All Outputs (13702)

Heat induces multiomic and phenotypic stress propagation in zebrafish embryos (2023)
Journal Article
Feugere, L., Bates, A., Emagbetere, T., Chapman, E., Malcolm, L., Bulmer, K., …Wollenberg Valero, K. C. (2023). Heat induces multiomic and phenotypic stress propagation in zebrafish embryos. PNAS Nexus, 2(5), Article pgad137. https://doi.org/10.1093/pnasnexus/pgad137

Heat alters biology from molecular to ecological levels, but may also have unknown indirect effects. This includes the concept that animals exposed to abiotic stress can induce stress in naive receivers. Here, we provide a comprehensive picture of th... Read More about Heat induces multiomic and phenotypic stress propagation in zebrafish embryos.

Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial) (2023)
Journal Article
Sousa, M. S., Martin, P., Johnson, M. J., Lind, M., Maddocks, M., Bullock, A., Agar, M., Chang, S., Kochovska, S., Kinchin, I., Morgan, D., Fazekas, B., Razmovski-Naumovski, V., Lee, J. T., Itchins, M., Bray, V., & Currow, D. C. (2023). Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial). PLoS ONE, 18(5 May), Article e0285850. https://doi.org/10.1371/journal.pone.0285850

Anorexia is experienced by most people with lung cancer during the course of their disease and treatment. Anorexia reduces response to chemotherapy and the ability of patients to cope with, and complete their treatment leading to greater morbidity, p... Read More about Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial).

Ibrutinib and rituximab versus fludarabine, cyclophosphamide, and rituximab for patients with previously untreated chronic lymphocytic leukaemia (FLAIR): interim analysis of a multicentre, open-label, randomised, phase 3 trial (2023)
Journal Article
Hillmen, P., Pitchford, A., Bloor, A., Broom, A., Young, M., Kennedy, B., Walewska, R., Furtado, M., Preston, G., Neilson, J. R., Pemberton, N., Sidra, G., Morley, N., Cwynarski, K., Schuh, A., Forconi, F., Elmusharaf, N., Paneesha, S., Fox, C. P., Howard, D. R., …Munir, T. (2023). Ibrutinib and rituximab versus fludarabine, cyclophosphamide, and rituximab for patients with previously untreated chronic lymphocytic leukaemia (FLAIR): interim analysis of a multicentre, open-label, randomised, phase 3 trial. The lancet oncology, 24(5), 535-552. https://doi.org/10.1016/S1470-2045%2823%2900144-4

Background: The approval of Bruton tyrosine kinase (BTK) inhibitors in patients with previously untreated chronic lymphocytic leukaemia (CLL) was based on trials which compared ibrutinib with alkylating agents in patients considered unfit for fludara... Read More about Ibrutinib and rituximab versus fludarabine, cyclophosphamide, and rituximab for patients with previously untreated chronic lymphocytic leukaemia (FLAIR): interim analysis of a multicentre, open-label, randomised, phase 3 trial.

The Design and Use of Questionnaires in Educational Research: A New (Student) Researcher Guide (2023)
Journal Article
Holmes, A. G. D. (2023). The Design and Use of Questionnaires in Educational Research: A New (Student) Researcher Guide. Innovare Journal of Education, 11(3), 1-5. https://doi.org/10.22159/ijoe.2023v11i3.47599

Questionnaires are widely used in educational research to gather data about the top under investigation. This is because they are cost-effective, relatively simple to use and can provide researchers with a large amount of data... Read More about The Design and Use of Questionnaires in Educational Research: A New (Student) Researcher Guide.

Advancements and challenges in gender equity in British policing (2023)
Journal Article
Laverick, W., Joyce, P., & Cunningham, E. (2023). Advancements and challenges in gender equity in British policing. Policing Insight,

A series of recent reviews and reports have highlighted issues around misogyny and gender inequality in UK policing; in this article, Laverick, Joyce and Cunningham explore the context of some of those issues, and consider the advances as well as the... Read More about Advancements and challenges in gender equity in British policing.

High density lipoprotein-associated proteins in non-obese women with and without polycystic ovary syndrome (2023)
Journal Article
Butler, A. E., Moin, A. S. M., Reiner, Ž., Sathyapalan, T., Jamialahmadi, T., Sahebkar, A., & Atkin, S. L. (2023). High density lipoprotein-associated proteins in non-obese women with and without polycystic ovary syndrome. Frontiers in endocrinology, 14, Article 1117761. https://doi.org/10.3389/fendo.2023.1117761

Introduction: Dyslipidemia frequently occurs in women with polycystic ovary syndrome (PCOS), but it is unclear whether dyslipidemia is due to obesity and insulin resistance (IR) or is inherent to PCOS. To address this, proteomic analysis of proteins... Read More about High density lipoprotein-associated proteins in non-obese women with and without polycystic ovary syndrome.

Editorial: Innovations in dementia and ageing care (2023)
Journal Article
Quinn, C., Wolverson, E., & Mountain, G. (2023). Editorial: Innovations in dementia and ageing care. Frontiers in Rehabilitation Sciences, 4, Article 1191633. https://doi.org/10.3389/fresc.2023.1191633

KEYWORDS Alzheimer's disease, carer, psychosocial interventions, health serivces, community, quality of life, frailty Editorial on the Research Topic Innovations in dementia and ageing care The COVID-19 pandemic has highlighted how quality of life ca... Read More about Editorial: Innovations in dementia and ageing care.

Multi-agent reinforcement learning control of a hydrostatic wind turbine-based farm (2023)
Journal Article
Huang, Y., Lin, S., & Zhao, X. (2023). Multi-agent reinforcement learning control of a hydrostatic wind turbine-based farm. IEEE Transactions on Sustainable Energy, https://doi.org/10.1109/tste.2023.3270761

This paper leverages multi-agent reinforcement learning (MARL) to develop an efficient control system for a wind farm comprising a new type of wind turbines with hydrostatic transmission. The primary motivation for hydrostatic wind turbines (HWT) is... Read More about Multi-agent reinforcement learning control of a hydrostatic wind turbine-based farm.

Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019 (2023)
Journal Article
Momtazmanesh, S., Moghaddam, S. S., Ghamari, S. H., Rad, E. M., Rezaei, N., Shobeiri, P., …Soyiri, I. (2023). Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019. EClinicalMedicine, 59, Article 101936. https://doi.org/10.1016/j.eclinm.2023.101936

Background: Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-co... Read More about Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019.

Versatile Microfluidics for Biofabrication Platforms Enabled by an Agile and Inexpensive Fabrication Pipeline (2023)
Journal Article
Moetazedian, A., Candeo, A., Liu, S., Hughes, A., Nasrollahi, V., Saadat, M., …Poologasundarampillai, G. (2023). Versatile Microfluidics for Biofabrication Platforms Enabled by an Agile and Inexpensive Fabrication Pipeline. Advanced Healthcare Materials, 12(26), Article 2300636. https://doi.org/10.1002/adhm.202300636

Microfluidics have transformed diagnosis and screening in regenerative medicine. Recently, they are showing much promise in biofabrication. However, their adoption is inhibited by costly and drawn-out lithographic processes thus limiting progress. He... Read More about Versatile Microfluidics for Biofabrication Platforms Enabled by an Agile and Inexpensive Fabrication Pipeline.

Deaths at home, area-based deprivation and the effect of the Covid-19 pandemic: An analysis of mortality data across four nations (2023)
Journal Article
Leniz, J., Davies, J. M., Bone, A. E., Hocaoglu, M., Verne, J., Barclay, S., …Sleeman, K. E. (2023). Deaths at home, area-based deprivation and the effect of the Covid-19 pandemic: An analysis of mortality data across four nations. Palliative medicine, https://doi.org/10.1177/02692163231167212

Background: The number and proportion of home deaths in the UK increased during the Covid-19 pandemic. It is not known whether these changes were experienced disproportionately by people from different socioeconomic groups. Aim: To examine the associ... Read More about Deaths at home, area-based deprivation and the effect of the Covid-19 pandemic: An analysis of mortality data across four nations.

Using acoustic tracking of an anadromous lamprey in a heavily fragmented river to assess current and historic passage opportunities and prioritise remediation (2023)
Journal Article
Jubb, W. M., Noble, R. A., Dodd, J. R., Nunn, A. D., & Bolland, J. D. (in press). Using acoustic tracking of an anadromous lamprey in a heavily fragmented river to assess current and historic passage opportunities and prioritise remediation. River Research and Applications, https://doi.org/10.1002/rra.4140

Anthropogenic structures extensively fragment riverine systems, reducing longitudinal connectivity, inhibiting migration and leading to severe declines in many fish populations, especially for diadromous species. This study investigated the upstream... Read More about Using acoustic tracking of an anadromous lamprey in a heavily fragmented river to assess current and historic passage opportunities and prioritise remediation.

Inadequacy of fluvial energetics for describing gravity current autosuspension (2023)
Journal Article
Fukuda, S., de Vet, M. G., Skevington, E. W., Bastianon, E., Fernández, R., Wu, X., …Dorrell, R. M. (2023). Inadequacy of fluvial energetics for describing gravity current autosuspension. Nature communications, 14(1), Article 2288. https://doi.org/10.1038/s41467-023-37724-1

Gravity currents, such as sediment-laden turbidity currents, are ubiquitous natural flows that are driven by a density difference. Turbidity currents have provided vital motivation to advance understanding of this class of flows because their enigmat... Read More about Inadequacy of fluvial energetics for describing gravity current autosuspension.

The Readiness of Water Molecules to Split into Hydrogen + Oxygen: A Proposed New Aspect of Water Splitting (2023)
Journal Article
Schäfer, H., Schuster, A., Kunis, S., Bookholt, T., Hardege, J., Ruewe, K., & Brune, J. (in press). The Readiness of Water Molecules to Split into Hydrogen + Oxygen: A Proposed New Aspect of Water Splitting. Advanced materials, Article 2300099. https://doi.org/10.1002/adma.202300099

The potential of the anode, at which the evolution of oxygen begins, is a key parameter that describes how well water is split in water electrolyzers. Research efforts related to electrocatalytically initiated water splitting that aim at reducing the... Read More about The Readiness of Water Molecules to Split into Hydrogen + Oxygen: A Proposed New Aspect of Water Splitting.

Visual Attention to Dynamic Emotional Faces in Adults on the Autism Spectrum (2023)
Journal Article
Macinska, S., Lindsay, S., & Jellema, T. (2023). Visual Attention to Dynamic Emotional Faces in Adults on the Autism Spectrum. Journal of Autism and Developmental Disorders, https://doi.org/10.1007/s10803-023-05979-8

Using eye-tracking, we studied allocation of attention to faces where the emotional expression and eye-gaze dynamically changed in an ecologically-valid manner. We tested typically-developed (TD) adults low or high in autistic-like traits (Experiment... Read More about Visual Attention to Dynamic Emotional Faces in Adults on the Autism Spectrum.

Exercise and asthma – trigger or treatment? (2023)
Journal Article
Simpson, A. J., & Price, O. J. (2023). Exercise and asthma – trigger or treatment?. Respiratory medicine, 213, Article 107247. https://doi.org/10.1016/j.rmed.2023.107247

Exercise is one of the most commonly reported symptom triggers for people with asthma. However, a growing body of evidence indicates that regular exercise and physical activity are associated with improved clinical and patient reported outcomes. In t... Read More about Exercise and asthma – trigger or treatment?.

Economic and environmental conditions for the diffusion of insurance in three non-Euro-American regions during the nineteenth and twentieth centuries (2023)
Journal Article
Pearson, R., Daudi, F., Kocher, E., & Musterle, C. (in press). Economic and environmental conditions for the diffusion of insurance in three non-Euro-American regions during the nineteenth and twentieth centuries. Asia-Pacific Journal of Risk and Insurance, https://doi.org/10.1515/apjri-2022-0045

This paper discusses the macroeconomic and environmental conditions for the spread of insurance in three non-Western world regions (China, Middle East and sub-Sahara Africa). Focusing on the 19th and 20th centuries, it examines the patterns of econom... Read More about Economic and environmental conditions for the diffusion of insurance in three non-Euro-American regions during the nineteenth and twentieth centuries.

Capillary Assembly of Anisotropic Particles at Cylindrical Fluid-Fluid Interfaces (2023)
Journal Article
Eatson, J. L., Gordon, J. R., Cegielski, P., Giesecke, A. L., Suckow, S., Rao, A., …Buzza, D. M. A. (2023). Capillary Assembly of Anisotropic Particles at Cylindrical Fluid-Fluid Interfaces. Langmuir : the ACS journal of surfaces and colloids, 39(17), 6006–6017. https://doi.org/10.1021/acs.langmuir.3c00016

The unique behavior of colloids at liquid interfaces provides exciting opportunities for engineering the assembly of colloidal particles into functional materials. The deformable nature of fluid-fluid interfaces means that we can use the interfacial... Read More about Capillary Assembly of Anisotropic Particles at Cylindrical Fluid-Fluid Interfaces.

Evaporation of non-circular droplets (2023)
Journal Article
Wray, A., & Moore, M. (2023). Evaporation of non-circular droplets. Journal of Fluid Mechanics, 961, Article A11. https://doi.org/10.1017/jfm.2023.229

The dynamics of thin, non-circular droplets evaporating in the diffusion-limited regime is examined. The challenging non-rectilinear mixed boundary problem this poses is solved using a novel asymptotic approach and an asymptotic expansion for the eva... Read More about Evaporation of non-circular droplets.

Welfare Effects of Skills and Human Capital Development Policies in a DCGE Model of Ghana Article History (2023)
Journal Article
Bhattarai, K., & Okyere, E. (2023). Welfare Effects of Skills and Human Capital Development Policies in a DCGE Model of Ghana Article History. Journal of Development Economics and Finance, 4(1), 1-18. https://doi.org/10.47509/JDEF.2023.v04i01.01

Based on a 2012 Ghanaian social accounting matrix, we determined how different leisure levels and labour endowments affect household welfare and sectoral outputs. The findings of the leisure experiments point to a pattern in which the wellbeing impac... Read More about Welfare Effects of Skills and Human Capital Development Policies in a DCGE Model of Ghana Article History.