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All Outputs (3399)

Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer (2021)
Thesis
McKenzie, G. A. G. (2021). Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer. (Thesis). The University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4192792

Introduction: Older adults with cancer have worse outcomes than their younger counterparts, including higher postoperative complications, chemotherapy toxicity and treatment allocation to best supportive care. Oncogeriatric assessment (OGA) can provi... Read More about Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer.

Renewing approaches to understanding the minerals and waters at alkaline waste sites (2021)
Thesis
Bastianini, L. (2021). Renewing approaches to understanding the minerals and waters at alkaline waste sites. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224152

Highly alkaline (pH 9-12) waters can arise from a range of natural and anthropogenic processes. The latter include drainage waters from a range of globally significant anthropogenic by-products such as lime, cement and steel wastes, bauxite processin... Read More about Renewing approaches to understanding the minerals and waters at alkaline waste sites.

New routes to chiral-at-metal organometallic complexes and their application in asymmetric synthesis (2021)
Thesis
Shroot, S. (2021). New routes to chiral-at-metal organometallic complexes and their application in asymmetric synthesis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224096

This project develops new organometallic frameworks, to target the asymmetric transfer hydrogenation and hydrosilylation of ketones, aiming for enhanced activity and substrate scope relative to current state-of-the-art. The anticancer activity of som... Read More about New routes to chiral-at-metal organometallic complexes and their application in asymmetric synthesis.

Investigation of graphene oxide-based composite material strategies as possible candidates for leading edge erosion protection of offshore wind turbines (2021)
Thesis
Glanville, L. B. L. (2021). Investigation of graphene oxide-based composite material strategies as possible candidates for leading edge erosion protection of offshore wind turbines. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224240

At present the current climate and energy crisis has highlighted the global need for more renewable energy generation. Offshore wind provides a reliable source of this green energy however the harsh environments these assets operate in result in freq... Read More about Investigation of graphene oxide-based composite material strategies as possible candidates for leading edge erosion protection of offshore wind turbines.

Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia (2021)
Thesis
Naylor-Adamson, L. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4224129

Ibrutinib is highly effective in the treatment of chronic lymphocytic leukaemia (CLL), disrupting B cell receptor signalling through the inhibition of Bruton’s tyrosine kinase (Btk). However, ibrutinib has off-target effects, inhibiting platelet aggr... Read More about Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia.

Lab-on-a-chip platforms for pathogen analysis (2021)
Thesis
Rodriguez Mateos, P. (2021). Lab-on-a-chip platforms for pathogen analysis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224144

Infectious diseases caused by pathogenic microorganisms are a big burden in developed and developing countries. The emergence and rapid global spread of virus and antimicrobial resistant bacteria is a significant threat to patients, healthcare system... Read More about Lab-on-a-chip platforms for pathogen analysis.

Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor (2021)
Thesis
Plater, J. (2021). Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223832

The chemokine receptor CXCR4 has been shown to be over-expressed in multiple cancer types and is often linked to a poor prognosis, making it a significant target of interest for both imaging and therapeutics. Early diagnosis, imaging and identificati... Read More about Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor.

Sporopollenin : applications in water purification (2021)
Thesis
Meichanetzoglou, A. (2021). Sporopollenin : applications in water purification. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223849

Water pollution from emerging contaminants is increasingly in the spotlight, as research on the impacts on the environment is revealing more about the dangers to both animals in the aquatic environment and human health. Pharmaceuticals, personal care... Read More about Sporopollenin : applications in water purification.

Yorkshire’s folk culture in digital spaces during the COVID-19 pandemic : cultural practice, digitalisation and localisation (2021)
Thesis
Sewell, C. T. (2021). Yorkshire’s folk culture in digital spaces during the COVID-19 pandemic : cultural practice, digitalisation and localisation. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224009

This thesis critically assesses the digital spaces where Yorkshire’s folk community practiced sonic and material cultures and developed identities of communal belonging during the initial phase of the COVID-19 pandemic. Using data gathered throughout... Read More about Yorkshire’s folk culture in digital spaces during the COVID-19 pandemic : cultural practice, digitalisation and localisation.

Evidence of herding behaviour in stock markets (2021)
Thesis
Wang, J. (2021). Evidence of herding behaviour in stock markets. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224272

This thesis investigates herding behaviour among major world stock markets from 2002 to 2018. It also studies the herding behaviour at sector level from 2001 to 2020. In the first chapter, we introduce the background and motivation for this study. In... Read More about Evidence of herding behaviour in stock markets.

Mechanochemical ablation in the treatment of superficial venous incompetence (2021)
Thesis
Mohamed, A. (2021). Mechanochemical ablation in the treatment of superficial venous incompetence. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4223528

Background The routine management of venous incompetence has undergone considerable changes in the last two decades led by the introduction of minimally invasive endovenous techniques. At the heart of these changes has been a drive to offer patients... Read More about Mechanochemical ablation in the treatment of superficial venous incompetence.

The need for epistemic reciprocity in person-centred care : a multi-method qualitative study (2021)
Thesis
Dell’Olio, M. (2021). The need for epistemic reciprocity in person-centred care : a multi-method qualitative study. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4224117

Background – Person-centred care is a policy priority in the United Kingdom, yet people with long-term conditions report a deficiency in person-centred healthcare relative to their wishes and expectations. Whilst several factors contribute to this pr... Read More about The need for epistemic reciprocity in person-centred care : a multi-method qualitative study.

An examination of the motivations for the foreign acquisitions of the local banks : a case study of the Egyptian banks (2021)
Thesis
Abdel-Aziz, H. A. M. (2021). An examination of the motivations for the foreign acquisitions of the local banks : a case study of the Egyptian banks. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223512

Opposite to the 1970s, 1980s, 1990s, where there were several foreign banks joint ventures and branches of foreign banks established; the initial years of 2000s, in particular, between 2005-2010, had witnessed of established a wave of foreign banks M... Read More about An examination of the motivations for the foreign acquisitions of the local banks : a case study of the Egyptian banks.

Quantitative morphology of galaxy clusters at X-ray wavelengths (2021)
Thesis
Hunt, L. (2021). Quantitative morphology of galaxy clusters at X-ray wavelengths. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224267

We apply quantitative morphology techniques to X-ray imaging of clusters of galaxies to determine correlation between calculated parameters (CAS, Gini and M20) and features such as bow shocks, cold fronts, gas sloshing, Kelvin-Helmholtz instabilities... Read More about Quantitative morphology of galaxy clusters at X-ray wavelengths.

Investigation of the regulatory role of CBX2 in breast cancer via in silico transcriptomic analysis and in vitro cistromic analysis (2021)
Thesis
Kalsi, S. C. (2021). Investigation of the regulatory role of CBX2 in breast cancer via in silico transcriptomic analysis and in vitro cistromic analysis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224331

Chromobox 2 (CBX2) is a component of Polycomb repressive protein complex 1 (PRC1), which is an epigenetic regulatory complex that downregulates the expression of target genes. CBX2 has been linked to cancer progression and development in several canc... Read More about Investigation of the regulatory role of CBX2 in breast cancer via in silico transcriptomic analysis and in vitro cistromic analysis.

The nature of novel word representations : computer mouse tracking shows evidence of immediate lexical engagement effects in adults (2021)
Thesis
Lucas, A. P. (2021). The nature of novel word representations : computer mouse tracking shows evidence of immediate lexical engagement effects in adults. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223534

Simplistically, words are the mental bundling of a form and a referent. However, words also dynamically interact with one another in the cognitive system, and have other so-called ‘lexical properties’. For example, the word ‘dog’ will cue recognition... Read More about The nature of novel word representations : computer mouse tracking shows evidence of immediate lexical engagement effects in adults.

The effect of future thinking and emotion on false memory formation (2021)
Thesis
Vella, G. (2021). The effect of future thinking and emotion on false memory formation. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223860

Research has found that future thinking increases the number of false memories formed when compared to thinking about the past (Dewhurst et al., 2016; Dewhurst et al., 2019). Previous research, however, has not controlled for emotional valence. There... Read More about The effect of future thinking and emotion on false memory formation.

Vaccination timeliness in preterm infants (2021)
Thesis
Sisson, H. (2021). Vaccination timeliness in preterm infants. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223855

Background Vaccination is a key public health activity, with established programmes primarily aimed at infants and children. Infants born prematurely are particularly vulnerable to infection, therefore the protection vaccination offers these infants... Read More about Vaccination timeliness in preterm infants.