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All Outputs (358)

Determinants of physiological uptake of 18F-fluorodeoxyglucose in palatine tonsils (2018)
Journal Article
Birkin, E., Moore, K. S., Huang, C., Christopher, M., Rees, J. I., Jayaprakasam, V., & Fielding, P. A. (2018). Determinants of physiological uptake of 18F-fluorodeoxyglucose in palatine tonsils. Medicine, 97(24), Article e11040. https://doi.org/10.1097/md.0000000000011040

To determine the extent of physiological variation of uptake of 18F-flurodeoxyglucose (FDG) within palatine tonsils. To define normal limits for side-to-side variation and characterize factors affecting tonsillar uptake of FDG.

Over a period of 16... Read More about Determinants of physiological uptake of 18F-fluorodeoxyglucose in palatine tonsils.

Exogenous sex steroid hormones and asthma in females: protocol for a population-based retrospective cohort study using a UK primary care database (2018)
Journal Article
Nwaru, B. I., Simpson, C. R., Soyiri, I. N., Pillinger, R., Appiagyei, F., Ryan, D., Critchley, H., Price, D. B., Hawrylowicz, C. M., & Sheikh, A. (2018). Exogenous sex steroid hormones and asthma in females: protocol for a population-based retrospective cohort study using a UK primary care database. BMJ open, 8(6), Article e020075. https://doi.org/10.1136/bmjopen-2017-020075

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Female sex steroid hormones have been implicated in sex-related differences in the development... Read More about Exogenous sex steroid hormones and asthma in females: protocol for a population-based retrospective cohort study using a UK primary care database.

Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016 (2018)
Journal Article
Fullman, N., Yearwood, J., Abay, S. M., Abbafati, C., Abd-Allah, F., Abdela, J., Abdelalim, A., Abebe, Z., Abebo, T. A., Aboyans, V., Abraha, H. N., Abreu, D. M. X., Abu-Raddad, L. J., Adane, A. A., Adedoyin, R. A., Adetokunboh, O., Adhikari, T. B., Afarideh, M., Afshin, A., Agarwal, G., …Lozano, R. (2018). Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016. Lancet, 391(10136), 2236-2271. https://doi.org/10.1016/S0140-6736%2818%2930994-2

Copyright © 2018 The Author(s). Published by Elsevier Ltd. Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has falt... Read More about Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016.

The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation (2018)
Journal Article
Hall, P. S., Mitchell, E. D., Smith, A. F., Cairns, D. A., Messenger, M., Hutchinson, M., Wright, J., Vinall-Collier, K., Corps, C., Hamilton, P., Meads, D., & Lewington, A. (2018). The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation. Health Technology Assessment, 22(32), 1-274. https://doi.org/10.3310/hta22320

© Queen’s Printer and Controller of HMSO 2018. Background: Acute kidney injury (AKI) is highly prevalent in hospital inpatient populations, leading to significant mortality and morbidity, reduced quality of life and high short- and long-term health-c... Read More about The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation.

Improving predictive asthma algorithms with modelled environment data for Scotland: an observational cohort study protocol (2018)
Journal Article
Soyiri, I. N., Sheikh, A., Reis, S., Kavanagh, K., Vieno, M., Clemens, T., Carnell, E. J., Pan, J., King, A., Beck, R. C., Ward, H. J., Dibben, C., Robertson, C., & Simpson, C. R. (2018). Improving predictive asthma algorithms with modelled environment data for Scotland: an observational cohort study protocol. BMJ open, 8(5), Article e023289. https://doi.org/10.1136/bmjopen-2018-023289

Abstract
Introduction Asthma has a considerable, but potentially, avoidable burden on many populations globally. Scotland has some of the poorest health outcomes from asthma. Although ambient pollution, weather changes and sociodemographic factors ha... Read More about Improving predictive asthma algorithms with modelled environment data for Scotland: an observational cohort study protocol.

Validation of the dyspnea exertion scale of breathlessness in people with life-limiting illness (2018)
Journal Article
Sandberg, J., Johnson, M. J., Currow, D. C., & Ekström, M. (2018). Validation of the dyspnea exertion scale of breathlessness in people with life-limiting illness. Journal of pain and symptom management, 56(3), 430-435.e2. https://doi.org/10.1016/j.jpainsymman.2018.05.002

Background
Although chronic breathlessness is common in life-limiting illnesses, validated feasible instruments to measure functional impact of the symptom in this population are scarce. We aimed to validate the Dyspnea Exertion Scale (DES) compared... Read More about Validation of the dyspnea exertion scale of breathlessness in people with life-limiting illness.

A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment (2018)
Journal Article
Hardy, J., Skerman, H., Glare, P., Philip, J., Hudson, P., Mitchell, G., Martin, P., Spruyt, O., Currow, D., & Yates, P. (2018). A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment. BMC Cancer, 18(1), Article 510. https://doi.org/10.1186/s12885-018-4404-8

© 2018 The Author(s). Background: Nausea/vomiting (N/V) not related to anti-cancer treatment is common in patients with advanced cancer. The standard approach to management is to define a dominant cause, and treat with an antiemetic selected through... Read More about A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment.

Self-reported skin concerns: An epidemiological study of community-dwelling older people (2018)
Journal Article
Cowdell, F., Dyson, J., Long, J., & Macleod, U. (2018). Self-reported skin concerns: An epidemiological study of community-dwelling older people. International journal of older people nursing, 13(3), e12195. https://doi.org/10.1111/opn.12195

Background
Globally the population is getting older and it is essential to develop effective interventions to promote healthy ageing. Skin change with age is inevitable and renders this often neglected organ more vulnerable to damage and breakdown;... Read More about Self-reported skin concerns: An epidemiological study of community-dwelling older people.

Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy (2018)
Journal Article
Sadeghi, M. H., Wright, C. E., Hart, S., Crooks, M., & Morice, A. (2018). Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy. Annals of Allergy, Asthma and Immunology, 120(3), 285-291. https://doi.org/10.1016/j.anai.2017.12.004

© 2017 Background: Whether the fraction of exhaled nitric oxide (FeNO) measurement can predict the response to anti-inflammatory treatment in chronic cough is unknown. Objective: To explore whether the effectiveness of treatment with 10 mg of montelu... Read More about Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy.

Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial (2018)
Journal Article
Gurusamy, K., Corrigan, N., Croft, J., Twiddy, M., Morris, S., Woodward, N., Bandula, S., Hochhauser, D., Napp, V., Pullan, A., Jakowiw, N., Prasad, R., Damink, S. O., van Laarhoven, C. J., de Wilt, J. H., Brown, J., & Davidson, B. R. (2018). Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial. Trials, 19(1), https://doi.org/10.1186/s13063-018-2499-5

Background:Although surgical resection has been considered the only curative option for colorectal livermetastases (CLM), thermal ablation has recently been suggested as an alternative curative treatment. A prospective randomised trial is required to... Read More about Liver resection surgery versus thermal ablation for colorectal LiVer MetAstases (LAVA): study protocol for a randomised controlled trial.

Is cough important in acute exacerbations of COPD? (2018)
Journal Article
Crooks, M. G., Brown, T., & Morice, A. H. (2018). Is cough important in acute exacerbations of COPD?. Respiratory Physiology and Neurobiology, 257, 30-35. https://doi.org/10.1016/j.resp.2018.02.005

Chronic obstructive pulmonary disease is predicted to become the 4th leading cause of death worldwide by 2030. The natural history of the disease includes progressive symptoms punctuated by acute exacerbations during which symptoms rapidly deteriorat... Read More about Is cough important in acute exacerbations of COPD?.

Feasibility of a multicentre, randomised controlled trial of laparoscopic versus open colorectal surgery in the acute setting: The LaCeS feasibility trial protocol (2018)
Journal Article
Harji, D., Marshall, H., Gordon, K., Crow, H., Hiley, V., Burke, D., Griffiths, B., Moriarty, C., Twiddy, M., O'Dwyer, J., Verjee, A., Brown, J., & Sagar, P. (2018). Feasibility of a multicentre, randomised controlled trial of laparoscopic versus open colorectal surgery in the acute setting: The LaCeS feasibility trial protocol. BMJ open, 8(2), Article e018618. https://doi.org/10.1136/bmjopen-2017-018618

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. Introduction Acute colorectal surgery forms a significant prop... Read More about Feasibility of a multicentre, randomised controlled trial of laparoscopic versus open colorectal surgery in the acute setting: The LaCeS feasibility trial protocol.

Poor glycaemic control and its metabolic and demographic risk factors in a Malaysian community-based study (2018)
Journal Article
Reidpath, D. D., Soyiri, I., Jahan, N. K., Mohan, D., Ahmad, B., Ahmad, M. P., Kassim, Z. B., & Allotey, P. (2018). Poor glycaemic control and its metabolic and demographic risk factors in a Malaysian community-based study. International Journal of Public Health, 63(2), 193-202. https://doi.org/10.1007/s00038-017-1072-4

Objectives
The lack of population-based evidence on the risk factors for poor glycaemic control in diabetics, particularly in resource-poor settings, is a challenge for the prevention of long-term complications. This study aimed to identify the metab... Read More about Poor glycaemic control and its metabolic and demographic risk factors in a Malaysian community-based study.

A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement (2018)
Journal Article
Twiddy, M., Czoski Murray, C. J., Mason, S. J., Meads, D., Wright, J. M., Mitchell, E. D., & Minton, J. (2018). A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement. BMJ open, 8(1), e019099. https://doi.org/10.1136/bmjopen-2017-019099

Abstract
Objective Outpatient parenteral antimicrobial therapy (OPAT) provides opportunities for improved cost savings, but in the UK, implementation is patchy and a variety of service models are in use. The slow uptake in the UK and Europe is due to... Read More about A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement.

The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an on-road driving task: A systematic review (2018)
Journal Article
Ferreira, D. H., Boland, J. W., Phillips, J. L., Lam, L., & Currow, D. C. (2018). The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an on-road driving task: A systematic review. Palliative medicine, 32(4), 786-803. https://doi.org/10.1177/0269216317746583

Background: Driving cessation is associated with poor health-related outcomes. People with chronic diseases are often prescribed long-term opioid agonists that have the potential to impair driving. Studies evaluating the impact of opioids on driving-... Read More about The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an on-road driving task: A systematic review.