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Airway reflux as a cause of respiratory disease (2013)
Journal Article
Morice, A. H. (2013). Airway reflux as a cause of respiratory disease. Breathe, 9(4), 257-266. https://doi.org/10.1183/20734735.000513

Reflux is the cause of much respiratory disease. More commonly still, it is the unrecognised agent provoking the symptoms of respiratory disease. That the reflux entering the airways from the gastrointestinal tract is central to the diagnosis, therap... Read More about Airway reflux as a cause of respiratory disease.

Symptoms of airway reflux predict exacerbations and quality of life in bronchiectasis (2013)
Journal Article
Mandal, P., Morice, A. H., Chalmers, J. D., & Hill, A. T. (2013). Symptoms of airway reflux predict exacerbations and quality of life in bronchiectasis. Respiratory medicine, 107(7), 1008-1013. https://doi.org/10.1016/j.rmed.2013.04.006

Aim We have explored the association of the upper airway symptoms related to cough with exacerbation frequency, sputum microbiology and inflammatory markers in patients with non cystic fibrosis bronchiectasis. Methods Patients with bronchiectasis com... Read More about Symptoms of airway reflux predict exacerbations and quality of life in bronchiectasis.

Chronic cough hypersensitivity syndrome (2013)
Journal Article
Morice, A. H. (2013). Chronic cough hypersensitivity syndrome. Cough, 9(1), Article 14. https://doi.org/10.1186/1745-9974-9-14

Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip, and reflux disease. A different paradigm has evolved in which cough is viewed as the primary condition characterised by afferent neuronal hypersensitivity and di... Read More about Chronic cough hypersensitivity syndrome.

Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial (2013)
Journal Article
Samuel, N., Wallace, T., Carradice, D., Mazari, F. A., & Chetter, I. C. (2013). Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial. Vascular and endovascular surgery, 47(5), 346-352. https://doi.org/10.1177/1538574413487265

Introduction: Endovenous laser ablation (EVLA) has been demonstrated to be an effective treatment for lower limb varicose veins in the short and midterm results. This study reports the 5-year outcomes of EVLA technique at different power settings. Me... Read More about Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial.

Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins (2013)
Journal Article
Samuel, N., Carradice, D., Wallace, T., Mekako, A., Hatfield, J., & Chetter, I. (2013). Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Annals of Surgery, 257(3), 419-426. https://doi.org/10.1097/SLA.0b013e318275f4e4

Introduction: No randomized clinical trial comparing treatment options for small saphenous vein (SSV) incompetence exists, and there is no clear evidence that this axis behaves the same as the great saphenous vein after treatment. This means that the... Read More about Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins.

p38 alpha phosphorylates serine 258 within the cytoplasmic domain of tissue factor and prevents its incorporation into cell-derived microparticles (2013)
Journal Article
Ettelaie, C., ElKeeb, A. M., Maraveyas, A., & Collier, M. E. W. (2013). p38 alpha phosphorylates serine 258 within the cytoplasmic domain of tissue factor and prevents its incorporation into cell-derived microparticles. BBA - Molecular Cell Research, 1833(3), 613-621. https://doi.org/10.1016/j.bbamcr.2012.11.010

We previously showed that the phosphorylation of Ser253 within the cytoplasmic domain of human tissue factor (TF) initiates the incorporation and release of this protein into cell-derived microparticles. Furthermore, subsequent phosphorylation of Ser... Read More about p38 alpha phosphorylates serine 258 within the cytoplasmic domain of tissue factor and prevents its incorporation into cell-derived microparticles.

Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair (2013)
Journal Article
Barakat, H. M., Shahin, Y., Khan, J. A., McCollum, P. T., & Chetter, I. C. (2013). Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair. World Journal of Surgery, 37(5), 1169-1173. https://doi.org/10.1007/s00268-013-1939-3

ObjectiveTo determine whether resting pre-operative left ventricular ejection fraction (LVEF) estimated by multiple gated acquisition scanning (MUGA) predicts long-term survival in patients undergoing elective abdominal aortic aneurysm (AAA) repair.... Read More about Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair.

A "Christmas tree" band for the treatment of arteriovenous dialysis access-related steal syndrome (2013)
Journal Article
Smith, G., Barnes, R., Green, L., Kuhan, G., & Chetter, I. C. (2013). A "Christmas tree" band for the treatment of arteriovenous dialysis access-related steal syndrome. Annals of vascular surgery, 27(2), 239.e9 - 239.e12. https://doi.org/10.1016/j.avsg.2012.10.004

Background Dialysis access steal syndrome (DASS) is an uncommon but often debilitating complication of dialysis access formation. We present a technical description of a novel arteriovenous fistula (AVF) banding technique for the treatment of DASS a... Read More about A "Christmas tree" band for the treatment of arteriovenous dialysis access-related steal syndrome.

Balance impairment, physical ability, and its link with disease severity in patients with intermittent claudication (2013)
Journal Article
Gohil, R. A., Mockford, K. A., Mazari, F., Khan, J., Vanicek, N., Chetter, I. C., & Coughlin, P. A. (2013). Balance impairment, physical ability, and its link with disease severity in patients with intermittent claudication. Annals of vascular surgery, 27(1), 68-74. https://doi.org/10.1016/j.avsg.2012.05.005

BackgroundTo determine whether increasing claudication severity is associated with impaired balance and physical functional ability.MethodsA prospective observational study in claudicants was performed. Disease severity was determined according to Ru... Read More about Balance impairment, physical ability, and its link with disease severity in patients with intermittent claudication.

Management of patients with chronic cough using a clinical protocol: A prospective observational study (2013)
Journal Article
Ojoo, O. C., Everett, C. F., Mulrennan, S. A., Faruqi, S., Kastelik, J. A., & Morice, A. H. (2013). Management of patients with chronic cough using a clinical protocol: A prospective observational study. Cough, 9(1), Article 2. https://doi.org/10.1186/1745-9974-9-2

Background and aims: Chronic cough is a common symptom the aetiology of which can be challenging to diagnose. Diagnostic protocols for chronic cough have required the use of specialist investigations which are not always easily available. We wanted t... Read More about Management of patients with chronic cough using a clinical protocol: A prospective observational study.

Proteomic (antibody microarray) exploration of the molecular mechanism of action of the specific COX-2 inhibitor DuP 697 (2013)
Journal Article
Agarwal, V., Hodgkinson, V. C., Eagle, G. L., Scaife, L., Lind, M. J., & Cawkwell, L. (2013). Proteomic (antibody microarray) exploration of the molecular mechanism of action of the specific COX-2 inhibitor DuP 697. International Journal of Oncology, 42(3), 1088-1092. https://doi.org/10.3892/ijo.2013.1784

We have previously shown that specific COX-2 inhibitors, including DuP 697, have anti-proliferative effects on mesothelioma cells and potentiate the cytotoxicity of pemetrexed. Here, we used a novel proteomic approach to explore the mechanism of acti... Read More about Proteomic (antibody microarray) exploration of the molecular mechanism of action of the specific COX-2 inhibitor DuP 697.