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All Outputs (53)

Towards an understanding of how appraisal of doctors produces its effects: a realist review (2017)
Journal Article
Brennan, N., Bryce, M., Pearson, M., Wong, G., Cooper, C., & Archer, J. (2017). Towards an understanding of how appraisal of doctors produces its effects: a realist review. Medical Education, 51(10), 1002-1013. https://doi.org/10.1111/medu.13348

© 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education Context: Revalidation was launched in the UK to provide assurances to the public that doctors are up to date and fit to practice. Appraisal is a fundamental compone... Read More about Towards an understanding of how appraisal of doctors produces its effects: a realist review.

Care of the dying : a qualitative exploration of foundation year doctors’ experiences (2017)
Journal Article
Redman, M., Pearce, J., Gajebasia, S., Johnson, M., & Finn, G. (2017). Care of the dying : a qualitative exploration of foundation year doctors’ experiences. Medical Education, 51(10), 1025-1036. https://doi.org/10.1111/medu.13358

Context Foundation Year doctors (FYs), who are newly qualified, are expected to provide care for dying patients. Experiences at this early mandatory stage of training may form the foundation for future encounters, but little is documented about wha... Read More about Care of the dying : a qualitative exploration of foundation year doctors’ experiences.

A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol (2017)
Journal Article
Currow, D., Watts, G. J., Johnson, M., McDonald, C. F., Miners, J. O., Somogyi, A. A., …Ekström, M. (2017). A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol. BMJ open, 7(7), 1-18. https://doi.org/10.1136/bmjopen-2017-018100

© Article author(s). Introduction Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended-release (ER) o... Read More about A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.

Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review (2017)
Journal Article
Papoutsi, C., Mattick, K., Pearson, M., Brennan, N., Briscoe, S., & Wong, G. (2017). Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review. The journal of antimicrobial chemotherapy, 72(9), 2418-2430. https://doi.org/10.1093/jac/dkx194

Background Antimicrobial resistance has led to widespread implementation of interventions for appropriate prescribing. However, such interventions are often adopted without an adequate understanding of the challenges facing doctors-in-training as key... Read More about Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review.

Influence of opioids on immune function in patients with cancer pain: from bench to bedside (2017)
Journal Article
Boland, J. W., & Pockley, A. G. (in press). Influence of opioids on immune function in patients with cancer pain: from bench to bedside. British Journal of Pharmacology, 175(14), 2726-2736. https://doi.org/10.1111/bph.13903

In patients with cancer, opioids are principally used for the management of acute surgical and chronic cancer-related pain. However, opioids have many non-analgesic effects, including direct and indirect effects on cancer cells and on anti-tumour imm... Read More about Influence of opioids on immune function in patients with cancer pain: from bench to bedside.

“Go make your face known”: Collaborative working through the lens of personal relationships (2017)
Journal Article
King, N., Bravington, A., Brooks, J., Melvin, J., & Wilde, D. (2017). “Go make your face known”: Collaborative working through the lens of personal relationships. International journal of integrated care, 17(4), Article 3. https://doi.org/10.5334/ijic.2574

© 2017 The Author(s). Background: Collaborative working between professionals is a key component of integrated care. The academic literature on it largely focuses either on integration between health and social care or on the dynamics of power and id... Read More about “Go make your face known”: Collaborative working through the lens of personal relationships.

Determinants of hospital death in haematological cancers: findings from a qualitative study (2017)
Journal Article
McCaughan, D., Roman, E., Smith, A. G., Garry, A., Johnson, M., Patmore, R., …Howell, D. A. (2018). Determinants of hospital death in haematological cancers: findings from a qualitative study. BMJ supportive & palliative care, 8(1), 78-86. https://doi.org/10.1136/bmjspcare-2016-001289

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. Objectives: Current UK health policy promotes enabling people to die in a place they choose, which for most is home. Despite this, patients with haema... Read More about Determinants of hospital death in haematological cancers: findings from a qualitative study.

Cognitive-emotional interventions for breathlessness in adults with advanced diseases (2017)
Journal Article
Bolzani, A., Rolser, S. M., Kalies, H., Maddocks, M., Rehfuess, E., Hutchinson, A., …Bausewein, C. (2017). Cognitive-emotional interventions for breathlessness in adults with advanced diseases. The Cochrane database of systematic reviews, 2017(6), Article CD012682. https://doi.org/10.1002/14651858.CD012682

© 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects and safety of interventions targeting cognition, emotion or both a... Read More about Cognitive-emotional interventions for breathlessness in adults with advanced diseases.

Respiratory interventions for breathlessness in adults with advanced diseases (2017)
Journal Article
Bolzani, A., Rolser, S. M., Kalies, H., Maddocks, M., Rehfuess, E., Swan, F., …Bausewein, C. (2017). Respiratory interventions for breathlessness in adults with advanced diseases. The Cochrane database of systematic reviews, 2017(6), Article CD012683. https://doi.org/10.1002/14651858.CD012683

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects and safety of interventions targeting respiration as the predominant underlying mechanism of effect to relieve breathlessness in adults suff... Read More about Respiratory interventions for breathlessness in adults with advanced diseases.

The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey (2017)
Journal Article
Chen, H., Currow, D. C., Dunn, L., Johnson, M. J., Macleod, U., & Allgar, V. (2018). The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey. Palliative medicine, 32(2), 357-365. https://doi.org/10.1177/0269216317711825

Background: Previous work shows that more affluent patients with cancer are more likely to die at home, whereas those dying from non-cancer conditions are more likely to die in hospital. Family caregivers are an important factor in determining place... Read More about The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey.

Time to improve informed consent for dialysis: an international perspective (2017)
Journal Article
Murtagh, F. E., Brennan, F., Stewart, C., Burgess, H., Davison, S. N., Moss, A. H., …Brown, M. (2017). Time to improve informed consent for dialysis: an international perspective. Clinical journal of the American Society of Nephrology, 12(6), 1001-1009. https://doi.org/10.2215/CJN.09740916

The literature reveals that current nephrology practice in obtaining informed consent for dialysis falls short of ethical and legal requirements. Meeting these requirements represents a significant challenge, especially because the benefits and risks... Read More about Time to improve informed consent for dialysis: an international perspective.

Improving Hospital at Home for frail older people: insights from a quality improvement project to achieve change across regional health and social care sectors (2017)
Journal Article
Pearson, M., Hemsley, A., Blackwell, R., Pegg, L., & Custerson, L. (2017). Improving Hospital at Home for frail older people: insights from a quality improvement project to achieve change across regional health and social care sectors. BMC health services research, 17(1), Article ARTN 387. https://doi.org/10.1186/s12913-017-2334-9

© 2017 The Author(s). Background: Against a background of rising numbers of frail older people, there is a need to improve quality and safety of services whilst containing costs. Improving patient outcomes requires change across hospital and communit... Read More about Improving Hospital at Home for frail older people: insights from a quality improvement project to achieve change across regional health and social care sectors.

Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis (2017)
Journal Article
Boland, J. W., Allgar, V., Boland, E. G., Oviasu, O., Agar, M., Currow, D. C., & Johnson, M. J. (2017). Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis. Journal of palliative medicine, 20(11), 1274-1279. https://doi.org/10.1089/jpm.2017.0129

Background: Medications for symptom management in palliative care have associated, but poorly understood, harms. Drug-related harms have important clinical implications, may impact on patients’ compliance and contribute to symptoms. Objective: To exp... Read More about Effect of opioids and benzodiazepines on clinical outcomes in patients receiving palliative care: an exploratory analysis.

Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations (2017)
Journal Article
Webster, L., Groskreutz, D., Grinbergs-Saull, A., Howard, R., O’Brien, J. T., Mountain, G., …Livingston, G. (2017). Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations. Health Technology Assessment, 21(26), 1-192. https://doi.org/10.3310/hta21260

© Queen’s Printer and Controller of HMSO 2017. Background: There is currently no disease-modifying treatment available to halt or delay the progression of the disease pathology in dementia. An agreed core set of the best-available and most appropriat... Read More about Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations.

Qualitative analysis of how patients decide that they want risk-reducing mastectomy, and the implications for surgeons in responding to emotionally-motivated patient requests (2017)
Journal Article
Brown, S. L., Whiting, D., Fielden, H. G., Saini, P., Beesley, H., Holcombe, C., …Salmon, P. (2017). Qualitative analysis of how patients decide that they want risk-reducing mastectomy, and the implications for surgeons in responding to emotionally-motivated patient requests. PLoS ONE, 12(5), e0178392. https://doi.org/10.1371/journal.pone.0178392

Objective: Contemporary approaches to medical decision-making advise that clinicians should respect patients' decisions. However, patients' decisions are often shaped by heuristics, such as being guided by emotion, rather than by objective risk and b... Read More about Qualitative analysis of how patients decide that they want risk-reducing mastectomy, and the implications for surgeons in responding to emotionally-motivated patient requests.

Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review (2017)
Journal Article
Hussain, J. A., Johnson, M. J., Currow, D. C., White, I. R., Currow, D., Hussain, J., …White, I. (2017). Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review. Journal of clinical epidemiology, 88, 81-91. https://doi.org/10.1016/j.jclinepi.2017.05.009

Objectives Assess (i) the quality of reporting and handling of missing data (MD) in palliative care trials, (ii) whether there are differences in the reporting of criteria specified by the Consolidated Standards of Reporting Trials (CONSORT) 2010 sta... Read More about Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review.

How many people will need palliative care in 2040? Past trends, future projections and implications for services (2017)
Journal Article
Etkind, S. N., Bone, A. E., Gomes, B., Lovell, N., Evans, C. J., Higginson, I. J., & Murtagh, F. E. M. (2017). How many people will need palliative care in 2040? Past trends, future projections and implications for services. BMC medicine, 15(1), https://doi.org/10.1186/s12916-017-0860-2

Background: Current estimates suggest that approximately 75% of people approaching the end-of-life may benefit from palliative care. The growing numbers of older people and increasing prevalence of chronic illness in many countries mean that more peo... Read More about How many people will need palliative care in 2040? Past trends, future projections and implications for services.

Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study (2017)
Journal Article
Kane, P. M., Murtagh, F. E., Ryan, K. R., Brice, M., Mahon, N. G., McAdam, B., …on behalf of BuildCARE. (2018). Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study. Palliative medicine, 32(2), 517-524. https://doi.org/10.1177/0269216317706426

Background: Recruitment challenges contribute to the paucity of palliative care research with advanced chronic heart failure patients. Aim: To describe the challenges and outline strategies of recruiting advanced chronic heart failure patients. Des... Read More about Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study.

Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness (2017)
Journal Article
Johnson, M. J., Yorke, J., Hansen-Flaschen, J., Lansing, R., Ekström, M., Similowski, T., & Currow, D. (2017). Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness. European respiratory journal, 49(5), Article 1602277. https://doi.org/10.1183/13993003.02277-2016

Copyright ©ERS 2017. Breathlessness that persists despite treatment for the underlying conditions is debilitating. Identifying this discrete entity as a clinical syndrome should raise awareness amongst patients, clinicians, service providers, researc... Read More about Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness.