All Outputs (2)

Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands (2015)
Journal Article
Alshehri, O. M., Montague, S., Watson, S., Carter, P., Sarker, N., Manne, B. K., Miller, J. L., Herr, A. B., Pollitt, A. Y., O'Callaghan, C. A., Kunapuli, S., Arman, M., Hughes, C. E., & Watson, S. P. (2015). Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. Biochemical Journal, 468(3), 459-473. https://doi.org/10.1042/BJ20150192

Platelets are activated by a range of stimuli that share little or no resemblance in structure to each other or to recognized ligands, including diesel exhaust particles (DEP), small peptides [4N1-1, Champs (computed helical anti-membrane proteins),... Read More about Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands.

Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis (2015)
Journal Article
Arman, M., & Krauel, K. (2015). Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis. Journal of thrombosis and haemostasis : JTH, 13(6), 893-908. https://doi.org/10.1111/jth.12905

© 2015 International Society on Thrombosis and Haemostasis. Beyond their prominent role in hemostasis and thrombosis, platelets are increasingly recognized as having immunologic functions. Supporting this, human platelets express FcγRIIA (CD32a), a l... Read More about Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis.