Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer

Macdonald, S.; Macleod, U.; Campbell, N. C.; Weller, D.; Mitchell, E.

doi:10.1038/sj.bjc.6603089

Awareness of cancer symptoms and anticipated help seeking among ethnic minority groups in England (2009)
Journal Article
Waller, J., Robb, K., Stubbings, S., Ramirez, A., Macleod, U., Austoker, J., Hiom, S., & Wardle, J. (2009). Awareness of cancer symptoms and anticipated help seeking among ethnic minority groups in England. The British Journal of Cancer, 101, S24-S30. https://doi.org/10.1038/sj.bjc.6605387

Objective:Little is known about ethnic differences in awareness of cancer-warning signs or help-seeking behaviour in Britain. As part of the National Awareness and Early Diagnosis Initiative (NAEDI), this study aimed to explore these factors as possi... Read More about Awareness of cancer symptoms and anticipated help seeking among ethnic minority groups in England.

Development of a measurement tool to assess public awareness of cancer (2009)
Journal Article
Stubbings, S., Robb, K., Waller, J., Ramirez, A., Austoker, J., Macleod, U., Hiom, S., & Wardle, J. (2009). Development of a measurement tool to assess public awareness of cancer. The British Journal of Cancer, 101, S13-S17. https://doi.org/10.1038/sj.bjc.6605385

Objective:We aimed to develop and validate a measurement tool to assess cancer awareness in the general population: the cancer awareness measure (CAM).Methods:Items assessing awareness of cancer warning signs, risk factors, incidence, screening progr... Read More about Development of a measurement tool to assess public awareness of cancer.

Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol (2009)
Journal Article
Maslekar, S., Balaji, P., Gardiner, A., Culbert, B., Monson, J. R., & Duthie, G. S. (2011). Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol. Colorectal Disease, 13(1), 48-57. https://doi.org/10.1111/j.1463-1318.2009.01988.x

Aim Propofol sedation is often associated with deep sedation and decreased manoeuvrability. Patient-maintained sedation has been used in such patients with minimal side-effects. We aimed to compare novel modified patient-maintained target-controlled... Read More about Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol.

‘Getting through' not ‘going under': a qualitative study of gender and spousal support after diagnosis with colorectal cancer (2009)
Journal Article
Emslie, C., Browne, S., MacLeod, U., Rozmovits, L., Mitchell, E., & Ziebland, S. (2009). ‘Getting through' not ‘going under': a qualitative study of gender and spousal support after diagnosis with colorectal cancer. Social science & medicine, 68(6), 1169-1175. https://doi.org/10.1016/j.socscimed.2009.01.004

Many studies have found that people with cancer value family support. Feminist work suggests that women carry most responsibility for practical and emotional support in families, but few qualitative cancer studies explicitly incorporate a gender pers... Read More about ‘Getting through' not ‘going under': a qualitative study of gender and spousal support after diagnosis with colorectal cancer.

Factors contributing to the time taken to consult with symptoms of lung cancer: A cross-sectional study (2008)
Journal Article
Smith, S. M., Campbell, N. C., MacLeod, U., Lee, A. J., Raja, A., Wyke, S., Ziebland, S. B., Duff, E. M., Ritchie, L. D., & Nicolson, M. C. (2009). Factors contributing to the time taken to consult with symptoms of lung cancer: A cross-sectional study. Thorax, 64(6), 523-531. https://doi.org/10.1136/thx.2008.096560

Objectives: To determine what factors are associated with the time people take to consult with symptoms of lung cancer, with a focus on those from rural and socially deprived areas. Methods: A cross-sectional quantitative interview survey was perform... Read More about Factors contributing to the time taken to consult with symptoms of lung cancer: A cross-sectional study.

The Irritability Questionnaire: a new scale for the measurement of irritability (2008)
Journal Article
Craig, K. J., Hietanen, H., Markova, I. S., & Berrios, G. E. (2008). The Irritability Questionnaire: a new scale for the measurement of irritability. Psychiatry research, 159(3), 367-375. https://doi.org/10.1016/j.psychres.2007.03.002

Irritability is an important symptom in patients with neuropsychiatric disorders. It is a major source of distress to patients and their carers and can lead to social and family dysfunction. Despite this, there has been little systematic research on... Read More about The Irritability Questionnaire: a new scale for the measurement of irritability.

The impact of consent on observational research: A comparison of outcomes from consenters and non consenters to an observational study (2008)
Journal Article
Macleod, U., & Watt, G. C. (2008). The impact of consent on observational research: A comparison of outcomes from consenters and non consenters to an observational study. BMC Medical Research Methodology, 8, Article 15. https://doi.org/10.1186/1471-2288-8-15

Background. Public health benefits from research often rely on the use of data from personal medical records. When neither patient consent nor anonymisation is possible, the case for accessing such records for research purposes depends on an assessme... Read More about The impact of consent on observational research: A comparison of outcomes from consenters and non consenters to an observational study.

Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systemic review (2007)
Journal Article
Mitchell, E., Weller, D., Campbell, N. C., Macdonald, S., & Macleod, U. (2008). Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systemic review. The British Journal of Cancer, 98(1), 60-70. https://doi.org/10.1038/sj.bjc.6604096

Colorectal cancer is a major global health problem, with survival varying according to stage at diagnosis. Delayed diagnosis can result from patient, practitioner or hospital delay. This paper reports the results of a review of the factors influencin... Read More about Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systemic review.

Predicting colorectal cancer risk in patients with rectal bleeding (2006)
Journal Article
Robertson, R., Campbell, C., Weller, D. P., Elton, R., Mant, D., Primrose, J., Nugent, K., Macleod, U., & Sharma, R. (2006). Predicting colorectal cancer risk in patients with rectal bleeding. The British journal of general practice : the journal of the Royal College of General Practitioners, 56(531), 763-767

Background: Rectal bleeding is an important symptom of colorectal cancer but has low predictive value in primary care. Aim: To determine which characteristics of rectal bleeding, along with other factors, are predictive of colorectal cancer. Design o... Read More about Predicting colorectal cancer risk in patients with rectal bleeding.

Investigation and treatment of faecal incontinence (2006)
Journal Article
Maslekar, S., Gardiner, A., Maklin, C., & Duthie, G. S. (2006). Investigation and treatment of faecal incontinence. Postgraduate Medical Journal, 82(968), 363-371. https://doi.org/10.1136/pgmj.2005.044099

Faecal incontinence is a debilitating condition affecting people of all ages, and significantly impairs quality of life. Proper clinical assessment followed by conservative medical therapy leads to improvement in more than 50% of cases, including pat... Read More about Investigation and treatment of faecal incontinence.

Abstracts of the AGA Institute (2006)
Journal Article
Gardiner, A., Maslekar, S., & Duthie, G. (2006). Abstracts of the AGA Institute. Gastroenterology, 130(4), A-1-A-747. https://doi.org/10.1016/s0016-5085%2806%2960008-5

Aims: Artificial neural networks (ANN) are computer programs used to identify complexrelations within data that cannot be detected with conventional linear-statistical analysis.The routine clinical predictions of need for lower gastrointestinal endos... Read More about Abstracts of the AGA Institute.

Non-medical colonoscopy (2006)
Journal Article
Maslekar, S. K., Gardiner, A., Hughes, M., & Duthie, G. S. (2006). Non-medical colonoscopy. Gastrointestinal Endoscopy, 63(5), AB114. https://doi.org/10.1016/j.gie.2006.03.148

Aims: There is increasing demand for colonoscopy especially with introduction of screening programmes. Though colonoscopy is performed by doctors and nurses, there is an acute shortage of trained colonoscopists

Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer (2006)
Journal Article
Macdonald, S., Macleod, U., Campbell, N. C., Weller, D., & Mitchell, E. (2006). Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer. The British Journal of Cancer, 94(9), 1272-1280. https://doi.org/10.1038/sj.bjc.6603089

As knowledge on the causation of cancers advances and new treatments are developed, early recognition and accurate diagnosis becomes increasingly important. This review focused on identifying factors influencing patient and primary care practitioner... Read More about Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer.

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