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All Outputs (13)

Effects of dietary polyphenols on vascular endothelium and cardiovascular health (2017)
Thesis
Ehtesham, E. (2017). Effects of dietary polyphenols on vascular endothelium and cardiovascular health. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4219556

Introduction: Polyphenols have been suggested as being able to modulate the risk of cardiovascular disease. However, the molecular mechanisms underlying these effects are unclear and the literature lacks consistency and reproducibility, with in vitro... Read More about Effects of dietary polyphenols on vascular endothelium and cardiovascular health.

Phosphoproteomic analysis of platelet signalling cascades by flow cytometry (2014)
Thesis
Spurgeon, B. E. J. (2014). Phosphoproteomic analysis of platelet signalling cascades by flow cytometry. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4216373

The activation of blood platelets is a critical haemostatic response that serves to prevent haemorrhage, but unregulated platelet activation is associated with arterial thrombosis. Endothelial-derived inhibitors prostacyclin (PGI₂) and nitric oxide (... Read More about Phosphoproteomic analysis of platelet signalling cascades by flow cytometry.

GLP-1R, a novel receptor in platelets; and the use of liraglutide in the treatment of obesity in women with PCOS (2013)
Thesis
Kahal, H. (2013). GLP-1R, a novel receptor in platelets; and the use of liraglutide in the treatment of obesity in women with PCOS. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4215983

Studies investigating atherothrombotic risk in women with polycystic ovary syndrome (PCOS), in particular platelet function and carotid intima-media wall thickness (cIMT), have been confounded by not adequately accounting for obesity. Liraglutide is... Read More about GLP-1R, a novel receptor in platelets; and the use of liraglutide in the treatment of obesity in women with PCOS.

Effect of non-esterified fatty acids on insulin resistance and cardiovascular risk in polycystic ovary syndrome (2013)
Thesis
Aye, M. M. (2013). Effect of non-esterified fatty acids on insulin resistance and cardiovascular risk in polycystic ovary syndrome. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4215486

Introduction: Insulin resistance (IR) and obesity coexist in polycystic ovary syndrome (PCOS) and contribute to increased risk of diabetes and cardiovascular disease. An intrinsic insulin signalling defect is present in skeletal muscle of PCOS and it... Read More about Effect of non-esterified fatty acids on insulin resistance and cardiovascular risk in polycystic ovary syndrome.

Regulation of blood platelet function by nitric oxide (2013)
Thesis
Wake, J. D. (2013). Regulation of blood platelet function by nitric oxide. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4214507

Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix resulting in platelet activation and aggregation to form a haemostatic plug. This self-amplifying mechanism requires a tight control to prevent uncontrolled platelet... Read More about Regulation of blood platelet function by nitric oxide.

The effects of polyphenol rich chocolate on cardiovascular risk and glycaemic control in type 2 diabetes mellitus (2013)
Thesis
Mellor, D. D. (2013). The effects of polyphenol rich chocolate on cardiovascular risk and glycaemic control in type 2 diabetes mellitus. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4214543

Background:
Type 2 diabetes mellitus (T2DM) is characterised by increased rates of morbidity and mortality, much of which is related to cardiovascular disease. T2DM is considered to be a non-communicable disease, with its cause and aetiology linked... Read More about The effects of polyphenol rich chocolate on cardiovascular risk and glycaemic control in type 2 diabetes mellitus.

Interventions in patients at high cardiovascular risk (2011)
Thesis
González Seña, S. (2011). Interventions in patients at high cardiovascular risk. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4212418

Cardiovascular disease is a major cause of premature death in UK and an important contributor to escalating health costs. The risk of suffering a cardiovascular event is associated with multiple risk factors that can cluster in different pathological... Read More about Interventions in patients at high cardiovascular risk.

An evaluation of factors that affect glycaemic control and its measurements in diabetes mellitus (2010)
Thesis
Ng, J. M. (2010). An evaluation of factors that affect glycaemic control and its measurements in diabetes mellitus. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4210961

Diabetes mellitus (DM) is a complex and challenging disorder for the health care provider. Delayed detection and poor glycaemic control are both associated with a significant increase in the risk of patient morbidity and mortality. With almost 1 in 2... Read More about An evaluation of factors that affect glycaemic control and its measurements in diabetes mellitus.

Cardiovascular risk reduction in insulin resistant states (2009)
Thesis
Sathyapalan, T. (2009). Cardiovascular risk reduction in insulin resistant states. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4212907

Introduction: Insulin resistance is the hall mark of a number of pathological conditions and is thought to play a major role in the cardiovascular risk associated with them. This thesis critically evaluates two insulin resistant conditions - polycyst... Read More about Cardiovascular risk reduction in insulin resistant states.

The impact of thyroid dysfunction on cardiovascular risk (2008)
Thesis
Manuchehri, A. M. (2008). The impact of thyroid dysfunction on cardiovascular risk. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4208961

Thyroid dysfunction syndromes (hypo and hyperthyroidism) have major impacts on the cardiovascular system. Whilst the short term effects of thyroid dysfunction on the cardiovascular system are clinically obvious and well studied, the long term effects... Read More about The impact of thyroid dysfunction on cardiovascular risk.

Cardiometabolic aspects of polycystic ovary syndrome (2008)
Thesis
Cho, L. W. (2008). Cardiometabolic aspects of polycystic ovary syndrome. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4213102

Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting 6-7% of the population. It is characterised by chronic anovulation and hyperandrogenism with the clinical manifestation of oligomenorrhoea, hirsutism and acne. A ten to twenty... Read More about Cardiometabolic aspects of polycystic ovary syndrome.

Physical and chemical properties of sporopollenin exine particles (2008)
Thesis
Barrier, S. (2008). Physical and chemical properties of sporopollenin exine particles. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4213615

The chemical structure of sporopollenin was extensively reviewed, along with some considerations pertaining to its physical and biological properties. A comparative study is presented of extraction protocols to isolate exines from L. clavatum, in par... Read More about Physical and chemical properties of sporopollenin exine particles.