All Outputs (694)

Dipole-dipole correlations in the nematic phases of symmetric cyanobiphenyl dimers and their binary mixtures with 5CB (2023)
Journal Article
Zavvou, E. E., Ramou, E., Ahmed, Z., Welch, C., Mehl, G. H., Vanakaras, A. G., & Karahaliou, P. K. (2023). Dipole-dipole correlations in the nematic phases of symmetric cyanobiphenyl dimers and their binary mixtures with 5CB. Soft matter, 19(47), 9224-9238. https://doi.org/10.1039/d3sm01017a

We report on the temperature dependence of birefringence and of the static dielectric permittivity tensor in a series of binary mixtures between the symmetric, bent-shaped, 1′′,9′′-bis(4-cyanobiphenyl-4′-yl)nonane (CB9CB) dimer and the monomeric nema... Read More about Dipole-dipole correlations in the nematic phases of symmetric cyanobiphenyl dimers and their binary mixtures with 5CB.

A literature review of fault diagnosis based on ensemble learning (2023)
Journal Article
Mian, Z., Deng, X., Dong, X., Tian, Y., Cao, T., Chen, K., & Jaber, T. A. (2024). A literature review of fault diagnosis based on ensemble learning. Engineering applications of artificial intelligence, 127, Article 107357. https://doi.org/10.1016/j.engappai.2023.107357

The accuracy of fault diagnosis is an important indicator to ensure the reliability of key equipment systems. Ensemble learning integrates different weak learning methods to obtain stronger learning and has achieved remarkable results in the field of... Read More about A literature review of fault diagnosis based on ensemble learning.

How can NHS trusts in England optimise strategies to improve the mental health and well-being of hospital doctors? The Care Under Pressure 3 (CUP3) realist evaluation study protocol (2023)
Journal Article
Bramwell, C., Carrieri, D., Melvin, A., Pearson, A., Scott, J., Hancock, J., …Mattick, K. (2023). How can NHS trusts in England optimise strategies to improve the mental health and well-being of hospital doctors? The Care Under Pressure 3 (CUP3) realist evaluation study protocol. BMJ open, 13(11), Article e073615. https://doi.org/10.1136/bmjopen-2023-073615

INTRODUCTION: The growing incidence of mental ill health in doctors was a major issue in the UK and internationally, even prior to the COVID-19 pandemic. It has significant and far-reaching implications, including poor quality or inconsistent patient... Read More about How can NHS trusts in England optimise strategies to improve the mental health and well-being of hospital doctors? The Care Under Pressure 3 (CUP3) realist evaluation study protocol.

Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets (2023)
Journal Article
Gil, H. M., Booth, Z., Price, T. W., Lee, J., Naylor‐Adamson, L., Avery, M., …Stasiuk, G. J. (in press). Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets. Small, Article 2304881. https://doi.org/10.1002/smll.202304881

InP/ZnS quantum dots (QDs) have received a large focus in recent years as a safer alternative to heavy metal-based QDs. Given their intrinsic fluorescent imaging capabilities, these QDs can be potentially relevant for in vivo platelet imaging. The In... Read More about Impact of Surface Ligand on the Biocompatibility of InP/ZnS Quantum Dots with Platelets.

Euler-Euler LES of bubble column bubbly flows by considering sub-grid scale turbulent dispersion effect on modulating bubble transport (2023)
Journal Article
Long, S., Yang, X., Yang, J., Li, B., Shi, W., & Sommerfeld, M. (2023). Euler-Euler LES of bubble column bubbly flows by considering sub-grid scale turbulent dispersion effect on modulating bubble transport. Chemical Engineering Journal, 477, Article 147239. https://doi.org/10.1016/j.cej.2023.147239

It has now been recognised and generally accepted that turbulent dispersion may be modelled using the time average of the fluctuating part of the interphase momentum, employing the drag the Favre averaged drag model for turbulent dispersion in Euleri... Read More about Euler-Euler LES of bubble column bubbly flows by considering sub-grid scale turbulent dispersion effect on modulating bubble transport.

Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial (2023)
Journal Article
Santos-Ferreira, D., Diaz, S. O., Ferreira, J. P., Girerd, N., Pellicori, P., Mariottoni, B., …Zannad, F. (2024). Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial. ESC Heart Failure, 11(1), 209-218. https://doi.org/10.1002/ehf2.14465

Aims: We aim to characterize the clinical and proteomic profiles of patients at risk of developing heart failure (HF), with and without coronary artery disease (CAD) or prior myocardial infarction (MI). Methods and results: HOMAGE evaluated the effec... Read More about Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial.

Targeting TP53 disruption in chronic lymphocytic leukemia: Current strategies and future directions (2023)
Journal Article
Molica, S., Tam, C., Allsup, D., & Polliack, A. (in press). Targeting TP53 disruption in chronic lymphocytic leukemia: Current strategies and future directions. Hematological Oncology, https://doi.org/10.1002/hon.3238

In the modern era of Chronic Lymphocytic Leukemia (CLL) targeted therapy, the loss of p53 function due to genetic abnormalities remains a significant challenge. This is because even targeted agents, which are currently the mainstay of treatment for C... Read More about Targeting TP53 disruption in chronic lymphocytic leukemia: Current strategies and future directions.

The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance (2023)
Journal Article
Mahmoudi-Aznaveh, A., Tavoosidana, G., Najmabadi, H., Azizi, Z., & Ardestani, A. (2023). The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance. Frontiers in endocrinology, 14, Article 1303930. https://doi.org/10.3389/fendo.2023.1303930

Introduction: An insufficient functional beta cell mass is a core pathological hallmark of type 2 diabetes (T2D). Despite the availability of several effective pharmaceuticals for diabetes management, there is an urgent need for novel medications to... Read More about The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance.

Women’s football subculture of misogyny: the escalation to online gender-based violence (2023)
Journal Article
Fenton, A., Ahmed, W., Hardey, M., Boardman, R., & Kavanagh, E. (in press). Women’s football subculture of misogyny: the escalation to online gender-based violence. European Sport Management Quarterly, https://doi.org/10.1080/16184742.2023.2270566

Research question Given the worldwide growth of women’s football and its presence on social media, it is essential to explore and understand fan attitudes and culture. Research methods This article provides the first empirical social media netnogr... Read More about Women’s football subculture of misogyny: the escalation to online gender-based violence.

Reserving the objectionable: reprisals against enemy civilians, the United Kingdom and 1977 Additional Protocol I (2023)
Journal Article
Moir, L. (in press). Reserving the objectionable: reprisals against enemy civilians, the United Kingdom and 1977 Additional Protocol I. The Military Law and the Law of War Review, 61(2),

Belligerent reprisals are a largely discredited method for the enforcement of international humanitarian law, which have been progressively limited and prohibited. Additional Protocol I of 1977 prohibits reprisals against enemy civilians but the Unit... Read More about Reserving the objectionable: reprisals against enemy civilians, the United Kingdom and 1977 Additional Protocol I.

Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice (2023)
Journal Article
Aryankhesal, A., Blake, J., Wong, G., Megson, M., Briscoe, S., Allan, L., …Fox, C. (in press). Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice. The British journal of general practice : the journal of the Royal College of General Practitioners, https://doi.org/10.3399/BJGP.2023.0171

Background Sleep disturbance (SD) is a prevalent condition among people living with dementia (PLwD) or mild cognitive impairment (MCI). Its assessment and management within primary care is complex due to the comorbidities, older age and cognitive im... Read More about Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice.

The black widow pulsar J1641+8049 in the optical, radio, and X-rays (2023)
Journal Article
Kirichenko, A. Y., Zharikov, S. V., Karpova, A. V., Fonseca, E., Zyuzin, D. A., Shibanov, Y. A., …Swiggum, J. K. (2024). The black widow pulsar J1641+8049 in the optical, radio, and X-rays. Monthly notices of the Royal Astronomical Society, 527(3), 4563-4572. https://doi.org/10.1093/mnras/stad3391

PSR J1641+8049 is a 2 ms black widow pulsar with the 2.2 h orbital period detected in the radio and γ -rays. We performed new phase-resolved multiband photometry of PSR J1641+8049 using the OSIRIS instrument at the Gran Telescopio Canarias. The obtai... Read More about The black widow pulsar J1641+8049 in the optical, radio, and X-rays.

Improved traceability in seafood supply chains is achievable by minimising vulnerable nodes in processing and distribution networks (2023)
Journal Article
Hopkins, C. R., Roberts, S. I., Caveen, A. J., Graham, C., & Burns, N. M. (2024). Improved traceability in seafood supply chains is achievable by minimising vulnerable nodes in processing and distribution networks. Marine Policy, 159, Article 105910. https://doi.org/10.1016/j.marpol.2023.105910

Seafood is a globally traded commodity, often involving complex supply chains which have varying degrees of traceability. A robust traceability system for seafood supply chains enables the collection and communication of key information about catch a... Read More about Improved traceability in seafood supply chains is achievable by minimising vulnerable nodes in processing and distribution networks.

Molecular Analysis at Relapse of Patients Treated on the Ibrutinib and Rituximab Arm of the National Multi-Centre Phase III FLAIR Study in Previously Untreated CLL Patients (2023)
Journal Article
Sarma, A., Evans, C., Dalal, S., Webster, N., Rawstron, A., Shingles, J., …Hillmen, P. (2023). Molecular Analysis at Relapse of Patients Treated on the Ibrutinib and Rituximab Arm of the National Multi-Centre Phase III FLAIR Study in Previously Untreated CLL Patients. Blood, 142(Supplement 1), 4636-4636. https://doi.org/10.1182/blood-2023-188597

Using Peripheral Blood (PB) Measurable Residual Disease (MRD) Levels to Predict <0.01% Bone Marrow Disease (BM uMRD4): Identification of Effective PB Targets for CLL Treatment Cessation in the Ibrutinib+Venetoclax Arm of the FLAIR Trial (2023)
Journal Article
Rawstron, A., Webster, N., Dalal, S., de Tute, R. M., Bell, S., Cairns, D. A., …Hillmen, P. (2023). Using Peripheral Blood (PB) Measurable Residual Disease (MRD) Levels to Predict <0.01% Bone Marrow Disease (BM uMRD4): Identification of Effective PB Targets for CLL Treatment Cessation in the Ibrutinib+Venetoclax Arm of the FLAIR Trial. Blood, 142(Supplement 1), 632-632. https://doi.org/10.1182/blood-2023-187943

Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study (2023)
Journal Article
Hillmen, P., Cairns, D. A., Bloor, A. J. C., Allsup, D., Cwynarski, K., Pettitt, A., …Munir, T. (2023). Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study. Blood, 142(Supplement 1), 631. https://doi.org/10.1182/blood-2023-178298

Introduction: Ibrutinib (I), an irreversible Btk inhibitor, and venetoclax (V), a Bcl-2 inhibitor, improve CLL outcomes in trials compared to chemoimmunotherapy. I and V target two key pathophysiological pathways in CLL and should be synergistic. Thi... Read More about Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study.

Characterisation of Novel and High Performing Double-Sided Microporous-Layers-Coated Gas Diffusion Layers for Polymer Electrolyte Membrane Fuel Cells (2023)
Journal Article
Ruscillo, F., Zhang, K., Ismail, M. S., Hughes, K. J., Ingham, D. B., Ma, L., & Pourkashanian, M. (2023). Characterisation of Novel and High Performing Double-Sided Microporous-Layers-Coated Gas Diffusion Layers for Polymer Electrolyte Membrane Fuel Cells. Energies, 16(22), Article 7601. https://doi.org/10.3390/en16227601

This study aims to experimentally evaluate the impact of a double-sided microporous layer coating on gas diffusion layers in terms of their key properties and fuel cell performance, in comparison to conventional single-sided coated gas diffusion laye... Read More about Characterisation of Novel and High Performing Double-Sided Microporous-Layers-Coated Gas Diffusion Layers for Polymer Electrolyte Membrane Fuel Cells.

BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping (2023)
Journal Article
Clark, J., Salins, N., Pearson, M., Spathis, A., Currow, D. C., Williams, S., & Johnson, M. (2023). BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping. PLoS ONE, 18(11 November), Article e0293918. https://doi.org/10.1371/journal.pone.0293918

Background Breathlessness that persists despite treatment of causal disease(s) is disabling, associated with high therapy-related costs and poor socioeconomic outcomes. Low resource countries bear a disproportionate burden of respiratory problems, of... Read More about BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping.

Conversations on grief and hope: a collaborative autoethnographic account exploring the lifeworlds of international youth engaged with climate action (2023)
Journal Article
Jones, L., Parsons, K. J., Halstead, F., Ngoc Nguyen, D. N., Pham, H. T., Pham, D. L., …Parsons, D. R. (2023). Conversations on grief and hope: a collaborative autoethnographic account exploring the lifeworlds of international youth engaged with climate action. Journal of the British Academy, 11(S3), 69-117. https://doi.org/10.5871/JBA/011S3.069

This paper explores the lifeworlds of international youth involved in climate and/or environmental social action, narratives that have been largely absent from a literature that has tended to focus on ‘traditional’ youth activists located in the urba... Read More about Conversations on grief and hope: a collaborative autoethnographic account exploring the lifeworlds of international youth engaged with climate action.

A Chandra Study of the NGC 7618/UGC 12491 Major Group Merger at Apogee: Multiple Cold Fronts, Boxy Wings, Filaments, and Arc-shaped Slingshot Tails (2023)
Journal Article
Machacek, M. E., Jones, C., Kraft, R. P., Forman, W. R., Roediger, E., Sheardown, A., & Wan, J. T. (2023). A Chandra Study of the NGC 7618/UGC 12491 Major Group Merger at Apogee: Multiple Cold Fronts, Boxy Wings, Filaments, and Arc-shaped Slingshot Tails. The Astrophysical journal, 958(1), Article 93. https://doi.org/10.3847/1538-4357/ad00b2

Analyses of major group mergers are key to understanding the evolution of large-scale structure in the Universe and the microphysical properties of the hot gas in these systems. We present imaging and spectral analyses of deep Chandra observations of... Read More about A Chandra Study of the NGC 7618/UGC 12491 Major Group Merger at Apogee: Multiple Cold Fronts, Boxy Wings, Filaments, and Arc-shaped Slingshot Tails.