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All Outputs (410)

Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy (2025)
Journal Article
Mohamed, E., Goodman, S., Cooksey, L., Fletcher, D. M., Dean, O., Boncheva, V. B., Mills, K. I., Orchard, K. H., & Guinn, B.-A. (2025). Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy. Onco, 5(2), Article 19. https://doi.org/10.3390/onco5020019

Background: Adult B-cell acute lymphoblastic leukaemia (aB-ALL) is charac-terised by abnormal differentiation and proliferation of lymphoid progenitors. Despite a significant improvement in relapse-free and overall survival for children with BALL , a... Read More about Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy.

O-GlcNAcylation and Phosphorylation Crosstalk in Vascular Smooth Muscle Cells: Cellular and Therapeutic Significance in Cardiac and Vascular Pathologies (2025)
Journal Article
Bolanle, I. O., & Palmer, T. M. (2025). O-GlcNAcylation and Phosphorylation Crosstalk in Vascular Smooth Muscle Cells: Cellular and Therapeutic Significance in Cardiac and Vascular Pathologies. International Journal of Molecular Sciences, 26(7), Article 3303. https://doi.org/10.3390/ijms26073303

More than 400 different types of post-translational modifications (PTMs), including O-GlcNAcylation and phosphorylation, combine to co-ordinate almost all aspects of protein function. Often, these PTMs overlap and the specific relationship between O-... Read More about O-GlcNAcylation and Phosphorylation Crosstalk in Vascular Smooth Muscle Cells: Cellular and Therapeutic Significance in Cardiac and Vascular Pathologies.

Comprehensive Health Tracking Through Machine Learning and Wearable Technology (2025)
Journal Article
Yusuf, A., Jaber, T. A., & Gordon, N. (online). Comprehensive Health Tracking Through Machine Learning and Wearable Technology. Journal of Data Science and Intelligent Systems, https://doi.org/10.47852/bonviewjdsis52023588

The accurate interpretation of data from wearable devices is paramount in advancing personalized healthcare and disease prevention. This study explores the application of machine learning techniques to improve the interpretation of health metrics fro... Read More about Comprehensive Health Tracking Through Machine Learning and Wearable Technology.

Evaluating and implementing machine learning models for personalised mobile health app recommendations (2025)
Journal Article
Morenigbade, H., Al Jaber, T., Gordon, N., & Eke, G. (2025). Evaluating and implementing machine learning models for personalised mobile health app recommendations. PLoS ONE, 20(3 March), Article e0319828. https://doi.org/10.1371/journal.pone.0319828

This paper focuses on the evaluation and recommendation of healthcare applications in the mHealth field. The increase in the use of health applications, supported by an expanding mHealth market, highlights the importance of this research. In this stu... Read More about Evaluating and implementing machine learning models for personalised mobile health app recommendations.

Design of Cellular Hexagonal and Cancellous-like plates for laminectomy (2025)
Presentation / Conference Contribution
Ademuyiwa, S., Pearce, G., & Zioupos, P. (2024, September). Design of Cellular Hexagonal and Cancellous-like plates for laminectomy. Presented at SimBio-M 2024, Online

Our research investigates the development and evaluation of cancellous-like laminoplasty plate designs, focusing on honeycomb structures with thicknesses of 0.4mm, 0.8mm, 1.0mm, and 1.2mm, as well as a solid design. Laminoplasty plates are essential... Read More about Design of Cellular Hexagonal and Cancellous-like plates for laminectomy.

Perceived stigma mediates the relationship between health-related quality of life and depression in people with atopic dermatitis (2025)
Journal Article
North, C., van Beugen, S., & Holle, H. (2025). Perceived stigma mediates the relationship between health-related quality of life and depression in people with atopic dermatitis. Stigma and Health, https://doi.org/10.1037/sah0000622

Atopic dermatitis (AD) significantly impacts an individual’s life. Prior research has found positive correlations between the disease’s impact on daily quality of life, depression, and perceived stigmatization. However, the interaction of these varia... Read More about Perceived stigma mediates the relationship between health-related quality of life and depression in people with atopic dermatitis.

Proceedings: SimBio-M 2024 (ed. Peter Zioupos, Christophe Bastien) (2024)
Presentation / Conference Contribution
(2024, September). Proceedings: SimBio-M 2024 (ed. Peter Zioupos, Christophe Bastien). Presented at SimBio-M 2024, Online

This conference introduces new technologies, advances and tools in the various fields of Simulation in Biosciences and Multiphysics, notably in the areas of BioMechanics, BioMaterials, and BioMedicine.

While the conference concentrates mainly on t... Read More about Proceedings: SimBio-M 2024 (ed. Peter Zioupos, Christophe Bastien).

Fang experiences in Whitby’s goth/ic theatre (2024)
Journal Article
Wynne, C. (2024). Fang experiences in Whitby’s goth/ic theatre. Punk & Post-Punk, 13(2), 217-235. https://doi.org/10.1386/punk_00251_1

A sign which regularly appears on the door of St Mary’s Church in Whitby, North Yorkshire, alerts visitors that Dracula is not buried in the churchyard. Dracula arrives in Whitby in Bram Stoker’s fiction, exits the stage and finally turns to dust nea... Read More about Fang experiences in Whitby’s goth/ic theatre.

Are There Non-Invasive Biomarker(s) That Would Facilitate the Detection of Ovarian Torsion? A Systematic Review and Meta-Analysis (2024)
Journal Article
Naylor, M., Doherty, G., Draper, H., Fletcher, D. M., Rigby, A., Adedipe, T., & Guinn, B. A. (2024). Are There Non-Invasive Biomarker(s) That Would Facilitate the Detection of Ovarian Torsion? A Systematic Review and Meta-Analysis. International Journal of Molecular Sciences, 25(21), Article 11664. https://doi.org/10.3390/ijms252111664

Ovarian torsion (OT) is a rare gynaecological emergency that requires a prompt diagnosis for optimal patient management. To determine whether there were any biomarkers suitable for the non-invasive detection of OT, two independent reviewers performed... Read More about Are There Non-Invasive Biomarker(s) That Would Facilitate the Detection of Ovarian Torsion? A Systematic Review and Meta-Analysis.

Cancer screening attendance rates in transgender and gender-diverse patients: a systematic review and meta-analysis (2024)
Journal Article
Chan, A., Jamieson, C., Draper, H., O'Callaghan, S., & Guinn, B. A. (online). Cancer screening attendance rates in transgender and gender-diverse patients: a systematic review and meta-analysis. BMJ Evidence-Based Medicine, https://doi.org/10.1136/bmjebm-2023-112719

Objectives: To examine disparities in attendance rates at cancer screening services between transgender and gender-diverse (TGD) people in comparison with their cisgender (CG) counterparts, and to determine whether these differences were based on the... Read More about Cancer screening attendance rates in transgender and gender-diverse patients: a systematic review and meta-analysis.

Between Two Tides: A Practice Research Performance on the South Holderness Coast (2024)
Exhibition / Performance
Billing, C. (2024). Between Two Tides: A Practice Research Performance on the South Holderness Coast. [Live Performance]. 9 May 2024 - 10 May 2024

The performance 'Between Two Tides', staged by researchers from the University of Hull in May 2024, considered the intertwined histories of humans and nature along the South Holderness coast, a region grappling with the impacts of climate change. Thi... Read More about Between Two Tides: A Practice Research Performance on the South Holderness Coast.

Complement Dysregulation in Obese Versus Nonobese Polycystic Ovary Syndrome Patients (2023)
Journal Article
Butler, A. E., Moin, A. S. M., Sathyapalan, T., & Atkin, S. L. (2023). Complement Dysregulation in Obese Versus Nonobese Polycystic Ovary Syndrome Patients. Cells, 12(15), Article 2002. https://doi.org/10.3390/cells12152002

Introduction: Upregulation of complement system factors are reported to be increased in polycystic ovary syndrome (PCOS) and may be due to obesity and insulin resistance rather than inherently due to PCOS. We directly compared complement factors from... Read More about Complement Dysregulation in Obese Versus Nonobese Polycystic Ovary Syndrome Patients.

Efficacy and safety of pharmacotherapy for refractory or unexplained chronic cough: a systematic review and network meta-analysis (2023)
Journal Article
Zheng, Z., Huang, J., Xiang, Z., Wu, T., Lan, X., Xie, S., Lin, Z., Tang, K., Morice, A., Li, S., Song, W. J., & Chen, R. (2023). Efficacy and safety of pharmacotherapy for refractory or unexplained chronic cough: a systematic review and network meta-analysis. EClinicalMedicine, 62, Article 102100. https://doi.org/10.1016/j.eclinm.2023.102100

Background: Refractory chronic cough (RCC) has a significant impact on patient's health-related quality of life and represents a challenge in clinical management. However, the optimal treatment for RCC remains controversial. This study aimed to inves... Read More about Efficacy and safety of pharmacotherapy for refractory or unexplained chronic cough: a systematic review and network meta-analysis.

Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review (2023)
Journal Article
Paley, C. A., Boland, J. W., Santarelli, M., Murtagh, F. E., Ziegler, L., & Chapman, E. J. (2023). Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review. BMC Palliative Care, 22(1), Article 88. https://doi.org/10.1186/s12904-023-01202-8

BACKGROUND: Psychological distress is common in patients with cancer; interfering with physical and psychological wellbeing, and hindering management of physical symptoms. Our aim was to systematically review published evidence on non-pharmacological... Read More about Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review.

Advancements in the Treatment of CLL: The Rise of Zanubrutinib as a Preferred Therapeutic Option (2023)
Journal Article
Molica, S., Tam, C., Allsup, D., & Polliack, A. (2023). Advancements in the Treatment of CLL: The Rise of Zanubrutinib as a Preferred Therapeutic Option. Cancers, 15(14), Article 3737. https://doi.org/10.3390/cancers15143737

Ibrutinib, the first-in-class Bruton’s tyrosine kinase inhibitor (BTKi), is a commonly deployed therapeutic option for previously untreated and relapsed/refractory (R/R) patients with chronic lymphocytic leukemia (CLL). The use of ibrutinib is, howev... Read More about Advancements in the Treatment of CLL: The Rise of Zanubrutinib as a Preferred Therapeutic Option.

Antithrombotic drugs for cardiovascular risk reduction in patients with lower limb peripheral arterial disease: protocol for a systematic review and network meta-analysis of randomised controlled trials (2023)
Journal Article
Sidebottom, D. B., Huang, C., Carradice, D., Holt, P. J., John-Pierre, K., & Roy, I. N. (2023). Antithrombotic drugs for cardiovascular risk reduction in patients with lower limb peripheral arterial disease: protocol for a systematic review and network meta-analysis of randomised controlled trials. BMJ open, 13(8), Article e072355. https://doi.org/10.1136/bmjopen-2023-072355

INTRODUCTION: The optimal antithrombotic regimen to reduce the risk of vascular events in patients with peripheral arterial disease (PAD) is contentious. This systematic review and network meta-analysis (NMA) aims to define the relative efficacy and... Read More about Antithrombotic drugs for cardiovascular risk reduction in patients with lower limb peripheral arterial disease: protocol for a systematic review and network meta-analysis of randomised controlled trials.

Geriatric assessment prior to cancer treatment: a health economic evaluation   (2023)
Journal Article
Johnson, M. J., McKenzie, G. A. G., Lind, M. J., Kelly, C., & Parrott, S. (2023). Geriatric assessment prior to cancer treatment: a health economic evaluation  . Journal of Geriatric Oncology, 14(6), Article 101504. https://doi.org/10.1016/j.jgo.2023.101504

Introduction: To address uncertainty regarding the cost-effectiveness of implementing geriatric assessment (GA) in oncology practice, we undertook a synthetic, model-based economic evaluation. Materials and Methods: A decision-analytic model with emb... Read More about Geriatric assessment prior to cancer treatment: a health economic evaluation  .

A Distance Transformation Deep Forest Framework With Hybrid-Feature Fusion for CXR Image Classification (2023)
Journal Article
Hong, Q., Lin, L., Li, Z., Li, Q., Yao, J., Wu, Q., Liu, K., & Tian, J. (in press). A Distance Transformation Deep Forest Framework With Hybrid-Feature Fusion for CXR Image Classification. IEEE Transactions on Neural Networks and Learning Systems, https://doi.org/10.1109/TNNLS.2023.3280646

Detecting pneumonia, especially coronavirus disease 2019 (COVID-19), from chest X-ray (CXR) images is one of the most effective ways for disease diagnosis and patient triage. The application of deep neural networks (DNNs) for CXR image classification... Read More about A Distance Transformation Deep Forest Framework With Hybrid-Feature Fusion for CXR Image Classification.

Invisible in Plain Sight? Grandfathers Caring for Orphaned Grandchildren in Rural Malawi (2023)
Journal Article
Lazaro, M. C., Walker, L., & Robson, E. (in press). Invisible in Plain Sight? Grandfathers Caring for Orphaned Grandchildren in Rural Malawi. African Studies, https://doi.org/10.1080/00020184.2023.2212616

Millions of orphans, created by parental deaths due to the HIV/AIDS pandemic in sub-Saharan Africa, live with, and are cared for, by grandparents. Little research has considered how grandparents and, in particular, grandfathers, are caring for orphan... Read More about Invisible in Plain Sight? Grandfathers Caring for Orphaned Grandchildren in Rural Malawi.