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All Outputs (54)

Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis (2017)
Journal Article
Boland, J. W., Allgar, V., Boland, E. G., Oviasu, O., Agar, M., Currow, D. C., & Johnson, M. J. (2017). Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis. Journal of palliative medicine, 20(11), 1274-1279. https://doi.org/10.1089/jpm.2017.0129

Background: Medications for symptom management in palliative care have associated, but poorly understood, harms. Drug-related harms have important clinical implications, may impact on patients’ compliance and contribute to symptoms. Objective: To exp... Read More about Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis.

Somatostatin analogues compared to placebo and other pharmacological agents in the management of symptoms of inoperable malignant bowel obstruction: a systematic review (2016)
Journal Article
Obita, G. P., Boland, E. G., Currow, D. C., Johnson, M. J., & Boland, J. W. (2016). Somatostatin analogues compared to placebo and other pharmacological agents in the management of symptoms of inoperable malignant bowel obstruction: a systematic review. Journal of pain and symptom management, 52(6), 901-919. https://doi.org/10.1016/j.jpainsymman.2016.05.032

Context Somatostatin analogues are commonly used to relieve symptoms in malignant bowel obstruction (MBO) but are more expensive than other antisecretory agents. Objectives To evaluate the evidence of effectiveness of somatostatin analogues compared... Read More about Somatostatin analogues compared to placebo and other pharmacological agents in the management of symptoms of inoperable malignant bowel obstruction: a systematic review.

Clinically relevant concentrations of opioids for in vitro studies (2016)
Journal Article
Boland, J. W., & Pockley, A. G. (2016). Clinically relevant concentrations of opioids for in vitro studies. Journal of Opioid Management, 12(5), 313-321. https://doi.org/10.5055/jom.2016.0348

© 2016 Journal of Opioid Management, All Rights Reserved. Objectives: Numerous in vitro studies have evaluated the influence of opioids on many biological and immunological processes. The concentrations that have been used in these studies span a lar... Read More about Clinically relevant concentrations of opioids for in vitro studies.

Medical students writing on death, dying and palliative care : a qualitative analysis of reflective essays (2016)
Journal Article
Boland, J. W., Dikomitis, L., & Gadoud, A. (2016). Medical students writing on death, dying and palliative care : a qualitative analysis of reflective essays. BMJ supportive & palliative care, 6(4), 486-492. https://doi.org/10.1136/bmjspcare-2016-001110

Background: Medical students and doctors are becoming better prepared to care for patients with palliative care needs and support patients at the end of life. This preparation needs to start at medical school. Objective: To assess how medical student... Read More about Medical students writing on death, dying and palliative care : a qualitative analysis of reflective essays.

Communication and support from health-care professionals to families, with dependent children, following the diagnosis of parental life-limiting illness : a systematic review (2016)
Journal Article
Fearnley, R., & Boland, J. W. (2017). Communication and support from health-care professionals to families, with dependent children, following the diagnosis of parental life-limiting illness : a systematic review. Palliative medicine, 31(3), 212-222. https://doi.org/10.1177/0269216316655736

Background: Communication between parents and their children about parental life-limiting illness is stressful. Parents want support from health-care professionals; however, the extent of this support is not known. Awareness of family’s needs would h... Read More about Communication and support from health-care professionals to families, with dependent children, following the diagnosis of parental life-limiting illness : a systematic review.

The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease (2016)
Journal Article
Boland, J. W., Reigada, C., Yorke, J., Hart, S. P., Bajwah, S., Ross, J., …Johnson, M. J. (2016). The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease. Journal of palliative medicine, 19(5), 549-555. https://doi.org/10.1089/jpm.2015.0355

Background: Irrreversible interstitial lung disease (ILD) is associated with high morbidity and mortality. Palliative care needs of patients and caregivers are not routinely assessed; there is no tool to identify needs and triage support in clinical... Read More about The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease.

Is regular systemic opioid analgesia associated with shorter survival in adult patients with cancer? : a systematic literature review (2015)
Journal Article
Boland, J. W., Ziegler, L., Boland, E. G., McDermid, K., & Bennett, M. I. (2015). Is regular systemic opioid analgesia associated with shorter survival in adult patients with cancer? : a systematic literature review. Pain, 156(11), 2152-2163. https://doi.org/10.1097/j.pain.0000000000000306

© 2015 International Association for the Study of Pain. Opioids are important in the management of pain in patients with cancer. Clinicians and patients are sometimes concerned about the effect of opioids on survival, which might decrease opioid pres... Read More about Is regular systemic opioid analgesia associated with shorter survival in adult patients with cancer? : a systematic literature review.

A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research (2015)
Journal Article
Boland, J., Currow, D. C., Wilcock, A., Tieman, J., Hussain, J. A., Pitsillides, C., …Johnson, M. J. (2015). A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research. Journal of pain and symptom management, 49(4), 762-772. https://doi.org/10.1016/j.jpainsymman.2014.09.018

© 2015 American Academy of Hospice and Palliative Medicine. Context The challenges of palliative care clinical trial recruitment are well documented. Objectives The aim of the study was to review tested strategies to improve recruitment to trials of... Read More about A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research.

Effects of opioids on immunologic parameters that are relevant to anti-tumour immune potential in patients with cancer: A systematic literature review (2014)
Journal Article
Boland, J. W., McWilliams, K., Ahmedzai, S. H., & Pockley, A. G. (2014). Effects of opioids on immunologic parameters that are relevant to anti-tumour immune potential in patients with cancer: A systematic literature review. The British Journal of Cancer, 111(5), 866-873. https://doi.org/10.1038/bjc.2014.384

Background: The immune system has a central role in controlling cancer, and factors that influence protective antitumour immunity could therefore have a significant impact on the course of malignant disease. Opioids are essential for the management o... Read More about Effects of opioids on immunologic parameters that are relevant to anti-tumour immune potential in patients with cancer: A systematic literature review.

A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function (2013)
Journal Article
Boland, J. W., Foulds, G. A., Ahmedzai, S. H., & Graham Pockley, A. (2014). A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function. BMJ supportive & palliative care, 4(4), 357-367. https://doi.org/10.1136/bmjspcare-2013-000573

Background: Studies have demonstrated that whereas some opioids have little effect on immunity (eg, buprenorphine), others can be immunosuppressive (eg, morphine) or immunostimulatory (eg, tramadol). However, a variety of approaches have been used, e... Read More about A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function.

Palliative care for people with non-malignant lung disease: summary of current evidence and future direction (2013)
Journal Article
Boland, J., Martin, J., & Wells, A. U. (2013). Palliative care for people with non-malignant lung disease: summary of current evidence and future direction. Palliative medicine, 27(9), 811-816. https://doi.org/10.1177/0269216313493467

Background: The physical and psychosocial needs of patients with chronic non-malignant lung disease are comparable to those with lung cancer. This article will focus on chronic obstructive pulmonary disease, interstitial lung disease and cystic fibro... Read More about Palliative care for people with non-malignant lung disease: summary of current evidence and future direction.

End-of-life care for non-cancer patients (2013)
Journal Article
Boland, J., & Johnson, M. J. (2013). End-of-life care for non-cancer patients. BMJ supportive & palliative care, 3(1), 2-3. https://doi.org/10.1136/bmjspcare-2013-000446

[Extract]: The origins and early development of palliative care focussed on patients with cancer, apart from sporadic developments in a few non-malignant diseases such as MND and HIV. In the UK, this has been compounded by the setting of palliative c... Read More about End-of-life care for non-cancer patients.

Developing a service for patients with very severe chronic obstructive pulmonary disease (COPD) within resources (2013)
Journal Article
Boland, J., Owen, J., Ainscough, R., & Mahdi, H. (2014). Developing a service for patients with very severe chronic obstructive pulmonary disease (COPD) within resources. BMJ supportive & palliative care, 4(2), 196-201. https://doi.org/10.1136/bmjspcare-2012-000393

Chronic obstructive pulmonary disease (COPD) is a common life-limiting illness with significant burden for patient and carer. Despite this, access to supportive and specialist palliative care is inconsistent and implementation of published good pract... Read More about Developing a service for patients with very severe chronic obstructive pulmonary disease (COPD) within resources.