Skip to main content

Research Repository

Advanced Search

All Outputs (697)

Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis (2016)
Journal Article
Kotecha, D., Manzano, L., Krum, H., Rosano, G., Holmes, J., Altman, D. G., Collins, P. D., Packer, M., Wikstrand, J., Coats, A. J. S., Cleland, J. G. F., Kirchhof, P., von Lueder, T. G., Rigby, A. S., Andersson, B., Lip, G. Y., van Veldhuisen, D. J., Shibata, M. C., Wedel, H., Böhm, M., & Flather, M. D. (2016). Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis. BMJ, 353, i1855. https://doi.org/10.1136/bmj.i1855

© BMJ Publishing Group Ltd 2016. OBJECTIVES: To determine the efficacy and tolerability of β blockers in a broad age range of women and men with heart failure with reduced ejection fraction (HFrEF) by pooling individual patient data from placebo cont... Read More about Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis.

Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1 (2016)
Journal Article
Shoaib, A., Farag, M., Nasir, M., John, J., Gupta, S., Pellicori, P., Antony, R., Perveen, R., Rigby, A., Goode, K. M., Yassin, A., Clark, A. L., & Cleland, J. G. (2016). Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1. European journal of heart failure, 18(5), 556-563. https://doi.org/10.1002/ejhf.505

© 2016 The Authors. European Journal of Heart Failure. Aims Most studies on acute heart failure (HF) exploring the relationship between admissions to hospital for HF and subsequent outcomes have focused only on HF coded as the primary diagnosis, but... Read More about Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1.

A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study (2016)
Journal Article
Clewett, C. J., Langley, P., Bateson, A. D., Asghar, A., & Wilkinson, A. J. (2016). A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study. Health Technology Letters, 3(1), 2-5. https://doi.org/10.1049/htl.2015.0037

Hypoglycaemia unawareness is a common condition associated with increased risk of severe hypoglycaemia. The purpose of the authors' study was to develop a simple to use, home-based and non-invasive hypoglycaemia warning system based on electroencepha... Read More about A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study.

The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression (2016)
Journal Article
Jones, H. S., Gordon, A., Magwenzi, S. G., Naseem, K., Atkin, S. L., & Courts, F. L. (2016). The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression. Molecular Nutrition and Food Research, 60(4), 787-797. https://doi.org/10.1002/mnfr.201500751

Scope: Quercetin is reported to reduce blood pressure in hypertensive but not normotensive humans, but the role of endothelial redox signaling in this phenomenon has not been assessed. This study investigated the effects of physiologically obtainable... Read More about The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression.

Motivation for different types and doses of exercise during breast cancer chemotherapy: a Randomized Controlled Trial (2016)
Journal Article
Courneya, K. S., Segal, R. J., Vallerand, J. R., Forbes, C. C., Crawford, J. J., Dolan, L. B., Friedenreich, C. M., Reid, R. D., Gelmon, K., Mackey, J. R., & McKenzie, D. C. (2016). Motivation for different types and doses of exercise during breast cancer chemotherapy: a Randomized Controlled Trial. Annals of Behavioral Medicine, 50(4), 554-563. https://doi.org/10.1007/s12160-016-9782-z

Background
Exercise is beneficial for breast cancer patients during chemotherapy, but their motivation to perform different types and doses of exercise is unknown.

Purpose
The purpose of this study was to examine the anticipated and experienced... Read More about Motivation for different types and doses of exercise during breast cancer chemotherapy: a Randomized Controlled Trial.

Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people (2016)
Journal Article
Abbott, K. A., Veysey, M., Lucock, M., Niblett, S., King, K., Burrows, T., & Garg, M. L. (2016). Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people. British Journal of Nutrition, 115(8), 1379-1386. https://doi.org/10.1017/s0007114516000258

Copyright © The Authors 2016. The association between n-3 PUFA intake and type 2 diabetes (T2D) is unclear, and studies relating objective biomarkers of n-3 PUFA consumption to diabetic status remain limited. The aim of this study was to determine w... Read More about Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people.

The International Pulsar Timing Array: First data release (2016)
Journal Article
Verbiest, J. P., Lentati, L., Hobbs, G., Van Haasteren, R., Demorest, P. B., Janssen, G. H., …Zhu, X. J. (2016). The International Pulsar Timing Array: First data release. Monthly notices of the Royal Astronomical Society, 458(2), 1267-1288. https://doi.org/10.1093/mnras/stw347

The highly stable spin of neutron stars can be exploited for a variety of (astro)physical investigations. In particular, arrays of pulsars with rotational periods of the order of milliseconds can be used to detect correlated signals such as those cau... Read More about The International Pulsar Timing Array: First data release.

Expression and function of transient receptor potential channels in the female bovine reproductive tract (2016)
Journal Article
Ghavideldarestani, M., Atkin, S. L., Leese, H. J., & Sturmey, R. G. (2016). Expression and function of transient receptor potential channels in the female bovine reproductive tract. Theriogenology, 86(2), 551-561. https://doi.org/10.1016/j.theriogenology.2016.02.005

© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions. Despite this, little is known about the regulation of calcium homeostasis in the oviductal ep... Read More about Expression and function of transient receptor potential channels in the female bovine reproductive tract.

Was acupuncture developed by Han Dynasty Chinese anatomists? (2016)
Journal Article
Shaw, V., & Mclennan, A. K. (2016). Was acupuncture developed by Han Dynasty Chinese anatomists?. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 299(5), 643-659. https://doi.org/10.1002/ar.23325

Anatomical dissection has begun to reveal striking similarities between gross anatomical structures and the system of nomenclature used in traditional Chinese acupuncture. This paper argues that acupuncture point nomenclature is rooted in systematic... Read More about Was acupuncture developed by Han Dynasty Chinese anatomists?.

Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc (2016)
Journal Article
Price, T. W., Greenman, J., & Stasiuk, G. J. (2016). Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc. Dalton Transactions : an international journal of inorganic chemistry, 45(40), 15702-15724. https://doi.org/10.1039/c5dt04706d

A key part of the development of metal based Positron Emission Tomography probes is the chelation of the radiometal. In this review the recent developments in the chelation of four positron emitting radiometals, 68Ga, 64Cu, 89Zr and 44Sc, are explore... Read More about Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc.

How does rhinovirus cause the common cold cough? (2016)
Journal Article
Atkinson, S. K., Sadofsky, L. R., & Morice, A. H. (2016). How does rhinovirus cause the common cold cough?. BMJ Open Respiratory Research, 3(1), Article e000118. https://doi.org/10.1136/bmjresp-2015-000118

© 2016, BMJ Publishing Group. All rights reserved. Cough is a protective reflex to prevent aspiration and can be triggered by a multitude of stimuli. The commonest form of cough is caused by upper respiratory tract infection and has no benefit to the... Read More about How does rhinovirus cause the common cold cough?.

Children’s Spatialities: Embodiment, Emotion and Agency (2015)
Book
Seymour, J. (2015). A. Hackett, L. Procter, & J. Seymour (Eds.). Children’s Spatialities: Embodiment, Emotion and Agency. Palgrave Macmillan. https://doi.org/10.1057/9781137464989

Drawing from a wide range of disciplines, including anthropology, sociology, architecture and geography, and international contributors, this volume offers both students and scholars with an interest in the interdisciplinary study of childhood a rang... Read More about Children’s Spatialities: Embodiment, Emotion and Agency.

Feasibility and preliminary efficacy of an online intervention to increase physical activity in Nova Scotian cancer survivors: A Randomized Controlled Trial (2015)
Journal Article
Forbes, C. C., Blanchard, C. M., Mummery, W. K., & Courneya, K. S. (2015). Feasibility and preliminary efficacy of an online intervention to increase physical activity in Nova Scotian cancer survivors: A Randomized Controlled Trial. JMIR Cancer, 1(2), Article e12. https://doi.org/10.2196/cancer.4586

Background: Physical activity (PA) behavior change interventions among cancer survivors have used face-to-face, telephone, email, and print-based methods. However, computer-tailored, Internet-delivered programs may be a more viable option to achieve... Read More about Feasibility and preliminary efficacy of an online intervention to increase physical activity in Nova Scotian cancer survivors: A Randomized Controlled Trial.

Registration of supine MR mammography with breast ultrasound for surgical planning of breast conserving surgery: a feasibility study (2015)
Journal Article
Pickles, M. D., Gibbs, P., Hubbard, A., Rahman, A., Wieczorek, J., Roychaudhury, R., …Turnbull, L. W. (2017). Registration of supine MR mammography with breast ultrasound for surgical planning of breast conserving surgery: a feasibility study. Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie, 38(4), 420-426. https://doi.org/10.1055/s-0041-108008

Purpose To report the feasibility, accuracy and initial clinical experience of the use of real-time magnetic resonance navigated ultrasound (rtMRnUS) in the surgical planning of breast-conserving surgery (BCS) via guide wire insertion. Materials and... Read More about Registration of supine MR mammography with breast ultrasound for surgical planning of breast conserving surgery: a feasibility study.

Effects of exercise dose on endogenous estrogens in postmenopausal women: A randomized trial (2015)
Journal Article
Friedenreich, C. M., Neilson, H. K., Wang, Q., Stanczyk, F. Z., Yasui, Y., Duha, A., MacLaughlin, S., Kallal, C., Forbes, C. C., & Courneya, K. S. (2015). Effects of exercise dose on endogenous estrogens in postmenopausal women: A randomized trial. Endocrine-Related Cancer, 22(5), 863-876. https://doi.org/10.1530/ERC-15-0243

Exercise dose comparison trials with biomarker outcomes can identify the amount of exercise required to reduce breast cancer risk and also strengthen the causal inference between physical activity and breast cancer. The Breast Cancer and Exercise Tri... Read More about Effects of exercise dose on endogenous estrogens in postmenopausal women: A randomized trial.

Impaired glucose tolerance or newly diagnosed diabetes mellitus diagnosed during admission adversely affects prognosis after myocardial infarction: An observational study (2015)
Journal Article
George, A., Bhatia, R. T., Buchanan, G. L., Whiteside, A., Moisey, R. S., Beer, S. F., Chattopadhyay, S., Sathyapalan, T., & John, J. (2015). Impaired glucose tolerance or newly diagnosed diabetes mellitus diagnosed during admission adversely affects prognosis after myocardial infarction: An observational study. PLoS ONE, 10(11), e0142045. https://doi.org/10.1371/journal.pone.0142045

Objective To investigate the prognostic effect of newly diagnosed diabetes mellitus (NDM) and impaired glucose tolerance (IGT) post myocardial infarction (MI). Research Design and Methods Retrospective cohort study of 768 patients without preexisting... Read More about Impaired glucose tolerance or newly diagnosed diabetes mellitus diagnosed during admission adversely affects prognosis after myocardial infarction: An observational study.

Minkowski functionals: An MRI texture analysis tool for determination of the aggressiveness of breast cancer (2015)
Journal Article
Fox, M. J., Gibbs, P., & Pickles, M. D. (2016). Minkowski functionals: An MRI texture analysis tool for determination of the aggressiveness of breast cancer. Journal of magnetic resonance imaging : JMRI, 43(4), 903-910. https://doi.org/10.1002/jmri.25057

Purpose: This work aims to see whether Minkowski Functionals can be used to distinguish between cancer types before chemotherapy treatment has begun, and whether a response to treatment can be predicted by an initial scan alone. Methods: Fat-nulled T... Read More about Minkowski functionals: An MRI texture analysis tool for determination of the aggressiveness of breast cancer.