All Outputs (2)

Can Tissue-On-Chip Technology provide a platform for investigating differences in Extracellular Vesicle miRNA content between Thyroid Pathologies? (2025)
Thesis
Haigh, T. (2025). Can Tissue-On-Chip Technology provide a platform for investigating differences in Extracellular Vesicle miRNA content between Thyroid Pathologies?. (Thesis). Hull York Medical School, University of Hull and University of York. https://hull-repository.worktribe.com/output/5182708

This study uses an established method to maintain human thyroid tissue ex vivo on a tissue-on-chip device, allowing for the collection, isolation and interrogation of the small extracellular vesicles (sEVs) released directly from thyroid tissue. The... Read More about Can Tissue-On-Chip Technology provide a platform for investigating differences in Extracellular Vesicle miRNA content between Thyroid Pathologies?.

The Creation of 3D Thyroid Models to Investigate the Effects of Sorafenib on Thyroid Tumour Tissue (2025)
Thesis
Golebiewski, P. (2025). The Creation of 3D Thyroid Models to Investigate the Effects of Sorafenib on Thyroid Tumour Tissue. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/5087881

Thyroid cancer (TC) is the most common endocrine malignancy globally. While surgery and radioactive iodine (RAI) therapy generally yield favourable outcomes, prognosis worsens in RAI-refractory or resistant cases, highlighting the need for alternativ... Read More about The Creation of 3D Thyroid Models to Investigate the Effects of Sorafenib on Thyroid Tumour Tissue.