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Geriatric assessment prior to cancer treatment: a health economic evaluation   (2023)
Journal Article
Johnson, M. J., McKenzie, G. A. G., Lind, M. J., Kelly, C., & Parrott, S. (2023). Geriatric assessment prior to cancer treatment: a health economic evaluation  . Journal of Geriatric Oncology, 14(6), Article 101504. https://doi.org/10.1016/j.jgo.2023.101504

Introduction: To address uncertainty regarding the cost-effectiveness of implementing geriatric assessment (GA) in oncology practice, we undertook a synthetic, model-based economic evaluation. Materials and Methods: A decision-analytic model with emb... Read More about Geriatric assessment prior to cancer treatment: a health economic evaluation  .

Ca2+ Influx through TRPC Channels Is Regulated by Homocysteine–Copper Complexes (2023)
Journal Article
Chen, G.-L., Zeng, B., Jiang, H., Daskoulidou, N., Saurabh, R., Chitando, R. J., & Xu, S.-Z. (2023). Ca2+ Influx through TRPC Channels Is Regulated by Homocysteine–Copper Complexes. Biomolecules, 13(6), Article 952. https://doi.org/10.3390/biom13060952

An elevated level of circulating homocysteine (Hcy) has been regarded as an independent risk factor for cardiovascular disease; however, the clinical benefit of Hcy lowering-therapy is not satisfying. To explore potential unrevealed mechanisms, we in... Read More about Ca2+ Influx through TRPC Channels Is Regulated by Homocysteine–Copper Complexes.

Systematic review of women's experiences of planning home birth in consultation with maternity care providers in middle to high-income countries (2023)
Journal Article
Gillen, P., Bamidele, O., & Healy, M. (2023). Systematic review of women's experiences of planning home birth in consultation with maternity care providers in middle to high-income countries. Midwifery, 124, Article 103733. https://doi.org/10.1016/j.midw.2023.103733

Aim: To synthesise findings from published studies, which reported on women's experiences of planning a home birth in consultation with maternity care providers. Design: Systematic Review Data Sources: We searched seven bibliographic databases, (Ovid... Read More about Systematic review of women's experiences of planning home birth in consultation with maternity care providers in middle to high-income countries.

Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool (2023)
Journal Article
Goedegebuur, J., Abbel, D., Accassat, S., Achterberg, W. P., Akbari, A., Arfuch, V. M., Baddeley, E., Bax, J. J., Becker, D., Bergmeijer, B., Bertoletti, L., Blom, J. W., Calvetti, A., Cannegieter, S. C., Castro, L., Chavannes, N. H., Coma-Auli, N., Couffignal, C., Edwards, A., Edwards, M., …Noble, S. I. (2023). Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool. Thrombosis Research, 228, 54-60. https://doi.org/10.1016/j.thromres.2023.05.008

BACKGROUND: Even though antithrombotic therapy has probably little or even negative effects on the well-being of people with cancer during their last year of life, deprescribing antithrombotic therapy at the end of life is rare in practice. It is oft... Read More about Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool.

Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system (2023)
Journal Article
Barry, A., Samuel, S. F., Hosni, I., Moursi, A., Feugere, L., Sennett, C. J., Deepak, S., Achawal, S., Rajaraman, C., Iles, A., Wollenberg Valero, K. C., Scott, I. S., Green, V., Stead, L. F., Greenman, J., Wade, M. A., & Beltran-Alvarez, P. (2023). Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system. Lab on a chip, 23(11), 2664-2682. https://doi.org/10.1039/d3lc00204g

Arginine methylation is a post-translational modification that consists of the transfer of one or two methyl (CH3) groups to arginine residues in proteins. Several types of arginine methylation occur, namely monomethylation, symmetric dimethylation a... Read More about Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system.

Bringing fictional characters to life: reflections on co-creating a comic book with members of the public (2023)
Journal Article
Cairns, J. M., Roberts, H., Al-Khafaji, G., & Kwater, M. (2023). Bringing fictional characters to life: reflections on co-creating a comic book with members of the public. Research Involvement and Engagement, 9(1), Article 28. https://doi.org/10.1186/s40900-023-00437-2

There are growing calls for cancer screening to become more personalised by considering a range of risk factors, rather than a one-size-fits-all, age-based approach. The aim of this public involvement was to co-create a comic book about bowel cancer... Read More about Bringing fictional characters to life: reflections on co-creating a comic book with members of the public.

Improving asthma care through implementation of the SENTINEL programme: findings from the pilot site (2023)
Journal Article
Crooks, M. G., Crowther, L., Cummings, H., Cohen, J., Huang, C., Pitel, L., Pearson, M., Morice, A., Turgoose, J., Faruqi, S., Watt, M., Morris, T., & Xu, Y. (2023). Improving asthma care through implementation of the SENTINEL programme: findings from the pilot site. ERJ Open Research, 9(3), Article 00685-2022. https://doi.org/10.1183/23120541.00685-2022

Aim: Short-acting β2-agonist (SABA) overuse adversely impacts asthma-related outcomes and the environment. The SABA rEductioN Through ImplemeNting Hull asthma guidELines (SENTINEL) programme aims to reduce SABA overuse through supported implementatio... Read More about Improving asthma care through implementation of the SENTINEL programme: findings from the pilot site.

Metabolic and endocrine complications of long COVID-19: A review (2023)
Journal Article
Bandara, T., Deshmukh, H. A., Abdalla, M., & Sathyapalan, T. (2023). Metabolic and endocrine complications of long COVID-19: A review. Experimental and Clinical Endocrinology and Diabetes, 131(6), 367-374. https://doi.org/10.1055/a-2063-8697

Over the past two years, the COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), centralized the interest of the health care systems and the scientific world. Majority of the COVID-19 infected individuals fully r... Read More about Metabolic and endocrine complications of long COVID-19: A review.

Inferior vena cava diameter is associated with prognosis in patients with chronic heart failure independent of tricuspid regurgitation velocity (2023)
Journal Article
Iaconelli, A., Cuthbert, J., Kazmi, S., Maffia, P., Clark, A. L., Cleland, J. G., & Pellicori, P. (2023). Inferior vena cava diameter is associated with prognosis in patients with chronic heart failure independent of tricuspid regurgitation velocity. Clinical Research in Cardiology, 112(8), 1077-1086. https://doi.org/10.1007/s00392-023-02178-4

Aims: A high, Doppler-derived, tricuspid regurgitation velocity (TRV) indicates pulmonary hypertension, which may contribute to right ventricular dysfunction and worsening tricuspid regurgitation leading to systemic venous congestion, reflected by an... Read More about Inferior vena cava diameter is associated with prognosis in patients with chronic heart failure independent of tricuspid regurgitation velocity.

Use of Wearable Activity-Monitoring Technologies to Promote Physical Activity in Cancer Survivors: Challenges and Opportunities for Improved Cancer Care (2023)
Journal Article
Keats, M. R., Yu, X., Sweeney Magee, M., Forbes, C. C., Grandy, S. A., Sweeney, E., & Dummer, T. J. (2023). Use of Wearable Activity-Monitoring Technologies to Promote Physical Activity in Cancer Survivors: Challenges and Opportunities for Improved Cancer Care. International Journal of Environmental Research and Public Health, 20(6), Article 4784. https://doi.org/10.3390/ijerph20064784

The aim of this review was to explore the acceptability, opportunities, and challenges associated with wearable activity-monitoring technology to increase physical activity (PA) behavior in cancer survivors. A search of Medline, Embase, CINAHL, and S... Read More about Use of Wearable Activity-Monitoring Technologies to Promote Physical Activity in Cancer Survivors: Challenges and Opportunities for Improved Cancer Care.

Provision and delivery of survivorship care for adult patients with haematological malignancies: A scoping review protocol (2023)
Journal Article
Baldwin, Z.-A., Busby, S., Allsup, D., Cohen, J., & Bamidele, O. (2023). Provision and delivery of survivorship care for adult patients with haematological malignancies: A scoping review protocol. PLoS ONE, 18(3), Article e0282458. https://doi.org/10.1371/journal.pone.0282458

Introduction Haematological malignancies are a heterogenous group of blood and lymphatic cancers. Survivorship care is a similarly diverse term concerning patients’ health and wellbeing from diagnosis to end of life. Survivorship care for patients wi... Read More about Provision and delivery of survivorship care for adult patients with haematological malignancies: A scoping review protocol.

Women and maternity care providers experiences of planned home birth in Northern Ireland: A descriptive survey (2023)
Journal Article
Gillen, P., Bamidele, O., & Healy, M. (2023). Women and maternity care providers experiences of planned home birth in Northern Ireland: A descriptive survey. Women and Birth, 36(4), e412-e420. https://doi.org/10.1016/j.wombi.2023.01.005

Background: Where a woman gives birth impacts both her postnatal outcomes and experiences. However, for women who plan home birth in Northern Ireland, their experiences and that of their maternity care providers are rarely sought. Aim: This study exa... Read More about Women and maternity care providers experiences of planned home birth in Northern Ireland: A descriptive survey.

Is the uptake, engagement, and effectiveness of exclusively mobile interventions for the promotion of weight-related behaviors equal for all? A systematic review (2023)
Journal Article
Szinay, D., Forbes, C. C., Busse, H., DeSmet, A., Smit, E. S., & König, L. M. (in press). Is the uptake, engagement, and effectiveness of exclusively mobile interventions for the promotion of weight-related behaviors equal for all? A systematic review. Obesity Reviews, Article e13542. https://doi.org/10.1111/obr.13542

Mobile health interventions are promising behavior change tools. However, there is a concern that they may benefit some populations less than others and thus widen inequalities in health. This systematic review investigated differences in uptake of,... Read More about Is the uptake, engagement, and effectiveness of exclusively mobile interventions for the promotion of weight-related behaviors equal for all? A systematic review.

Systematic Review and Meta-Analysis of Cardiovascular Consequences of Myocardial Bridging in Hypertrophic Cardiomyopathy (2022)
Journal Article
Bruce, C., Ubhi, N., McKeegan, P., & Sanders, K. (2023). Systematic Review and Meta-Analysis of Cardiovascular Consequences of Myocardial Bridging in Hypertrophic Cardiomyopathy. The American journal of cardiology, 188, P110-P119. https://doi.org/10.1016/j.amjcard.2022.10.059

Myocardial bridging (MB) is a congenital variant in which a segment of a coronary artery follows an atypical intramural course under a “bridge” of myocardium and is notably common in hypertrophic cardiomyopathy (HCM). This systematic review and meta-... Read More about Systematic Review and Meta-Analysis of Cardiovascular Consequences of Myocardial Bridging in Hypertrophic Cardiomyopathy.

Developing and testing the ExerciseGuide UK website for people with lung cancer: reflections on the added value of patient and public involvement within a doctoral degree (2022)
Journal Article
Curry, J., Roberts, H., Smith, A., Riley, D., Pearson, M., & Forbes, C. C. (2022). Developing and testing the ExerciseGuide UK website for people with lung cancer: reflections on the added value of patient and public involvement within a doctoral degree. Research Involvement and Engagement, 8(1), Article 66. https://doi.org/10.1186/s40900-022-00395-1

Background: Lung cancer has one of the highest incidence and mortality rates worldwide. Physical activity can provide those diagnosed with lung cancer with several physical and psychological benefits. However, the examination of digitally delivered p... Read More about Developing and testing the ExerciseGuide UK website for people with lung cancer: reflections on the added value of patient and public involvement within a doctoral degree.

The negative impact of COVID-19 on working memory revealed using a rapid online quiz (2022)
Journal Article
Baseler, H. A., Aksoy, M., Salawu, A., Green, A., & Asghar, A. U. (2022). The negative impact of COVID-19 on working memory revealed using a rapid online quiz. PLoS ONE, 17(11), Article e0269353. https://doi.org/10.1371/journal.pone.0269353

Although coronavirus disease 2019 (COVID-19) affects the respiratory system, it can also have neurological consequences leading to cognitive deficits such as memory problems. The aim of our study was to assess the impact of COVID-19 on working memory... Read More about The negative impact of COVID-19 on working memory revealed using a rapid online quiz.

Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials (2022)
Journal Article
Abdalla, M. A., Shah, N., Deshmukh, H., Sahebkar, A., Östlundh, L., Al-Rifai, R. H., Atkin, S. L., & Sathyapalan, T. (2022). Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials. Therapeutic Advances in Endocrinology and Metabolism, 13, https://doi.org/10.1177/20420188221127142

Context: Polycystic ovary syndrome (PCOS) is one of the commonest endocrine disorders affecting women of reproductive age, and metformin is a widely used medication in managing this condition. Aim: To review the available literature comprehensively o... Read More about Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials.

Association between Thyroid Hormones and Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis in Obese Individuals Undergoing Bariatric Surgery (2022)
Journal Article
Ganjooei, N. A., Jamialahmadi, T., Nematy, M., Shah, N. Z., Jangjoo, S., Emami, N., Jangjoo, A., Faridnia, R., Alidadi, M., Sathyapalan, T., & Sahebkar, A. (2022). Association between Thyroid Hormones and Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis in Obese Individuals Undergoing Bariatric Surgery. Middle East Journal of Digestive Diseases, 14(4), 410-421. https://doi.org/10.34172/mejdd.2022.302

Background: Non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and hepatic fibrosis have emerged as one of the leading causes of chronic liver disease. The prevalence of the NAFLD spectrum has increased, which can be att... Read More about Association between Thyroid Hormones and Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis in Obese Individuals Undergoing Bariatric Surgery.

Time in range following flash glucose monitoring: Relationship with glycaemic control, diabetes-related distress and resource utilisation in the Association of British Clinical Diabetologists national audit (2022)
Journal Article
Deshmukh, H., Wilmot, E., Pieri, B., Choudhary, P., Shah, N., Gregory, R., Kilvert, A., Lumb, A., Christian, P., Barnes, D., Patmore, J., Walton, C., Ryder, R. E., & Sathyapalan, T. (2022). Time in range following flash glucose monitoring: Relationship with glycaemic control, diabetes-related distress and resource utilisation in the Association of British Clinical Diabetologists national audit. Diabetic medicine, Article e14942. https://doi.org/10.1111/dme.14942

Aims: The aim of this study was to understand the relationship between time in range (TIR) achieved using the isCGM with changes in glycaemic control, diabetes-related distress (DRD) and resource utilisation in people living with diabetes. Methods: C... Read More about Time in range following flash glucose monitoring: Relationship with glycaemic control, diabetes-related distress and resource utilisation in the Association of British Clinical Diabetologists national audit.