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The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation (2018)
Journal Article
Hall, P. S., Mitchell, E. D., Smith, A. F., Cairns, D. A., Messenger, M., Hutchinson, M., Wright, J., Vinall-Collier, K., Corps, C., Hamilton, P., Meads, D., & Lewington, A. (2018). The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation. Health Technology Assessment, 22(32), 1-274. https://doi.org/10.3310/hta22320

© Queen’s Printer and Controller of HMSO 2018. Background: Acute kidney injury (AKI) is highly prevalent in hospital inpatient populations, leading to significant mortality and morbidity, reduced quality of life and high short- and long-term health-c... Read More about The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation.

Improving predictive asthma algorithms with modelled environment data for Scotland: an observational cohort study protocol (2018)
Journal Article
Soyiri, I. N., Sheikh, A., Reis, S., Kavanagh, K., Vieno, M., Clemens, T., Carnell, E. J., Pan, J., King, A., Beck, R. C., Ward, H. J., Dibben, C., Robertson, C., & Simpson, C. R. (2018). Improving predictive asthma algorithms with modelled environment data for Scotland: an observational cohort study protocol. BMJ open, 8(5), Article e023289. https://doi.org/10.1136/bmjopen-2018-023289

Abstract Introduction Asthma has a considerable, but potentially, avoidable burden on many populations globally. Scotland has some of the poorest health outcomes from asthma. Although ambient pollution, weather changes and sociodemographic factors ha... Read More about Improving predictive asthma algorithms with modelled environment data for Scotland: an observational cohort study protocol.

Validation of the dyspnea exertion scale of breathlessness in people with life-limiting illness (2018)
Journal Article
Sandberg, J., Johnson, M. J., Currow, D. C., & Ekström, M. (2018). Validation of the dyspnea exertion scale of breathlessness in people with life-limiting illness. Journal of pain and symptom management, 56(3), 430-435.e2. https://doi.org/10.1016/j.jpainsymman.2018.05.002

Background Although chronic breathlessness is common in life-limiting illnesses, validated feasible instruments to measure functional impact of the symptom in this population are scarce. We aimed to validate the Dyspnea Exertion Scale (DES) compared... Read More about Validation of the dyspnea exertion scale of breathlessness in people with life-limiting illness.

A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment (2018)
Journal Article
Hardy, J., Skerman, H., Glare, P., Philip, J., Hudson, P., Mitchell, G., Martin, P., Spruyt, O., Currow, D., & Yates, P. (2018). A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment. BMC Cancer, 18(1), Article 510. https://doi.org/10.1186/s12885-018-4404-8

© 2018 The Author(s). Background: Nausea/vomiting (N/V) not related to anti-cancer treatment is common in patients with advanced cancer. The standard approach to management is to define a dominant cause, and treat with an antiemetic selected through... Read More about A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment.

Self-reported skin concerns: An epidemiological study of community-dwelling older people (2018)
Journal Article
Cowdell, F., Dyson, J., Long, J., & Macleod, U. (2018). Self-reported skin concerns: An epidemiological study of community-dwelling older people. International journal of older people nursing, 13(3), e12195. https://doi.org/10.1111/opn.12195

Background Globally the population is getting older and it is essential to develop effective interventions to promote healthy ageing. Skin change with age is inevitable and renders this often neglected organ more vulnerable to damage and breakdown;... Read More about Self-reported skin concerns: An epidemiological study of community-dwelling older people.

Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy (2018)
Journal Article
Sadeghi, M. H., Wright, C. E., Hart, S., Crooks, M., & Morice, A. (2018). Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy. Annals of Allergy, Asthma and Immunology, 120(3), 285-291. https://doi.org/10.1016/j.anai.2017.12.004

© 2017 Background: Whether the fraction of exhaled nitric oxide (FeNO) measurement can predict the response to anti-inflammatory treatment in chronic cough is unknown. Objective: To explore whether the effectiveness of treatment with 10 mg of montelu... Read More about Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy.

Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial (2018)
Journal Article
Gurusamy, K., Corrigan, N., Croft, J., Twiddy, M., Morris, S., Woodward, N., Bandula, S., Hochhauser, D., Napp, V., Pullan, A., Jakowiw, N., Prasad, R., Damink, S. O., van Laarhoven, C. J., de Wilt, J. H., Brown, J., & Davidson, B. R. (2018). Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial. Trials, 19(1), https://doi.org/10.1186/s13063-018-2499-5

Background:Although surgical resection has been considered the only curative option for colorectal livermetastases (CLM), thermal ablation has recently been suggested as an alternative curative treatment. A prospective randomised trial is required to... Read More about Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial.

Is cough important in acute exacerbations of COPD? (2018)
Journal Article
Crooks, M. G., Brown, T., & Morice, A. H. (2018). Is cough important in acute exacerbations of COPD?. Respiratory Physiology and Neurobiology, 257, 30-35. https://doi.org/10.1016/j.resp.2018.02.005

Chronic obstructive pulmonary disease is predicted to become the 4th leading cause of death worldwide by 2030. The natural history of the disease includes progressive symptoms punctuated by acute exacerbations during which symptoms rapidly deteriorat... Read More about Is cough important in acute exacerbations of COPD?.

Feasibility of a multicentre, randomised controlled trial of laparoscopic versus open colorectal surgery in the acute setting: The LaCeS feasibility trial protocol (2018)
Journal Article
Harji, D., Marshall, H., Gordon, K., Crow, H., Hiley, V., Burke, D., Griffiths, B., Moriarty, C., Twiddy, M., O'Dwyer, J., Verjee, A., Brown, J., & Sagar, P. (2018). Feasibility of a multicentre, randomised controlled trial of laparoscopic versus open colorectal surgery in the acute setting: The LaCeS feasibility trial protocol. BMJ open, 8(2), Article e018618. https://doi.org/10.1136/bmjopen-2017-018618

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. Introduction Acute colorectal surgery forms a significant prop... Read More about Feasibility of a multicentre, randomised controlled trial of laparoscopic versus open colorectal surgery in the acute setting: The LaCeS feasibility trial protocol.

Poor glycaemic control and its metabolic and demographic risk factors in a Malaysian community-based study (2018)
Journal Article
Reidpath, D. D., Soyiri, I., Jahan, N. K., Mohan, D., Ahmad, B., Ahmad, M. P., Kassim, Z. B., & Allotey, P. (2018). Poor glycaemic control and its metabolic and demographic risk factors in a Malaysian community-based study. International Journal of Public Health, 63(2), 193-202. https://doi.org/10.1007/s00038-017-1072-4

Objectives The lack of population-based evidence on the risk factors for poor glycaemic control in diabetics, particularly in resource-poor settings, is a challenge for the prevention of long-term complications. This study aimed to identify the metab... Read More about Poor glycaemic control and its metabolic and demographic risk factors in a Malaysian community-based study.

A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement (2018)
Journal Article
Twiddy, M., Czoski Murray, C. J., Mason, S. J., Meads, D., Wright, J. M., Mitchell, E. D., & Minton, J. (2018). A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement. BMJ open, 8(1), e019099. https://doi.org/10.1136/bmjopen-2017-019099

Abstract Objective Outpatient parenteral antimicrobial therapy (OPAT) provides opportunities for improved cost savings, but in the UK, implementation is patchy and a variety of service models are in use. The slow uptake in the UK and Europe is due to... Read More about A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement.

The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an on-road driving task: A systematic review (2018)
Journal Article
Ferreira, D. H., Boland, J. W., Phillips, J. L., Lam, L., & Currow, D. C. (2018). The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an on-road driving task: A systematic review. Palliative medicine, 32(4), 786-803. https://doi.org/10.1177/0269216317746583

Background: Driving cessation is associated with poor health-related outcomes. People with chronic diseases are often prescribed long-term opioid agonists that have the potential to impair driving. Studies evaluating the impact of opioids on driving-... Read More about The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an on-road driving task: A systematic review.

Prevalence of chronic obstructive pulmonary disease (COPD) in China in 1990 and 2010 (2017)
Journal Article
Chan, K. Y., Li, X., Chen, W., Song, P., Wong, N. W. K., Poon, A. N., Jian, W., Soyiri, I. N., Cousens, S., Adeloye, D., Sheikh, A., Campbell, H., & Rudan, I. (2017). Prevalence of chronic obstructive pulmonary disease (COPD) in China in 1990 and 2010. Journal of Global Health, 7(2), Article 020704. https://doi.org/10.7189/jogh.07.020704

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is set to become the third most frequent cause of death and also the third largest cause of global morbidity by 2020. In China, where the population is aging rapidly, COPD has become one of the... Read More about Prevalence of chronic obstructive pulmonary disease (COPD) in China in 1990 and 2010.

One evidence base; three stories: do opioids relieve chronic breathlessness? (2017)
Journal Article
Ekstrom, M., Currow, D. C., Johnson, M. J., Ekström, M., Bajwah, S., Bland, J. M., Currow, D., Hussain, J., & Johnson, M. (2018). One evidence base; three stories: do opioids relieve chronic breathlessness?. Thorax, 73(1), 88-90. https://doi.org/10.1136/thoraxjnl-2016-209868

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/. The efficacy of low-dose systemic opioids for chronic br... Read More about One evidence base; three stories: do opioids relieve chronic breathlessness?.

Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study (2017)
Journal Article
Luckett, T., Phillips, J., Johnson, M., Garcia, M., Bhattarai, P., Carrieri-Kohlman, V., Hutchinson, A., Disler, R. T., Currow, D., Agar, M., Ivynian, S., Chye, R., Newton, P. J., & Davidson, P. M. (2017). Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study. BMJ open, 7(12), e017536. https://doi.org/10.1136/bmjopen-2017-017536

Objectives Breathlessness ‘crises’ in people with chronic respiratory conditions are a common precipitant for emergency department (ED) presentations, many of which might be avoided through improved self-management and support. This study sought insi... Read More about Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study.