All Outputs (49)

Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes (2011)
Journal Article
Silversides, J. D., Smith, R., & Archibald, S. J. (2011). Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes. Dalton Transactions : an international journal of inorganic chemistry, 40(23), 6289-6297. https://doi.org/10.1039/c0dt01395a

The synthesis of chelators that form high stability complexes with copper(II) isotopes and do not suffer from transchelation in vivo has been a goal for many chemists. Such chelators will facilitate the exploitation of the Cu-64 isotope (t(1/2) = 12.... Read More about Challenges in chelating positron emitting copper isotopes: tailored synthesis of unsymmetric chelators to form ultra stable complexes.

Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2) (2011)
Journal Article
Lewis, R. A., Shahi, S. K., Laing, E., Bucca, G., Efthimiou, G., Bushell, M., & Smith, C. P. (2011). Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2). BMC research notes, 4(1), Article 78. https://doi.org/10.1186/1756-0500-4-78

Background: The present study represents a genome-wide transcriptomic analysis of the response of the model streptomycete Streptomyces coelicolor A3(2) M145 to fermentor culture in Modified Evans Media limited, respectively, for nitrogen, phosphate a... Read More about Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2).

Preparation, structural characterization, and thermal ammonolysis of two novel dimeric transition silylamide complexes (2011)
Journal Article
Cheng, F., Hope, C. N., Archibald, S. J., Bradley, J. S., Clark, S., Francesconi, M. G., …Lefebvre, F. (2011). Preparation, structural characterization, and thermal ammonolysis of two novel dimeric transition silylamide complexes. International Journal of Applied Ceramic Technology, 8(2), 467-481. https://doi.org/10.1111/j.1744-7402.2009.02452.x

The preparation and molecular structures of two novel dimeric transition metal silylamide complexes {Li0.5Zr[NHSi(NMe2)3]1.5[NSi(NMe2)3]0.5[μ -NSi(NMe2)3]}2 and {Li0.5Hf[NHSi(NMe2)3]1.5[NSi(NMe2)3]0.5[μ-NSi(NMe2)3]}2 with a tetrahedral coordination e... Read More about Preparation, structural characterization, and thermal ammonolysis of two novel dimeric transition silylamide complexes.

Effect of the VWF promoter (GT) n repeat and single-nucleotide polymorphism c.-2527G>A on circulating von Willebrand factor levels under normal conditions (2011)
Journal Article
Hickson, N., Hampshire, D., Castaman, G., Eikenboom, J., Rodeghiero, F., Peake, I., & Goodeve, A. (2011). Effect of the VWF promoter (GT) n repeat and single-nucleotide polymorphism c.-2527G>A on circulating von Willebrand factor levels under normal conditions. Journal of thrombosis and haemostasis : JTH, 9(3), 603-605. https://doi.org/10.1111/j.1538-7836.2010.04161.x

Regulation of the incorporation of tissue factor into microparticles by serine phosphorylation of the cytoplasmic domain of tissue factor (2011)
Journal Article
Collier, M. E. W., & Ettelaie, C. (2011). Regulation of the incorporation of tissue factor into microparticles by serine phosphorylation of the cytoplasmic domain of tissue factor. Journal of Biological Chemistry, 286(14), 11977-11984. https://doi.org/10.1074/jbc.m110.195214

The mechanisms that regulate the incorporation and release of tissue factors (TFs) into cell-derived microparticles are as yet unidentified. In this study, we have explored the regulation of TF release into microparticles by the phosphorylation of se... Read More about Regulation of the incorporation of tissue factor into microparticles by serine phosphorylation of the cytoplasmic domain of tissue factor.

Reversing microcrystalline tests—An analytical approach to recycling of microcrystals from drugs of abuse (2011)
Journal Article
Elie, L. E., Baron, M. G., Croxton, R. S., & Elie, M. P. (2011). Reversing microcrystalline tests—An analytical approach to recycling of microcrystals from drugs of abuse. Forensic Science International, 207(1-3), e55-e58. https://doi.org/10.1016/j.forsciint.2011.01.008

A combined analysis of microcrystalline tests followed by LC–MS or GC–MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent... Read More about Reversing microcrystalline tests—An analytical approach to recycling of microcrystals from drugs of abuse.

Low molecular weight heparin suppresses tissue factor-mediated cancer cell invasion and migration in vitro (2011)
Journal Article
Ettelaie, C., Fountain, D., Collier, M. E. W., Beeby, E., Xiao, Y. P., & Maraveyas, A. (2011). Low molecular weight heparin suppresses tissue factor-mediated cancer cell invasion and migration in vitro. Experimental and Therapeutic Medicine, 2(2), 363-367. https://doi.org/10.3892/etm.2011.211

Elevated expression of tissue factor (TF) has been associated with an increased risk of thrombosis in the majority of cancers. Moreover, treatment of cancer patients with low molecular weight heparin (LMWH) appears to have beneficial effects that rea... Read More about Low molecular weight heparin suppresses tissue factor-mediated cancer cell invasion and migration in vitro.

Axon and muscle spindle hyperplasia in the myostatin null mouse (2011)
Journal Article
Elashry, M. I., Otto, A., Matsakas, A., El-Morsy, S. E., Jones, L., Anderson, B., & Patel, K. (2011). Axon and muscle spindle hyperplasia in the myostatin null mouse. Journal of anatomy, 218(2), 173-184. https://doi.org/10.1111/j.1469-7580.2010.01327.x

Germline deletion of the myostatin gene results in hyperplasia and hypertrophy of the tension-generating (extrafusal) fibres in skeletal muscle. As this gene is expressed predominantly in myogenic tissues it offers an excellent model with which to in... Read More about Axon and muscle spindle hyperplasia in the myostatin null mouse.

Prostate cancer stem cells: do they have a basal or luminal phenotype? (2011)
Journal Article
Maitland, N. J., Frame, F. M., Polson, E. S., Lewis, J. L., & Collins, A. T. (2011). Prostate cancer stem cells: do they have a basal or luminal phenotype?. Hormones and Cancer, 2(1), 47-61. https://doi.org/10.1007/s12672-010-0058-y

The prostate is a luminal secretory tissue whose function is regulated by male sex hormones. Castration produces involution of the prostate to a reversible basal state, and as the majority of prostate cancers also have a luminal phenotype, drug-induc... Read More about Prostate cancer stem cells: do they have a basal or luminal phenotype?.