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Hyperthyroidism, and bone mineral density : dissecting the causal association with Mendelian randomization analysis (2020)
Journal Article
Deshmukh, H., Papageorgiou, M., Aye, M., England, J., Abdalla, M., & Sathyapalan, T. (in press). Hyperthyroidism, and bone mineral density : dissecting the causal association with Mendelian randomization analysis. Clinical Endocrinology, https://doi.org/10.1111/cen.14330

Introduction Untreated hyperthyroidism is associated with accelerated bone turnover, low bone mineral density (BMD) and increased susceptibility to fragility fractures. Although treatment appears to improve or even reverse some of these adverse skel... Read More about Hyperthyroidism, and bone mineral density : dissecting the causal association with Mendelian randomization analysis.

The care of older cancer patients in the United Kingdom (2020)
Journal Article
Gomes, F., Lewis, A., Morris, R., Parks, R., Kalsi, T., Babic-Illamn, G., …Simcock, R. (2020). The care of older cancer patients in the United Kingdom. ecancermedicalscience, 14, Article 1101. https://doi.org/10.3332/ECANCER.2020.1101

© 2020 the authors. The ageing population poses new challenges globally. Cancer care for older patients is one of these challenges, and it has a significant impact on societies. In the United Kingdom (UK), as the number of older cancer patients incre... Read More about The care of older cancer patients in the United Kingdom.

Alert system design based on experimental findings from long-term unobtrusive monitoring in COPD (2020)
Journal Article
den Brinker, A. C., van Dinther, R., Crooks, M. G., Thackray-Nocera, S., & Morice, A. H. (2021). Alert system design based on experimental findings from long-term unobtrusive monitoring in COPD. Biomedical Signal Processing and Control, 63, Article 102205. https://doi.org/10.1016/j.bspc.2020.102205

An observational study using a cough count monitor was executed in the home of 30 patients with Chronic Obstructive Pulmonary Disease (COPD). The monitoring system was unobtrusive, allowing long-term monitoring. This paper illustrates the cough count... Read More about Alert system design based on experimental findings from long-term unobtrusive monitoring in COPD.

Postload glucose spike but not fasting glucose determines prognosis after myocardial infarction in patients without known or newly diagnosed diabetes (2020)
Journal Article
Chattopadhyay, S., George, A., John, J., & Sathyapalan, T. (2021). Postload glucose spike but not fasting glucose determines prognosis after myocardial infarction in patients without known or newly diagnosed diabetes. Journal of Diabetes, 13(3), 191-199. https://doi.org/10.1111/1753-0407.13111

Background: The effect of postload glucose spikes (PGS), the difference between 2 hour post-load plasma glucose (2hPLPG) and fasting plasma glucose (FPG), on post–myocardial infarction (post-MI) prognosis in nondiabetic patients is unexplored. Method... Read More about Postload glucose spike but not fasting glucose determines prognosis after myocardial infarction in patients without known or newly diagnosed diabetes.

Objective Assessment of Cough: An Early Marker of Response to Biological Therapies in Asthma? (2020)
Journal Article
Faruqi, S., Sykes, D. L., Crooks, M. G., Brindle, K., Thompson, J., & Morice, A. H. (2020). Objective Assessment of Cough: An Early Marker of Response to Biological Therapies in Asthma?. Lung, 198(5), 767-770. https://doi.org/10.1007/s00408-020-00391-w

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. Cough is an important symptom of asthma. The objective assessment of chronic cough has been enhanced by the development of ambulatory cough monitoring systems. Mepolizumab has bee... Read More about Objective Assessment of Cough: An Early Marker of Response to Biological Therapies in Asthma?.

A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access (2020)
Journal Article
Eves, J., Cai, P., Latham, R., Leung, C., Carradice, D., Chetter, I., & Smith, G. (in press). A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access. The journal of vascular access, https://doi.org/10.1177/1129729820954725

Background: Arteriovenous fistulae (AVF) are preferred for dialysis access but require accurate cannulation for effective dialysis. Evidence supports improvements in cannulation and complication rates using ultrasound guidance (USG) in cannulating ot... Read More about A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access.

Virtual surgical education for core surgical trainees in the Yorkshire deanery during the COVID-19 pandemic (2020)
Journal Article
Laloo, R., Giorga, A., Williams, A., Biyani, C. S., & Yiasemidou, M. (2020). Virtual surgical education for core surgical trainees in the Yorkshire deanery during the COVID-19 pandemic. Scottish Medical Journal, 65(4), 138-143. https://doi.org/10.1177/0036933020951927

Background and Aims An online teaching programme for Core Surgical Trainees (CSTs) was designed and delivered during the COVID-19 pandemic. The aim of this study is to assess the feasibility and the reception of a fully online teaching programme.... Read More about Virtual surgical education for core surgical trainees in the Yorkshire deanery during the COVID-19 pandemic.

Role of immersive technologies in healthcare education during the COVID-19 epidemic (2020)
Journal Article
Pears, M., Yiasemidou, M., Ismail, M. A., Veneziano, D., & Biyani, C. S. (2020). Role of immersive technologies in healthcare education during the COVID-19 epidemic. Scottish Medical Journal, 65(4), 112-119. https://doi.org/10.1177/0036933020956317

The unparalleled epidemic of the novel coronavirus (COVID-19), during early December 2019 in Wuhan, China, has rapidly evolved into a global pandemic, became a matter of grave concern. The pandemic presented a unique challenge to government agencies... Read More about Role of immersive technologies in healthcare education during the COVID-19 epidemic.

Rationale and design of the LIBERATES trial: Protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction (2020)
Journal Article
Everett, C. C., Reynolds, C., Fernandez, C., Stocken, D. D., Sharples, L. D., Sathyapalan, T., …Ajjan, R. A. (2020). Rationale and design of the LIBERATES trial: Protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction. Diabetes and Vascular Disease Research, 17(5), https://doi.org/10.1177/1479164120957934

Hyperglycaemia in individuals with type 2 diabetes (T2D) and myocardial infarction (MI) is associated with guarded clinical prognosis. Studies improving glucose levels in T2D following MI relied on HbA1c as the main glycaemic marker, failing to addre... Read More about Rationale and design of the LIBERATES trial: Protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction.

Impact of chronic cough on health-related quality of life in the Korean adult general population: The Korean National Health and Nutrition Examination Survey 2010–2016 (2020)
Journal Article
Won, H., Lee, J., An, J., Sohn, K., Kang, M., Kang, S., …Song, W. (2020). Impact of chronic cough on health-related quality of life in the Korean adult general population: The Korean National Health and Nutrition Examination Survey 2010–2016. Allergy Asthma and Immunology Research, 12(6), 964-979. https://doi.org/10.4168/aair.2020.12.6.964

Purpose: Chronic cough is a prevalent condition in the community and may pose considerable impairment to quality of life (QoL). However, its disease burden remains largely undefined in the general population. The present study investigated the relati... Read More about Impact of chronic cough on health-related quality of life in the Korean adult general population: The Korean National Health and Nutrition Examination Survey 2010–2016.

Patterns of acute surgical inflammatory processes presentation of in the COVID-19 outbreak (PIACO Study): Surgery may be the best treatment option (2020)
Journal Article
Guadalajara, H., Muñoz de Nova, J. L., Fernandez Gonzalez, S., Yiasemidou, M., Recarte Rico, M., Juez, L. D., …Fuenmayor-Valera, M. L. (2020). Patterns of acute surgical inflammatory processes presentation of in the COVID-19 outbreak (PIACO Study): Surgery may be the best treatment option. British journal of surgery, 107(11), e494-e495. https://doi.org/10.1002/bjs.11950

Two-Hour Post-Load Plasma Glucose, a Biomarker to Improve the GRACE Score in Patients without Known Diabetes (2020)
Journal Article
Chattopadhyay, S., George, A., John, J., & Sathyapalan, T. (2020). Two-Hour Post-Load Plasma Glucose, a Biomarker to Improve the GRACE Score in Patients without Known Diabetes. Cardiology, 145(9), 553-561. https://doi.org/10.1159/000509180

© 2020 S. Karger AG, Basel. All rights reserved. Objective: To assess improvement in predictive performance of Global Registry of Acute Coronary Events risk score (GRS) by addition of a glucose matrix. Methods: 1,056 acute coronary syndrome (ACS) sur... Read More about Two-Hour Post-Load Plasma Glucose, a Biomarker to Improve the GRACE Score in Patients without Known Diabetes.

Obesity and Insulin Resistance: A Review of Molecular Interactions (2020)
Journal Article
Yaribeygi, H., Maleki, M., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2022). Obesity and Insulin Resistance: A Review of Molecular Interactions. Current Molecular Medicine, 21(3), 182-193. https://doi.org/10.2174/1566524020666200812221527

The prevalence of insulin resistance and diabetes mellitus is rising globally in epidemic proportions. Diabetes and its complications contribute to significant morbidity and mortality. An increase in sedentary lifestyle and consumption of a more ener... Read More about Obesity and Insulin Resistance: A Review of Molecular Interactions.

Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study (2020)
Journal Article
Long, J., Meethan, K., Arundel, C., Clarke, E., Firth, A., Sylvester, M., & Chetter, I. (2020). Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study. Journal of tissue viability, 29(4), 342-347. https://doi.org/10.1016/j.jtv.2020.07.007

Background Research nurse involvement in trials is crucial to successful conduct, however their feedback on trial design and conduct is not necessarily always collected and shared. This study was designed to explore research nurse feedback in rela... Read More about Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study.

miRNAs as a novel clinical biomarker and therapeutic targets in polycystic ovary syndrome (PCOS): A review (2020)
Journal Article
Abdalla, M., Deshmukh, H., Atkin, S. L., & Sathyapalan, T. (2020). miRNAs as a novel clinical biomarker and therapeutic targets in polycystic ovary syndrome (PCOS): A review. Life Sciences, 259, https://doi.org/10.1016/j.lfs.2020.118174

© 2020 Elsevier Inc. Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in females of the reproductive age. PCOS is commonly manifested as ovulatory dysfunction, clinical and biochemical excess androgen level, and polycystic ov... Read More about miRNAs as a novel clinical biomarker and therapeutic targets in polycystic ovary syndrome (PCOS): A review.

Corrigendum: microRNA Expression in Women With and Without Polycystic Ovarian Syndrome Matched for Body Mass Index (Frontiers in Endocrinology, (2020), 11, 10.3389/fendo.2020.00206) (2020)
Journal Article
Butler, A. E., Ramachandran, V., Sathyapalan, T., David, R., Gooderham, N. J., Benurwar, M., …Atkin, S. L. (2020). Corrigendum: microRNA Expression in Women With and Without Polycystic Ovarian Syndrome Matched for Body Mass Index (Frontiers in Endocrinology, (2020), 11, 10.3389/fendo.2020.00206). Frontiers in endocrinology, 11, Article 00515. https://doi.org/10.3389/fendo.2020.00515

Copyright © 2020 Butler, Ramachandran, Sathyapalan, David, Gooderham, Benurwar, Dargham, Hayat, Hani Najafi-Shoushtari and Atkin. An author name was incorrectly spelled as Sathypalan. The correct spelling is Sathyapalan. The authors apologize for thi... Read More about Corrigendum: microRNA Expression in Women With and Without Polycystic Ovarian Syndrome Matched for Body Mass Index (Frontiers in Endocrinology, (2020), 11, 10.3389/fendo.2020.00206).

Effect of flash glucose monitoring on glycemic control, hypoglycemia, diabetes-related distress, and resource utilization in the association of british clinical diabetologists (Abcd) nationwide audit (2020)
Journal Article
Deshmukh, H., Wilmot, E. G., Gregory, R., Barnes, D., Narendran, P., Saunders, S., …Sathyapalan, T. (2020). Effect of flash glucose monitoring on glycemic control, hypoglycemia, diabetes-related distress, and resource utilization in the association of british clinical diabetologists (Abcd) nationwide audit. Diabetes Care, 43(9), 2153-2160. https://doi.org/10.2337/dc20-0738

OBJECTIVE The FreeStyle Libre (FSL) flash glucose-monitoring device was made available on the U.K. National Health Service (NHS) drug tariff in 2017. This study aims to explore the U.K. real-world experience of FSL and the impact on glycemic control,... Read More about Effect of flash glucose monitoring on glycemic control, hypoglycemia, diabetes-related distress, and resource utilization in the association of british clinical diabetologists (Abcd) nationwide audit.

Implementation of geriatric assessment in oncology settings: A systematic realist review (2020)
Journal Article
McKenzie, G. A., Bullock, A. F., Greenley, S. L., Lind, M. J., Johnson, M. J., & Pearson, M. (2021). Implementation of geriatric assessment in oncology settings: A systematic realist review. Journal of Geriatric Oncology, 12(1), 22-33. https://doi.org/10.1016/j.jgo.2020.07.003

Older adults with cancer are more likely to have worse clinical outcomes than their younger counterparts, and shared decision-making can be difficult, due to both complexity from adverse ageing and under-representation in clinical trials. Geriatric a... Read More about Implementation of geriatric assessment in oncology settings: A systematic realist review.

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., …Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), Article e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.