All Outputs (657)

Polycystic ovary syndrome has no independent effect on vascular, inflammatory or thrombotic markers when matched for obesity (2013)
Journal Article
Kahal, H., Aburima, A., Ungvari, T., Rigby, A. S., Dawson, A. J., Coady, A. M., Vince, R. V., Ajjan, R. A., Kilpatrick, E. S., Naseem, K. M., & Atkin, S. L. (2013). Polycystic ovary syndrome has no independent effect on vascular, inflammatory or thrombotic markers when matched for obesity. Clinical Endocrinology, 79(2), 252-258. https://doi.org/10.1111/cen.12137

Introduction Previous studies investigating cardiovascular (CV) risk in obese women with polycystic ovary syndrome (PCOS) have been potentially confounded by not adequately accounting for body weight. Objective To assess if PCOS increases CV risk ind... Read More about Polycystic ovary syndrome has no independent effect on vascular, inflammatory or thrombotic markers when matched for obesity.

Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial (2013)
Journal Article
Samuel, N., Wallace, T., Carradice, D., Mazari, F. A., & Chetter, I. C. (2013). Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial. Vascular and endovascular surgery, 47(5), 346-352. https://doi.org/10.1177/1538574413487265

Introduction: Endovenous laser ablation (EVLA) has been demonstrated to be an effective treatment for lower limb varicose veins in the short and midterm results. This study reports the 5-year outcomes of EVLA technique at different power settings. Me... Read More about Comparison of 12-W versus 14-W endovenous laser ablation in the treatment of great saphenous varicose veins: 5-year outcomes from a randomized controlled trial.

Inspiring 'The Methodological Imagination': Using art and literature in social science methods teaching (2013)
Book Chapter
Seymour, J. (2013). Inspiring 'The Methodological Imagination': Using art and literature in social science methods teaching. In M. H. Jacobsen, M. S. Drake, & A. Petersen (Eds.), Imaginative Methodologies in the Social Sciences: Creativity, Poetics and Rhetoric in Social Research. Routledge. https://doi.org/10.4324/9781315587882

This chapter shows that how the use of art and literature in undergraduate research method modules can stimulate student involvement but perhaps more importantly lead to their greater intellectual understanding of the core principles of critically re... Read More about Inspiring 'The Methodological Imagination': Using art and literature in social science methods teaching.

Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins (2013)
Journal Article
Samuel, N., Carradice, D., Wallace, T., Mekako, A., Hatfield, J., & Chetter, I. (2013). Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Annals of Surgery, 257(3), 419-426. https://doi.org/10.1097/SLA.0b013e318275f4e4

Introduction: No randomized clinical trial comparing treatment options for small saphenous vein (SSV) incompetence exists, and there is no clear evidence that this axis behaves the same as the great saphenous vein after treatment. This means that the... Read More about Randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins.

Interplay between right ventricular function and cardiac resynchronization therapy : an analysis of the CARE-HF trial (cardiac resynchronization–heart failure) (2013)
Journal Article
Damy, T., Ghio, S., Rigby, A. S., Hittinger, L., Jacobs, S., Leyva, F., Delgado, J. F., Daubert, J.-C., Gras, D., Tavazzi, L., & Cleland, J. G. (2013). Interplay between right ventricular function and cardiac resynchronization therapy : an analysis of the CARE-HF trial (cardiac resynchronization–heart failure). Journal of the American College of Cardiology, 61(21), 2153-2160. https://doi.org/10.1016/j.jacc.2013.02.049

Objectives: The aim of this study was to investigate the impact of cardiac resynchronization therapy (CRT) on right ventricular (RV) function and the influence of RV dysfunction on the echocardiographic and clinical response to CRT among patients enr... Read More about Interplay between right ventricular function and cardiac resynchronization therapy : an analysis of the CARE-HF trial (cardiac resynchronization–heart failure).

Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair (2013)
Journal Article
Barakat, H. M., Shahin, Y., Khan, J. A., McCollum, P. T., & Chetter, I. C. (2013). Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair. World Journal of Surgery, 37(5), 1169-1173. https://doi.org/10.1007/s00268-013-1939-3

ObjectiveTo determine whether resting pre-operative left ventricular ejection fraction (LVEF) estimated by multiple gated acquisition scanning (MUGA) predicts long-term survival in patients undergoing elective abdominal aortic aneurysm (AAA) repair.... Read More about Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair.

A "Christmas tree" band for the treatment of arteriovenous dialysis access-related steal syndrome (2013)
Journal Article
Smith, G., Barnes, R., Green, L., Kuhan, G., & Chetter, I. C. (2013). A "Christmas tree" band for the treatment of arteriovenous dialysis access-related steal syndrome. Annals of vascular surgery, 27(2), 239.e9 - 239.e12. https://doi.org/10.1016/j.avsg.2012.10.004

Background Dialysis access steal syndrome (DASS) is an uncommon but often debilitating complication of dialysis access formation. We present a technical description of a novel arteriovenous fistula (AVF) banding technique for the treatment of DASS a... Read More about A "Christmas tree" band for the treatment of arteriovenous dialysis access-related steal syndrome.

Initial evidence of the reliability and validity of a three-dimensional body rating scale for the congenitally blind (2013)
Journal Article
Rocha Morgado, F. F., Ferreira, M. E. C., Campana, A. N., Rigby, A. S., & Tavares, M. D. C. G. (2013). Initial evidence of the reliability and validity of a three-dimensional body rating scale for the congenitally blind. Perceptual and Motor Skills, 116(1), 91-105. https://doi.org/10.2466/24.15.27.PMS.116.1.91-105

Research on body dissatisfaction has grown significantly. However, valid and reliable instruments for measuring body dissatisfaction in the congenitally blind have yet to be developed. In three studies, we report on development, test-retest reliabili... Read More about Initial evidence of the reliability and validity of a three-dimensional body rating scale for the congenitally blind.

Management of patients with chronic cough using a clinical protocol: A prospective observational study (2013)
Journal Article
Ojoo, O. C., Everett, C. F., Mulrennan, S. A., Faruqi, S., Kastelik, J. A., & Morice, A. H. (2013). Management of patients with chronic cough using a clinical protocol: A prospective observational study. Cough, 9(1), Article 2. https://doi.org/10.1186/1745-9974-9-2

Background and aims: Chronic cough is a common symptom the aetiology of which can be challenging to diagnose. Diagnostic protocols for chronic cough have required the use of specialist investigations which are not always easily available. We wanted t... Read More about Management of patients with chronic cough using a clinical protocol: A prospective observational study.

Proteomic (antibody microarray) exploration of the molecular mechanism of action of the specific COX-2 inhibitor DuP 697 (2013)
Journal Article
Agarwal, V., Hodgkinson, V. C., Eagle, G. L., Scaife, L., Lind, M. J., & Cawkwell, L. (2013). Proteomic (antibody microarray) exploration of the molecular mechanism of action of the specific COX-2 inhibitor DuP 697. International Journal of Oncology, 42(3), 1088-1092. https://doi.org/10.3892/ijo.2013.1784

We have previously shown that specific COX-2 inhibitors, including DuP 697, have anti-proliferative effects on mesothelioma cells and potentiate the cytotoxicity of pemetrexed. Here, we used a novel proteomic approach to explore the mechanism of acti... Read More about Proteomic (antibody microarray) exploration of the molecular mechanism of action of the specific COX-2 inhibitor DuP 697.

Individual patient data meta-analysis of beta-blockers in heart failure: rationale and design (2013)
Journal Article
Kotecha, D., Manzano, L., Altman, D. G., Krum, H., Erdem, G., Williams, N., …Beta-Blockers in Heart Failure Collaborative Group. (2013). Individual patient data meta-analysis of beta-blockers in heart failure: rationale and design. Systematic reviews, 2(1), Article 7. https://doi.org/10.1186/2046-4053-2-7

The Beta-Blockers in Heart Failure Collaborative Group (BB-HF) was formed to obtain and analyze individual patient data from the major randomized controlled trials of beta-blockers in heart failure. Even though beta-blockers are an established treatm... Read More about Individual patient data meta-analysis of beta-blockers in heart failure: rationale and design.

TRPC Channels and Their Splice Variants are Essential for Promoting Human Ovarian Cancer Cell Proliferation and Tumorigenesis (2013)
Journal Article
Zeng, B., Yuan, C., Yang, X., Atkin, S. L., & Xu, S.-Z. (2013). TRPC Channels and Their Splice Variants are Essential for Promoting Human Ovarian Cancer Cell Proliferation and Tumorigenesis. Current Cancer Drug Targets, 13(1), 103-116. https://doi.org/10.2174/156800913804486629

TRPC channels are Ca2+-permeable cationic channels controlling Ca2+ influx response to the activation of G protein-coupled receptors and protein tyrosine kinase pathways or the depletion of Ca2+ stores. Here we aimed to investigate whether TRPC can a... Read More about TRPC Channels and Their Splice Variants are Essential for Promoting Human Ovarian Cancer Cell Proliferation and Tumorigenesis.

PTEN protein expression in malignant pleural mesothelioma (2012)
Journal Article
Agarwal, V., Campbell, A., Beaumont, K. L., Cawkwell, L., & Lind, M. J. (2013). PTEN protein expression in malignant pleural mesothelioma. Tumor Biology, 34(2), 847-851. https://doi.org/10.1007/s13277-012-0615-9

Malignant pleural mesothelioma is associated with poor prognosis and despite recent advances in chemotherapy, the median survival is still approximately 12 months. Loss of phosphatase and tensin homolog (PTEN) protein expression may lead to constitut... Read More about PTEN protein expression in malignant pleural mesothelioma.

Control strategies for robotic manipulators (2012)
Presentation / Conference Contribution
Khan, M. F., Ul Islam, R., & Iqbal, J. (2012). Control strategies for robotic manipulators. In 2012 International Conference on Robotics and Artificial Intelligence (ICRAI) (26-33). https://doi.org/10.1109/ICRAI.2012.6413422

This survey is aimed at presenting the major robust control strategies for rigid robot manipulators. The techniques discussed are feedback linearization/Computed torque control, Variable structure compensator, Passivity based approach and Disturbance... Read More about Control strategies for robotic manipulators.

Towards a sociology of 10–12 year olds? Emerging methodological issues in the ‘new’ social studies of childhood (2012)
Journal Article
McNamee, S., & Seymour, J. (2013). Towards a sociology of 10–12 year olds? Emerging methodological issues in the ‘new’ social studies of childhood. Childhood, 20(2), 156-168. https://doi.org/10.1177/0907568212461037

This article reports on an analysis of 320 empirical research articles published between 1993 and 2010 in three of the leading ‘childhood’ journals. The study looked to establish the potential samples used in accounts of empirical research studies wi... Read More about Towards a sociology of 10–12 year olds? Emerging methodological issues in the ‘new’ social studies of childhood.

Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis (2012)
Journal Article
Fahim, A., Crooks, M., Wilmot, R., Campbell, A. P., Morice, A., & Hart, S. (2012). Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis. Respirology : official journal of the Asian Pacific Society of Respirology, 17(8), 1247-1252. https://doi.org/10.1111/j.1440-1843.2012.02231.x

Background and objective: Idiopathic pulmonary fibrosis (IPF) is the commonest idiopathic interstitial pneumonia and carries a poor prognosis. Epidemiological evidence suggests that patients with IPF have an increased risk of developing lung cancer.... Read More about Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis.

The Vicorder device compared with SphygmoCor in the assessment of carotid-femoral pulse wave velocity in patients with peripheral arterial disease (2012)
Journal Article
Shahin, Y., Barakat, H., Barnes, R., & Chetter, I. (2013). The Vicorder device compared with SphygmoCor in the assessment of carotid-femoral pulse wave velocity in patients with peripheral arterial disease. Hypertension Research, 36(3), 208-212. https://doi.org/10.1038/hr.2012.144

To assess the reliability and reproducibility of the Vicorder's carotid-femoral pulse wave velocity (cfPWV) measurements in patients with peripheral arterial disease (PAD) and to compare between cfPWV measurements obtained using the Vicorder with tho... Read More about The Vicorder device compared with SphygmoCor in the assessment of carotid-femoral pulse wave velocity in patients with peripheral arterial disease.

Store-independent pathways for cytosolic STIM1 clustering in the regulation of store-operated Ca2+ influx (2012)
Journal Article
Zeng, B., Chen, G.-L., & Xu, S. Z. (2012). Store-independent pathways for cytosolic STIM1 clustering in the regulation of store-operated Ca2+ influx. Biochemical Pharmacology, 84(8), 1024-1035. https://doi.org/10.1016/j.bcp.2012.07.013

STIM1 is a Ca 2+ sensing molecule. Once the Ca 2+ stores are depleted, STIM1 moves towards the plasma membrane (PM) (translocation), forms puncta (clustering), and triggers store-operated Ca 2+ entry (SOCE). Although this process has been regarded as... Read More about Store-independent pathways for cytosolic STIM1 clustering in the regulation of store-operated Ca2+ influx.

Fundoplication in chronic intractable cough (2012)
Journal Article
Faruqi, S., Sedman, P., Jackson, W., Molyneux, I., & Morice, A. H. (2012). Fundoplication in chronic intractable cough. Cough, 8(1), Article 3. https://doi.org/10.1186/1745-9974-8-3

Background: Airway reflux is a common cause of chronic cough and this is often refractory to medical therapy. Surgery in the form of Nissen fundoplication has been highly successful in the treatment of the classic reflux symptoms of heartburn and dys... Read More about Fundoplication in chronic intractable cough.

MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein (2012)
Journal Article
Schenková, K., Lutz, J., Kopp, M., Ramos, S., & Rivero, F. (2012). MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein. Journal of Molecular Biology, 422(5), 659-673. https://doi.org/10.1016/j.jmb.2012.06.016

RhoBTB (BTB stands for broad-complex, tramtrack, bric à brac) proteins are tumor suppressors involved in the formation of cullin 3 (Cul3)-dependent ubiquitin ligase complexes. However, no substrates of RhoBTB-Cul3 ubiquitin ligase complexes have been... Read More about MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein.