All Outputs (880)

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor (2020)
Journal Article
Maher, T. M., Simpson, J. K., Porter, J. C., Wilson, F. J., Chan, R., Eames, R., …Vahdati-Bolouri, M. (2020). A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor. Respiratory Research, 21(1), Article 75. https://doi.org/10.1186/s12931-020-01339-7

© 2020 The Author(s). Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease with poor prognosis and a significant unmet medical need. This study evaluated the safety, pharmacokinetics (PK) and target engagement in the... Read More about A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor.

A turn-off fluorescent probe for the detection of Cu2+ based on a tetraphenylethylene-functionalized salicylaldehyde Schiff-base (2020)
Journal Article
Xie, H. F., Yu, C. J., Huang, Y. L., Xu, H., Zhang, Q. L., Sun, X. H., …Redshaw, C. (2020). A turn-off fluorescent probe for the detection of Cu2+ based on a tetraphenylethylene-functionalized salicylaldehyde Schiff-base. Materials Chemistry Frontiers, 4(5), 1500-1506. https://doi.org/10.1039/c9qm00759h

A non-planar tetraphenylethylene-functionalized salicylaldehyde Schiff-base fluorescent probe (TPE-An-Py) with aggregation-induced enhanced emission (AIEE) characteristics was synthesized via a classical Knoevenagel condensation reaction, and exhibit... Read More about A turn-off fluorescent probe for the detection of Cu2+ based on a tetraphenylethylene-functionalized salicylaldehyde Schiff-base.

Constitution, Institutions and A Model for Economic Development in Nepal (2020)
Journal Article
Bhattarai, K. (2020). Constitution, Institutions and A Model for Economic Development in Nepal. Asian Journal of Economics and Finance, 2(2), 119-151

Nepal made significant progress in removing monarchy and terrors of Maoists in the last decade. It however lacks a stable solution for speedier economic growth and development as the major political parties are still struggling to institutionalize th... Read More about Constitution, Institutions and A Model for Economic Development in Nepal.

Understanding the presence of mental fatigue in English academy soccer players (2020)
Journal Article
Thompson, C. J., Noon, M., Towlson, C., Perry, J., Coutts, A. J., Harper, L. D., …Meyer, T. (2020). Understanding the presence of mental fatigue in English academy soccer players. Journal of sports sciences, 38(13), 1524-1530. https://doi.org/10.1080/02640414.2020.1746597

Research has demonstrated that induced mental fatigue impairs soccer-specific technical, tactical and physical performance in soccer players. The findings are limited by the lack of elite players and low ecological validity of the tasks used to induc... Read More about Understanding the presence of mental fatigue in English academy soccer players.

Positive spiritual climate supports transformational leadership as means to reduce nursing burnout and intent to leave (2020)
Journal Article
Wu, X., Hayter, M., Lee, A. J., Yuan, Y., Li, S., Bi, Y., …Zhang, Y. (2020). Positive spiritual climate supports transformational leadership as means to reduce nursing burnout and intent to leave. Journal of nursing management, 28(4), 804-813. https://doi.org/10.1111/jonm.12994

Aim To explore the relationship between spiritual climate and transformational leadership, and examine their impact on nurses perceived emotional exhaustion and intentions to quit. Background Transformational leadership is known to have a signif... Read More about Positive spiritual climate supports transformational leadership as means to reduce nursing burnout and intent to leave.

Augmented Leaching Pretreatments for Forest Wood Waste and Their Effect on Ash Composition and the Lignocellulosic Network (2020)
Journal Article
Taylor, M. J., Alabdrabalameer, H. A., Michopoulos, A. K., Volpe, R., & Skoulou, V. (2020). Augmented Leaching Pretreatments for Forest Wood Waste and Their Effect on Ash Composition and the Lignocellulosic Network. ACS Sustainable Chemistry and Engineering, 8(14), 5674-5682. https://doi.org/10.1021/acssuschemeng.0c00351

© 2020 American Chemical Society. By augmenting conventional leaching technologies for the removal of ash constituents from lignocellulosic waste residues, a cleaner and energy efficient solution can be provided for critical industrial problems such... Read More about Augmented Leaching Pretreatments for Forest Wood Waste and Their Effect on Ash Composition and the Lignocellulosic Network.

Influence of light and temperature cycles on the expression of circadian clock genes in the mussel Mytilus edulis (2020)
Journal Article
Chapman, E., Bonsor, B., Parsons, D. R., & Rotchell, J. (2020). Influence of light and temperature cycles on the expression of circadian clock genes in the mussel Mytilus edulis. Marine environmental research, 159, Article 104960. https://doi.org/10.1016/j.marenvres.2020.104960

Clock genes and environmental cues regulate essential biological rhythms. The blue mussel, Mytilus edulis, is an ecologically and economically important intertidal bivalve undergoing seasonal reproductive rhythms. We previously identified seasonal... Read More about Influence of light and temperature cycles on the expression of circadian clock genes in the mussel Mytilus edulis.

Chromium Nucleosynthesis and Silicon-Carbon Shell Mergers in Massive Stars (2020)
Journal Article
Côté, B., Jones, S., Herwig, F., & Pignatari, M. (2020). Chromium Nucleosynthesis and Silicon-Carbon Shell Mergers in Massive Stars. The Astrophysical journal, 892(1), Article 57. https://doi.org/10.3847/1538-4357/ab77ac

We analyze the production of the element Cr in galactic chemical evolution (GCE) models using the NuGrid nucleosynthesis yields set. We show that the unusually large [Cr/Fe] abundance at [Fe/H] ≈ 0 reported by previous studies using those yields and... Read More about Chromium Nucleosynthesis and Silicon-Carbon Shell Mergers in Massive Stars.

Bio-AKA: An efficient fingerprint based two factor user authentication and key agreement scheme (2020)
Journal Article
Bian, W., Gope, P., Cheng, Y., & Li, Q. (2020). Bio-AKA: An efficient fingerprint based two factor user authentication and key agreement scheme. Future generations computer systems : FGCS, 109, 45-55. https://doi.org/10.1016/j.future.2020.03.034

The fingerprint has long been used as one of the most important biological features in the field of biometrics. It is person-specific and remain identical though out one’s lifetime. Physically uncloneable functions (PUFs) have been used in authentica... Read More about Bio-AKA: An efficient fingerprint based two factor user authentication and key agreement scheme.

Gram-scale synthesis of alkoxide-derived nitrogen-doped carbon foam as a support for Fe-N-C electrocatalysts (2020)
Journal Article
Mufundirwa, A., Harrington, G. F., Ismail, M. S., Šmid, B., Cunning, B. V., Shundo, Y., …Lyth, S. M. (2020). Gram-scale synthesis of alkoxide-derived nitrogen-doped carbon foam as a support for Fe-N-C electrocatalysts. Nanotechnology, 31(22), Article 225401. https://doi.org/10.1088/1361-6528/ab76ed

Non-platinum group metal (non-PGM) catalysts for the oxygen reduction reaction (ORR) are set to reduce the cost of polymer electrolyte membrane fuel cells (PEFCs) by replacing platinum at the cathode. We previously developed unique nitrogen-doped car... Read More about Gram-scale synthesis of alkoxide-derived nitrogen-doped carbon foam as a support for Fe-N-C electrocatalysts.

Quantifying the sustainability of Bitcoin and Blockchain (2020)
Journal Article
Fry, J., & Serbera, J. (2020). Quantifying the sustainability of Bitcoin and Blockchain. Journal of Enterprise Information Management, 33(6), 1379-1394. https://doi.org/10.1108/JEIM-06-2018-0134

Purpose The authors develop new quantitative methods to estimate the level of speculation and long-term sustainability of Bitcoin and Blockchain. Design/methodology/approach The authors explore the practical application of speculative bubble mod... Read More about Quantifying the sustainability of Bitcoin and Blockchain.

Electrochemical immunoassay for the detection of stress biomarkers (2020)
Journal Article
Abdulsattar, J. O., Greenway, G. M., & Wadhawan, J. D. (2020). Electrochemical immunoassay for the detection of stress biomarkers. Heliyon, 6(3), Article e03558. https://doi.org/10.1016/j.heliyon.2020.e03558

A rapid electrochemical immunoassay method was developed to detect and measure stress biomarkers (cortisol and cortisone) in two biological samples (Zebrafish whole-body and artificial saliva). This methodology utilizes an immunoassay approach taking... Read More about Electrochemical immunoassay for the detection of stress biomarkers.

Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects (2020)
Journal Article
Kahal, H., Halama, A., Aburima, A., Bhagwat, A. M., Butler, A. E., Grauman, J., …Atkin, S. L. (2020). Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects. Scientific reports, 10(1), Article 4750. https://doi.org/10.1038/s41598-020-61531-z

Intensive diabetes control has been associated with increased mortality in type 2 diabetes (T2DM); this has been suggested to be due to increased hypoglycemia. We measured hypoglycemia-induced changes in endothelial parameters, oxidative stress marke... Read More about Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects.

Transient and non-uniform heat flux effect on solar thermoelectric generator with phase change material (2020)
Journal Article
Shittu, S., Li, G., Xuan, Q., Xiao, X., Zhao, X., Ma, X., & Akhlaghi, Y. G. (2020). Transient and non-uniform heat flux effect on solar thermoelectric generator with phase change material. Applied thermal engineering, 173, Article 115206. https://doi.org/10.1016/j.applthermaleng.2020.115206

Transient and non-uniform heat flux from solar concentrators can affect the performance of solar thermoelectric generators, which generate electricity from concentrated solar radiation. Therefore, this paper presents a detailed three-dimensional stud... Read More about Transient and non-uniform heat flux effect on solar thermoelectric generator with phase change material.

Topographic, hydraulic, and vegetative controls on bar and island development in mixed bedrock-alluvial, multi-channeled, dryland rivers (2020)
Journal Article
Milan, D. J., Tooth, S., & Heritage, G. (2020). Topographic, hydraulic, and vegetative controls on bar and island development in mixed bedrock-alluvial, multi-channeled, dryland rivers. Water Resources Research, 56(5), Article e2019WR026101. https://doi.org/10.1029/2019WR026101

We investigate processes of bedrock-core bar and island development in a bedrock-influenced anastomosed reach of the Sabie River, Kruger National Park (KNP), eastern South Africa. For sites subject to alluvial stripping during an extreme flood event... Read More about Topographic, hydraulic, and vegetative controls on bar and island development in mixed bedrock-alluvial, multi-channeled, dryland rivers.

A novel electromagnetic apparatus for in-situ synchrotron X-ray imaging study of the separation of phases in metal solidification (2020)
Journal Article
Koe, B., Abraham, C., Bailey, C., Greening, B., Small, M., Connolley, T., & Mi, J. (2020). A novel electromagnetic apparatus for in-situ synchrotron X-ray imaging study of the separation of phases in metal solidification. HardwareX, 7, Article e00104. https://doi.org/10.1016/j.ohx.2020.e00104

As a part of a research into new techniques for purifying recycled aluminium alloys, a novel electromagnetic apparatus had been developed for investigating in real-time the separation mechanisms of detrimental inclusions in aluminium alloy melts unde... Read More about A novel electromagnetic apparatus for in-situ synchrotron X-ray imaging study of the separation of phases in metal solidification.

Stress appraisals influence athletic performance and psychophysiological response during 16.1 km cycling time trials (2020)
Journal Article
Thompson, M. A., Toner, J., Perry, J. L., Burke, R., & Nicholls, A. R. (2020). Stress appraisals influence athletic performance and psychophysiological response during 16.1 km cycling time trials. Psychology of sport and exercise, 49(July), Article 101682. https://doi.org/10.1016/j.psychsport.2020.101682

Objectives: We examined how stress appraisals were associated with emotions, coping behaviours, as well as subjective and objective measures of performance. Design: Prospective field- and laboratory-based studies. Methods: In Study 1, 192 athletes... Read More about Stress appraisals influence athletic performance and psychophysiological response during 16.1 km cycling time trials.

Bridging the Fields of Careers and Project Management (2020)
Journal Article
Akkermans, J., Chipulu, M., Ojiako, U., & Williams, T. (2020). Bridging the Fields of Careers and Project Management. Project management journal, 51(2), 123-134. https://doi.org/10.1177/8756972820910605

Supporting social prescribing in primary care by linking people to local assets: A realist review (2020)
Journal Article
Tierney, S., Wong, G., Roberts, N., Boylan, A. M., Park, S., Abrams, R., …Mahtani, K. R. (2020). Supporting social prescribing in primary care by linking people to local assets: A realist review. BMC medicine, 18(1), Article 49. https://doi.org/10.1186/s12916-020-1510-7

© 2020 The Author(s). Background: Social prescribing is a way of addressing the 'non-medical' needs (e.g. loneliness, debt, housing problems) that can affect people's health and well-being. Connector schemes (e.g. delivered by care navigators or link... Read More about Supporting social prescribing in primary care by linking people to local assets: A realist review.

Distribution of variants in multiple vitamin D-related loci (DHCR7/NADSYN1, GC, CYP2R1, CYP11A1, CYP24A1, VDR, RXRα and RXRγ) vary between European, East-Asian and Sub-Saharan African-ancestry populations (2020)
Journal Article
Jones, P., Lucock, M., Chaplin, G., Jablonski, N. G., Veysey, M., Scarlett, C., & Beckett, E. (2020). Distribution of variants in multiple vitamin D-related loci (DHCR7/NADSYN1, GC, CYP2R1, CYP11A1, CYP24A1, VDR, RXRα and RXRγ) vary between European, East-Asian and Sub-Saharan African-ancestry populations. Genes and Nutrition, 15(1), Article 5. https://doi.org/10.1186/s12263-020-00663-3

Background The frequency of vitamin D-associated gene variants appear to reflect changes in long-term ultraviolet B radiation (UVB) environment, indicating interactions exist between the primary determinant of vitamin D status, UVB exposure and gene... Read More about Distribution of variants in multiple vitamin D-related loci (DHCR7/NADSYN1, GC, CYP2R1, CYP11A1, CYP24A1, VDR, RXRα and RXRγ) vary between European, East-Asian and Sub-Saharan African-ancestry populations.