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Old Tools, New Ways of Using Them: Harnessing Expert Opinions to Plan for Surprise in Marine Socio-Ecological Systems (2019)
Journal Article
Gladstone-Gallagher, R. V., Hope, J. A., Bulmer, R. H., Clark, D. E., Stephenson, F., Mangan, S., …Thrush, S. F. (2019). Old Tools, New Ways of Using Them: Harnessing Expert Opinions to Plan for Surprise in Marine Socio-Ecological Systems. Frontiers in Marine Science, 6, Article 696. https://doi.org/10.3389/fmars.2019.00696

Copyright © 2019 Gladstone-Gallagher, Hope, Bulmer, Clark, Stephenson, Mangan, Rullens, Siwicka, Thomas, Pilditch, Savage and Thrush. With globally accelerating rates of environmental disturbance, coastal marine ecosystems are increasingly prone to n... Read More about Old Tools, New Ways of Using Them: Harnessing Expert Opinions to Plan for Surprise in Marine Socio-Ecological Systems.

Online training improves medical students’ ability to recognise when a person is dying: The ORaClES randomised controlled trial (2019)
Journal Article
White, N., Oostendorp, L. J., Tomlinson, C., Yardley, S., Ricciardi, F., Gökalp, H., …Stone, P. (2020). Online training improves medical students’ ability to recognise when a person is dying: The ORaClES randomised controlled trial. Palliative medicine, 34(1), 134-144. https://doi.org/10.1177/0269216319880767

Background: Recognising dying is a key clinical skill for doctors, yet there is little training. Aim: To assess the effectiveness of an online training resource designed to enhance medical students’ ability to recognise dying. Design: Online... Read More about Online training improves medical students’ ability to recognise when a person is dying: The ORaClES randomised controlled trial.

Application of extracellular flux analysis for determining mitochondrial function in mammalian oocytes and early embryos (2019)
Journal Article
Muller, B., Lewis, N., Adeniyi, T., Leese, H. J., Brison, D. R., & Sturmey, R. G. (2019). Application of extracellular flux analysis for determining mitochondrial function in mammalian oocytes and early embryos. Scientific reports, 9(1), Article 16778. https://doi.org/10.1038/s41598-019-53066-9

Mitochondria provide the major source of ATP for mammalian oocyte maturation and early embryo development. Oxygen Consumption Rate (OCR) is an established measure of mitochondrial function. OCR by mammalian oocytes and embryos has generally been rest... Read More about Application of extracellular flux analysis for determining mitochondrial function in mammalian oocytes and early embryos.

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex (2019)
Journal Article
Qu, Y., Hahn, I., Lees, M., Parkin, J., Voelzmann, A., Dorey, K., …Prokop, A. (2019). Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex. eLife, 8, Article e50319. https://doi.org/10.7554/eLife.50319

Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon growth and regeneration through the ARF activator Efa6 in C. elegans, and by neurodevelopmenta... Read More about Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex.

Enhanced Clearing of Wound-Related Pathogenic Bacterial Biofilms Using Protease-Functionalized Antibiotic Nanocarriers (2019)
Journal Article
Weldrick, P. J., Hardman, M. J., & Paunov, V. N. (2019). Enhanced Clearing of Wound-Related Pathogenic Bacterial Biofilms Using Protease-Functionalized Antibiotic Nanocarriers. ACS Applied Materials & Interfaces, 11(47), 43902-43919. https://doi.org/10.1021/acsami.9b16119

© 2019 American Chemical Society. Biofilms are prevalent in chronic wounds and once formed are very hard to remove, which is associated with poor outcomes and high mortality rates. Biofilms are comprised of surface-attached bacteria embedded in an ex... Read More about Enhanced Clearing of Wound-Related Pathogenic Bacterial Biofilms Using Protease-Functionalized Antibiotic Nanocarriers.

Detecting falsehood relies on mismatch detection between sentence components (2019)
Journal Article
Weil, R., & Mudrik, L. (2020). Detecting falsehood relies on mismatch detection between sentence components. Cognition, 195, Article 104121. https://doi.org/10.1016/j.cognition.2019.104121

How do people process and evaluate falsehood of sentences? Do people need to compare presented information with the correct answer to determine that a sentence is false, or do they rely on a mismatch between presented sentence components? To illustra... Read More about Detecting falsehood relies on mismatch detection between sentence components.

Healthcare professionals must communicate with patients and relatives. They must enable informed, realistic and appropriate decisions in end-of-life pharmacotherapy (2019)
Journal Article
Lee, A. J. (2021). Healthcare professionals must communicate with patients and relatives. They must enable informed, realistic and appropriate decisions in end-of-life pharmacotherapy. Evidence-Based Nursing, ebnurs-2019-103179. https://doi.org/10.1136/ebnurs-2019-103179

Commentary on: Morin L, Wastesson JW, Laroche ML, et al. How many older adults receive drugs of questionable clinical benefit near the end of life? A cohort study. Palliat Med 2019;33:1080– 90. doi: 10.1177/0269216319854013.

Training people with dementia/cognitive impairment and their carers in the use of web-based supportive technologies (Innovative practice) (2019)
Journal Article
Cunnah, K., Howe, D., Thorpe, J., Dunn, R., Platt, R., White, C., …Wolverson, E. (2021). Training people with dementia/cognitive impairment and their carers in the use of web-based supportive technologies (Innovative practice). Dementia, 20(2), 796–806. https://doi.org/10.1177/1471301219887592

Little is known about the training and support people with dementia and their carers need to use digital solutions. This paper shares learning from a bespoke programme that successfully trained people with dementia or mild cognitive impairment and th... Read More about Training people with dementia/cognitive impairment and their carers in the use of web-based supportive technologies (Innovative practice).

Unmet nursing care needs on medical and surgical wards : a scoping review of patients’ perspectives (2019)
Journal Article
Bagnasco, A., Dasso, N., Rossi, S., Galanti, C., Varone, G., Catania, G., …Sasso, L. (2019). Unmet nursing care needs on medical and surgical wards : a scoping review of patients’ perspectives. Journal of clinical nursing, https://doi.org/10.1111/jocn.15089

© 2019 John Wiley & Sons Ltd Aims and objectives: To review and synthesise research studies on surgical and medical inpatients’ perceptions on unmet nursing care needs. Background: Missed nursing care is a growing phenomenon that has been shown to... Read More about Unmet nursing care needs on medical and surgical wards : a scoping review of patients’ perspectives.

Feasibility of a novel exercise prehabilitation programme in patients scheduled for elective colorectal surgery: a feasibility randomised controlled trial (2019)
Journal Article
Northgraves, M. J., Arunachalam, L., Madden, L. A., Marshall, P., Hartley, J. E., MacFie, J., & Vince, R. V. (2019). Feasibility of a novel exercise prehabilitation programme in patients scheduled for elective colorectal surgery: a feasibility randomised controlled trial. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, https://doi.org/10.1007/s00520-019-05098-0

© 2019, The Author(s). Background and objectives: To investigate the feasibility of delivering a functional exercise-based prehabilitation intervention and its effects on postoperative length of hospital stay, preoperative physical functioning and he... Read More about Feasibility of a novel exercise prehabilitation programme in patients scheduled for elective colorectal surgery: a feasibility randomised controlled trial.

The role of microphytobenthos in soft‐sediment ecological networks and their contribution to the delivery of multiple ecosystem services (2019)
Journal Article
Hope, J. A., Paterson, D. M., & Thrush, S. F. (2020). The role of microphytobenthos in soft‐sediment ecological networks and their contribution to the delivery of multiple ecosystem services. Journal of Ecology, 108(3), 815-830. https://doi.org/10.1111/1365-2745.13322

Sediment dwelling, microscopic primary producers, that occupy sediments in the photic zone, are commonly referred to as microphytobenthos (MPB). The MPB are essential components of soft-sediment systems, but are often overlooked when assessing coasta... Read More about The role of microphytobenthos in soft‐sediment ecological networks and their contribution to the delivery of multiple ecosystem services.

Building integrated thermoelectric air conditioners—a potentially fully environmentally friendly solution in building services (2019)
Journal Article
Ma, X., Zhao, H., Zhao, X., Li, G., & Shittu, S. (2019). Building integrated thermoelectric air conditioners—a potentially fully environmentally friendly solution in building services. Future Cities and Environment, 5(1), 12. https://doi.org/10.5334/fce.76

The refrigerants used in conventional vapor-compression air conditioning systems have detrimental effects on the global environment. Phasing-down hydrofluorocarbon (HFC) refrigerants for HVAC equipment over the next 20 years has been proposed. A ther... Read More about Building integrated thermoelectric air conditioners—a potentially fully environmentally friendly solution in building services.

Development of a Microfluidic Culture Paradigm for Ex Vivo Maintenance of Human Glioblastoma Tissue: A New Glioblastoma Model? (2019)
Journal Article
Olubajo, F., Achawal, S., & Greenman, J. (2020). Development of a Microfluidic Culture Paradigm for Ex Vivo Maintenance of Human Glioblastoma Tissue: A New Glioblastoma Model?. Translational Oncology, 13(1), 1-10. https://doi.org/10.1016/j.tranon.2019.09.002

© 2019 The Authors BACKGROUND: One way to overcome the genetic and molecular variations within glioblastoma is to treat each tumour on an individual basis. To facilitate this, we have developed a microfluidic culture paradigm that maintains human gli... Read More about Development of a Microfluidic Culture Paradigm for Ex Vivo Maintenance of Human Glioblastoma Tissue: A New Glioblastoma Model?.

Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis (2019)
Journal Article
Sin, D. D., O'Connor, G. T., Newell Jr., J. D., Allen, R. J., Guillen-Guio, B., Oldham, J. M., …Wain, L. V. (2020). Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine, 201(5), 564-574. https://doi.org/10.1164/rccm.201905-1017OC

Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by scarring of the lung that is believed to result from an atypical response to injury of the epithelium. Genome-wide association studies have reported signals of... Read More about Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis.

The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology (2019)
Journal Article
Hahn, I., Voelzmann, A., Liew, Y. T., Costa-Gomes, B., & Prokop, A. (2019). The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology. Neural Development, 14(1), Article 11. https://doi.org/10.1186/s13064-019-0134-0

Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging morphology, they usually need to be maintained for an organism's lifetime. This makes them key lesi... Read More about The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology.

Folate and Inflammation – links between folate and features of inflammatory conditions (2019)
Journal Article
Jones, P., Lucock, M., Scarlett, C. J., Veysey, M., & Beckett, E. L. (2019). Folate and Inflammation – links between folate and features of inflammatory conditions. Journal of Nutrition and Intermediary Metabolism, 18, Article 100104. https://doi.org/10.1016/j.jnim.2019.100104

Folate serves as a cofactor for one-carbon (1C) transfer reactions. These reactions are involved in the synthesis of DNA nucleotides, the amino acid methionine, and in the regulation of homocysteine (Hcy) levels. Emerging evidence suggests that these... Read More about Folate and Inflammation – links between folate and features of inflammatory conditions.

A low-cost aeroponic phenotyping system for storage root development: unravelling the below-ground secrets of cassava (Manihot esculenta) (2019)
Journal Article
Selvaraj, M. G., Montoya-P, M. E., Atanbori, J., French, A. P., & Pridmore, T. (2019). A low-cost aeroponic phenotyping system for storage root development: unravelling the below-ground secrets of cassava (Manihot esculenta). Plant Methods, 15(1), https://doi.org/10.1186/s13007-019-0517-6

© 2019 The Author(s). Background: Root and tuber crops are becoming more important for their high source of carbohydrates, next to cereals. Despite their commercial impact, there are significant knowledge gaps about the environmental and inherent reg... Read More about A low-cost aeroponic phenotyping system for storage root development: unravelling the below-ground secrets of cassava (Manihot esculenta).

Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. (2019)
Journal Article
Kochovska, S., Huang, C., Johnson, M. J., Agar, M. R., Fallon, M. T., Kaasa, S., …Currow, D. C. (2020). Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. Journal of pain and symptom management, 59(3), 637-645. https://doi.org/10.1016/j.jpainsymman.2019.10.026

© 2019 American Academy of Hospice and Palliative Medicine Context: Minimizing bias in randomized controlled trials (RCTs) includes intention-to-treat analyses. Hospice/palliative care RCTs are constrained by high attrition unpredictable when consent... Read More about Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention..