptom in an Older, Frail community-based Population (2025)
Journal Article
Elliott-Button, H., Johnson, M., Hutchinson, A., Currow, D., & Clark, J. (2025). "I'm living in a 'no' world now…"-A Qualitative Study of The Widespread Impact of Living with Chronic Breathlessness, and Experiences of Identification and Assessment of this Symptom in an Older, Frail community-based Population. NPJ Primary Care Respiratory Medicine, 35, Article 5. https://doi.org/10.1038/s41533-024-00409-3

Chronic breathlessness is a debilitating symptom with detrimental impact on individuals and carers. However, little is known about the experiences of community-dwelling, frail, older adults living with chronic breathlessness. To explore, (i) the psyc... Read More about "I'm living in a 'no' world now…"-A Qualitative Study of The Widespread Impact of Living with Chronic Breathlessness, and Experiences of Identification and Assessment of this Symptom in an Older, Frail community-based Population.

Barriers and facilitators for cardiopulmonary resuscitation discussions with people with heart failure (2024)
Journal Article
Barnes-Harris, M. M., Datla, S., Abel, A., Clark, A. L., & Johnson, M. J. (2024). Barriers and facilitators for cardiopulmonary resuscitation discussions with people with heart failure. PLoS ONE, 19(12), Article e0314631. https://doi.org/10.1371/journal.pone.0314631

Background Care planning with people with advanced heart failure enables appropriate care, and prevents futile interventions, such as cardio-pulmonary resuscitation (CPR). Aim To explore what motivates clinicians to conduct, and people with heart fai... Read More about Barriers and facilitators for cardiopulmonary resuscitation discussions with people with heart failure.

Breathlessness without borders: a call to action for global breathlessness research (2024)
Journal Article
Clark, J. D., Binnie, K., Bond, M., Crooks, M., Currow, D. C., Curry, J., Elsey, H., Habib, M., Hutchinson, A., Soyiri, I., Johnson, M. J., Nair, S., Rao, S., Siqueira-Filha, N., Spathis, A., & Williams, S. (2024). Breathlessness without borders: a call to action for global breathlessness research. NPJ Primary Care Respiratory Medicine, 34(1), Article 26. https://doi.org/10.1038/s41533-024-00384-9

It is likely that the burden of breathlessness in low and middle-income countries (LMICs) is much higher than has been estimated using calculations of disease burden and expected prevalence of the symptom. However, most breathlessness research has be... Read More about Breathlessness without borders: a call to action for global breathlessness research.

Practice review: Pharmacological management of severe chronic breathlessness in adults with advanced life-limiting diseases (2024)
Journal Article
Simon, S. T., Higginson, I. J., Bausewein, C., Jolley, C. J., Bajwah, S., Maddocks, M., Wilharm, C., Oluyase, A. O., & Pralong, A. (online). Practice review: Pharmacological management of severe chronic breathlessness in adults with advanced life-limiting diseases. Palliative medicine, https://doi.org/10.1177/02692163241270945

Background: Severe and refractory chronic breathlessness is a common and burdensome symptom in patients with advanced life-limiting disease. Its clinical management is challenging because of the lack of effective interventions. Aim: To provide practi... Read More about Practice review: Pharmacological management of severe chronic breathlessness in adults with advanced life-limiting diseases.

Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B) (2024)
Journal Article
Higginson, I. J., Brown, S. T., Oluyase, A. O., May, P., Maddocks, M., Costantini, M., Bajwah, S., Normand, C., Bausewein, C., Simon, S. T., Ryan, K., Currow, D. C., Johnson, M., Hart, S. P., Mather, H., Krajnik, M., Tanzi, S., Ghirotto, L., Bolton, C., Janowiak, P., …Brown, J. M. (2024). Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B). Lancet, 12(10), 763-774. https://doi.org/10.1016/S2213-2600%2824%2900187-5

Background
Breathlessness frequently becomes severe among people with respiratory disease. Mirtazapine, a widely used antidepressant, showed promise. We determined the effectiveness of mirtazapine to alleviate severe persisting breathlessness.
Meth... Read More about Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B).

Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study (2024)
Journal Article
Jackson, C., Malia, C., Zacharias, H., Dyson, J., & Johnson, M. J. (2024). Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study. PLoS ONE, 19(9), Article e0310704. https://doi.org/10.1371/journal.pone.0310704

Objectives This study seeks to understand and address barriers to practitioners’ optimal assessment and management of people with delirium in hospices. Methods Retrospective clinical record review to identify areas of low concordance with guideline-a... Read More about Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study.

Benefits of specialist palliative care by identifying active ingredients of service composition, structure, and delivery model: A systematic review with meta-analysis and meta-regression (2024)
Journal Article
Johnson, M. J., Rutterford, L., Sunny, A., Pask, S., de Wolf-Linder, S., Murtagh, F. E., & Ramsenthaler, C. (2024). Benefits of specialist palliative care by identifying active ingredients of service composition, structure, and delivery model: A systematic review with meta-analysis and meta-regression. PLoS Medicine, 21(8), Article e1004436. https://doi.org/10.1371/journal.pmed.1004436

Background AU Specialist: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly palliative care (SPC) services address the needs :of people with advanced illness. Meta-analyses to date have been challenged by heterogeneity in SPC service models an... Read More about Benefits of specialist palliative care by identifying active ingredients of service composition, structure, and delivery model: A systematic review with meta-analysis and meta-regression.

The cost of providing care by family and friends (informal care) in the last year of life: A population observational study (2024)
Journal Article
Johnson, M. J., Currow, D. C., Chynoweth, J., Weatherly, H., Keser, G., Hutchinson, A., Jones, A., Dunn, L., & Allgar, V. (2024). The cost of providing care by family and friends (informal care) in the last year of life: A population observational study. Palliative medicine, https://doi.org/10.1177/02692163241259649

Introduction: Little is known about replacement costs of care provided by informal carers during the last year of life for people dying of cancer and non-cancer diseases. Aim: To estimate informal caregiving costs and explore the relationship with ca... Read More about The cost of providing care by family and friends (informal care) in the last year of life: A population observational study.

Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction (2024)
Thesis
Patterson, M. J. Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4711450

Background: Malignant bowel obstruction (MBO) is a distressing complication of gastrointestinal, gynaecological and other cancers causing severe pain, intractable nausea and vomiting, anorexia, and death. There are no agreed best approaches for sympt... Read More about Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction.

Kinship Health Relationships: Reconfiguring the ‘good death’ in mixed species families. (2024)
Journal Article
Ashall, V., Hamilton, L., Johnson, M., & Latimer, J. (2024). Kinship Health Relationships: Reconfiguring the ‘good death’ in mixed species families. Symbolic Interaction, https://doi.org/10.1002/symb.689

Through an innovative interspecies analysis, this article explores narratives surrounding the medical treatment of humans and pet animals at the end of life among UK veterinary surgeons, medical practitioners and members of the public. Contrasting th... Read More about Kinship Health Relationships: Reconfiguring the ‘good death’ in mixed species families..

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care (2024)
Journal Article
Jackson, G. P., Jackson, C., Boland, J. W., Featherstone, I., Huang, C., Ogden, M., Sartain, K., Siddiqi, N., Twiddy, M., Pearson, M., & Johnson, M. J. (2024). Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care. Palliative medicine, 38(4), 447-456. https://doi.org/10.1177/02692163241236325

Background: Delirium is a complex condition, stressful for all involved. Although highly prevalent in palliative care settings, it remains underdiagnosed and associated with poor outcomes. Guideline-adherent delirium care may improve its detection, a... Read More about Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care.

Homecare workers needs and experiences in end of life care: rapid review (2024)
Journal Article
Forward, C., Bayley, Z., Walker, L., Krygier, J., White, C., Mwaba, K., Elliott-Button, H., Taylor, P., & Johnson, M. J. (in press). Homecare workers needs and experiences in end of life care: rapid review. BMJ Supportive & Palliative Care, https://doi.org/10.1136/spcare-2023-004737

Background Social homecare workers provide essential care to those living at home at the end of life. In the context of a service experiencing difficulties in attracting and retaining staff, we have limited knowledge about the training, support needs... Read More about Homecare workers needs and experiences in end of life care: rapid review.

Creating more comparable cohorts in observational palliative care studies: A proposed framework to improve applicability and replicability of research (2024)
Journal Article
Kochovska, S., Murtagh, F. E., Agar, M., Phillips, J. L., Dudgeon, D., Lujic, S., Johnson, M., & Currow, D. C. (2024). Creating more comparable cohorts in observational palliative care studies: A proposed framework to improve applicability and replicability of research. Palliative medicine, https://doi.org/10.1177/02692163241234227

Background: Palliative care is characterised by heterogeneous patient and caregiver populations who are provided care in different health systems and a research base including a large proportion of observational, mostly retrospective studies. The inh... Read More about Creating more comparable cohorts in observational palliative care studies: A proposed framework to improve applicability and replicability of research.

Hospital admissions in the last year of life of patients with heart failure (2024)
Journal Article
AI Abel, A., Samuel, N. A., Cuthbert, J. J., Brown, O. I., Pellicori, P., Kazmi, S., GF Cleland, J., Johnson, M., & Clark, A. L. (2024). Hospital admissions in the last year of life of patients with heart failure. European Heart Journal - Quality of Care and Clinical Outcomes, 10(2), 168-175. https://doi.org/10.1093/ehjqcco/qcad047

Aim To explore the frequency, causes, and pattern of hospitalisation for patients with chronic heart failure (HF) in the 12 months preceding death. We also investigated cause of death. Methods Patients referred to a secondary care HF clinic were rout... Read More about Hospital admissions in the last year of life of patients with heart failure.

Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making (2024)
Journal Article
Bravington, A., Boland, J. W., Greenley, S., Lind, M., Murtagh, F. E., Patterson, M., Pearson, M., & Johnson, M. J. (2024). Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making. PLoS ONE, 19(1 January), Article e0294218. https://doi.org/10.1371/journal.pone.0294218

Introduction Malignant bowel obstruction is a distressing complication of cancer, causing pain, nausea and vomiting, and often has a poor prognosis. Severe and rapidly developing symptoms, a lack of robust clinical guidelines and the need for multidi... Read More about Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making.

Ancillary hospital workers experience during COVID-19: systematic review and narrative synthesis (2024)
Journal Article
Kearsley, S. L., Walker, L., Johnson, M. J., & Bravington, A. (2024). Ancillary hospital workers experience during COVID-19: systematic review and narrative synthesis. BMJ Supportive & Palliative Care, Article spcare-2024-004855. https://doi.org/10.1136/spcare-2024-004855

Background: COVID-19 overwhelmed healthcare systems worldwide. Its impact on clinical staff is well documented, but little is known about the effects on ancillary staff (cleaners, porters and caterers). Aim: To identify the evidence of the impact of... Read More about Ancillary hospital workers experience during COVID-19: systematic review and narrative synthesis.

Erratum: Correction: Supported: Supporting, enabling, and sustaining homecare workers to deliver end-of-life care: A qualitative study protocol (PloS one (2023) 18 12 (e0291525)) (2024)
Journal Article
Bayley, Z., Bothma, J., Bravington, A., Forward, C., Hussain, J., Manthorpe, J., Pearson, M., Roberts, H., Taylor, P., Walker, L., White, C., Wray, J., & Johnson, M. J. (2024). Erratum: Correction: Supported: Supporting, enabling, and sustaining homecare workers to deliver end-of-life care: A qualitative study protocol (PloS one (2023) 18 12 (e0291525)). PLoS ONE, 19(2), Article e0298925. https://doi.org/10.1371/journal.pone.0298925

[This corrects the article DOI: 10.1371/journal.pone.0291525.].

Disability and long-term breathlessness: a cross-sectional, population study (2024)
Journal Article
Kochovska, S., Ferreira, D., Chang, S., Brunelli, V. N., Morgan, D. D., Similowski, T., Johnson, M., Ekström, M., & Currow, D. C. (2024). Disability and long-term breathlessness: a cross-sectional, population study. BMJ Open Respiratory Research, 11(1), Article e002029. https://doi.org/10.1136/bmjresp-2023-002029

Introduction: Disability, resulting from altered interactions between individuals and their environment, is a worldwide issue causing inequities and suffering. Many diseases associated with breathlessness cause disability but the relationship between... Read More about Disability and long-term breathlessness: a cross-sectional, population study.