All Outputs (828)

Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain (2010)
Journal Article
Simpson, J. E., Ince, P. G., Haynes, L. J., Theaker, R., Gelsthorpe, C., Baxter, L., …Wharton, S. B. (2010). Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain. Neuropathology and Applied Neurobiology, 36(1), 25-40. https://doi.org/10.1111/j.1365-2990.2009.01030.x

Aims: Increasing evidence suggests a role for oxidative damage to DNA in brain ageing and in neurodegenerative disorders, including Alzheimer's disease. Most studies have focussed on the reduced capacity for DNA repair by neurones, and have not taken... Read More about Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain.

Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review (2010)
Journal Article
Johnson, M. J., Oxberry, S. G., Cleland, J. G., & Clark, A. L. (2010). Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review. European journal of heart failure, 12(2), 137-147. https://doi.org/10.1093/eurjhf/hfp194

AIMS: Chronic breathlessness is a major symptom for patients with compensated chronic heart failure (CHF) and its impact is different to the breathlessness resulting from pulmonary oedema. This systematic review aims to establish which tools have bee... Read More about Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review.

An 80 million year oceanic redox history from Permian to Jurassic pelagic sediments of the Mino-Tamba terrane, SW Japan, and the origin of four mass extinctions (2010)
Journal Article
Wignall, P. B., Bond, D. P., Kuwahara, K., Kakuwa, Y., Newton, R. J., & Poulton, S. W. (2010). An 80 million year oceanic redox history from Permian to Jurassic pelagic sediments of the Mino-Tamba terrane, SW Japan, and the origin of four mass extinctions. Global and planetary change, 71(1-2), 109-123. https://doi.org/10.1016/j.gloplacha.2010.01.022

Fabric and pyrite framboid size analysis of Permian to Jurassic samples from the Mino-Tamba terrane of Japan provide an 80myr redox history from the Panthalassa Ocean. Fully oxygenated conditions dominated but were punctuated by three phases of anoxi... Read More about An 80 million year oceanic redox history from Permian to Jurassic pelagic sediments of the Mino-Tamba terrane, SW Japan, and the origin of four mass extinctions.

KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming (2010)
Journal Article
Hansen, A., Henderson, S., Lagos, D., Nikitenko, L., Coulter, E., Roberts, S., Gratrix, F., Plaisance, K., Renne, R., Bower, M., Kellam, P., & Boshoff, C. (2010). KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. Genes & development, 24(2), 195-205. https://doi.org/10.1101/gad.553410

Kaposi sarcoma herpesvirus (KSHV) induces transcriptional reprogramming of endothelial cells. In particular, KSHV-infected lymphatic endothelial cells (LECs) show an up-regulation of genes associated with blood vessel endothelial cells (BECs). Conseq... Read More about KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming.

Shearing particle monolayers: Strain-rate frequency superposition (2010)
Journal Article
Zang, D., Langevin, D., Binks, B. P., & Wei, B. (2010). Shearing particle monolayers: Strain-rate frequency superposition. Physical review. E, Statistical, nonlinear, and soft matter physics, 81(1), 011604. https://doi.org/10.1103/PhysRevE.81.011604

We report surface shear rheological measurements on monolayers of silica nanoparticles at the air-water interface. We have used the method of strain-rate frequency superposition (SRFS) to characterize the structural relaxation. We show that the rheol... Read More about Shearing particle monolayers: Strain-rate frequency superposition.

Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies (2010)
Journal Article
Alonso, C. M. A., Palumbo, A., Bullous, A. J., Pretto, F., Neri, D., & Boyle, R. W. (2010). Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies. Bioconjugate chemistry, 21(2), 302-313. https://doi.org/10.1021/bc9003537

Synthesis of three new cationic thiol-reactive maleimide-porphyrin derivatives and their use in site-specific conjugation to monoclonal antibodies is reported. The selective reactivity toward thiols is demonstrated using competition experiments, wher... Read More about Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies.

Understanding the international student experience (2010)
Book
Montgomery, C. (2010). Understanding the international student experience. Palgrave Macmillan

Presents a contemporary approach to the experience of international students in Higher Education. Using empirical and qualitative data, the book explores their social and cultural context and its impact on their learning experience.

Metal catalysts for ε-caprolactone polymerisation (2010)
Journal Article
Arbaoui, A., & Redshaw, C. (2010). Metal catalysts for ε-caprolactone polymerisation. Polymer chemistry, 1(6), 801-826. https://doi.org/10.1039/b9py00334g

Economic pressure, environmental issues and ever increasing demand are driving the shift from oil-based polymers to those available from renewable resources. Ring opening polymerisation of cyclic esters is currently a topical field with metal complex... Read More about Metal catalysts for ε-caprolactone polymerisation.

Developing integrated rural tourism : actor practices in the English/Welsh border (2010)
Journal Article
Saxena, G., & Ilbery, B. (2010). Developing integrated rural tourism : actor practices in the English/Welsh border. Journal of rural studies, 26(3), 260-271. https://doi.org/10.1016/j.jrurstud.2009.12.001

This paper examines community attitudes and distinctive practices that shape local responses to integrated rural tourism (IRT) development in the lagging rural region of the English/Welsh border area. The focus is on how actors acquire attributes as... Read More about Developing integrated rural tourism : actor practices in the English/Welsh border.

Risk factors for severe child poverty in the UK (2010)
Journal Article
Magadi, M. (2010). Risk factors for severe child poverty in the UK. Journal of Social Policy, 39(2), 297-316. https://doi.org/10.1017/S0047279409990651

Despite recent declines in child poverty in the UK, there is evidence that children from the poorest families remain a legitimate concern. Little is known about the circumstances of children in severe poverty for whom policy responses may need to be... Read More about Risk factors for severe child poverty in the UK.

How the human brain recognizes speech in the context of changing speakers (2010)
Journal Article
Von Kriegstein, K., Smith, D. R., Patterson, R. D., Kiebel, S. J., & Griffiths, T. D. (2010). How the human brain recognizes speech in the context of changing speakers. Journal of Neuroscience, 30(2), 629-638. https://doi.org/10.1523/JNEUROSCI.2742-09.2010

We understand speech from different speakers with ease, whereas artificial speech recognition systems struggle with this task. It is unclear how the human brain solves this problem. The conventional view is that speech message recognition and speaker... Read More about How the human brain recognizes speech in the context of changing speakers.

Desymmetrisation of (4R,5S)-4,5-diphenylimidazolidine-2-thione using pentafluorophenyl active esters (2010)
Journal Article
Andreou, A., Eames, J., Motevalli, M., Prior, T. J., & Watkinson, M. (2010). Desymmetrisation of (4R,5S)-4,5-diphenylimidazolidine-2-thione using pentafluorophenyl active esters. Tetrahedron letters; the international organ for the rapid publication of preliminary communications in organic chemistry, 51(10), 1423-1425. https://doi.org/10.1016/j.tetlet.2010.01.019

(4R,5S)-4,5-Diphenylimidazolidine-2-thione is efficiently desymmetrised by stereorandom deprotonation with NaHMDS, followed by kinetic resolution of the resulting racemic intermediate with an enantiomerically pure pentafluorophenyl active ester. The... Read More about Desymmetrisation of (4R,5S)-4,5-diphenylimidazolidine-2-thione using pentafluorophenyl active esters.

Fitness for practice in nursing and midwifery education in Scotland, United Kingdom (2010)
Journal Article
Holland, K., Roxburgh, M., Johnson, M., Topping, K., Watson, R., Lauder, W., & Porter, M. (2010). Fitness for practice in nursing and midwifery education in Scotland, United Kingdom. Journal of clinical nursing, 19(3-4), 461-469. https://doi.org/10.1111/j.1365-2702.2009.03056.x

Aim. The aim of this paper is to report findings from a major study that evaluated the Fitness for Practice nursing and midwifery curriculum in Scotland, UK. Background. The competence of student nurses and midwives at the point of registration has b... Read More about Fitness for practice in nursing and midwifery education in Scotland, United Kingdom.

The optical properties of hybrid organic-inorganic L3 nanocavities (2010)
Journal Article
Murshidy, M. M., Adawi, A. M., Fry, P. W., Whittaker, D. M., & Lidzey, D. G. (2010). The optical properties of hybrid organic-inorganic L3 nanocavities. Journal of the Optical Society of America B, 27(2), 215-221. https://doi.org/10.1364/JOSAB.27.000215

We report the fabrication of L3 nanocavities defined into a free-standing silicon nitride (SiN) membrane coated with a thin (10 nm) film of fluorescent red-emitting conjugated polymer. We find that structures both with and without the conjugated poly... Read More about The optical properties of hybrid organic-inorganic L3 nanocavities.

Falling Through Clouds (2010)
Book
Chilvers, A. (2010). Falling Through Clouds. Hebden Bridge: Bluemoose Books

Kat, a 22 year-old student, returning home to Devon for the summer holidays meets Gavin on the train. They spend the summer in Cornwall but he has something on his mind. He is plagued with nightmares after having been held hostage in Iraq and she soo... Read More about Falling Through Clouds.

Amino acid metabolism of bovine blastocysts: A biomarker of sex and viability (2010)
Journal Article
Sturmey, R. G., Bermejo-Alvarez, P., Gutierrez-Adan, A., Rizos, D., Leese, H. J., & Lonergan, P. (2010). Amino acid metabolism of bovine blastocysts: A biomarker of sex and viability. Molecular Reproduction and Development, 77(3), 285-296. https://doi.org/10.1002/mrd.21145

The ratio of male/female embryos may be modified by environmental factors such as maternal diet in vivo and the composition of embryo culture media in vitro. We have used amino acid profiling, a noninvasive marker of developmental potential to compar... Read More about Amino acid metabolism of bovine blastocysts: A biomarker of sex and viability.

Using spaced retrieval and Montessori-based activities in improving eating ability for residents with dementia (2010)
Journal Article
Lin, L.-C., Huang, Y.-J., Su, S.-G., Watson, R., Tsai, B. W.-J., & Wu, S.-C. (2010). Using spaced retrieval and Montessori-based activities in improving eating ability for residents with dementia. International journal of geriatric psychiatry, 25(10), 953-959. https://doi.org/10.1002/gps.2433

Objectives To construct a training protocol for spaced retrieval (SR) and to investigate the effectiveness of SR and Montessori-based activities in decreasing eating difficulty in older residents with dementia. Methods A single evaluator, blind, and... Read More about Using spaced retrieval and Montessori-based activities in improving eating ability for residents with dementia.

Behavioural consequences of sensory plasticity in guppies (2010)
Journal Article
Chapman, B. B., Morrell, L. J., Tosh, C. R., & Krause, J. (2010). Behavioural consequences of sensory plasticity in guppies. Proceedings of the Royal Society B: Biological Sciences, 277(1686), 1395-1401. https://doi.org/10.1098/rspb.2009.2055

Sensory plasticity, whereby individuals compensate for sensory deprivation in one sense by an improvement in the performance of an alternative sense, is a well-documented phenomenon in nature. Despite this, the behavioural and ecological consequences... Read More about Behavioural consequences of sensory plasticity in guppies.

Modeling the deposition dynamics of a twin-atomizer spray forming system (2010)
Journal Article
Zhang, G., Li, Z., Zhang, Y., Mi, J., & Grant, P. S. (2010). Modeling the deposition dynamics of a twin-atomizer spray forming system. Metallurgical and Materials Transactions B, 41(2), 303-307. https://doi.org/10.1007/s11663-009-9333-0

A numerical study of the deposition dynamics of twin-atomizer spray-forming of large-diameter billets is presented with a focus on the coupled effect of the twinatomizer scan frequency and substrate rotation frequency. The common period of the two fr... Read More about Modeling the deposition dynamics of a twin-atomizer spray forming system.

Enhancing medication adherence in people with schizophrenia: an international programme of research (2010)
Journal Article
Gray, R., White, J., Schulz, M., & Abderhalden, C. (2010). Enhancing medication adherence in people with schizophrenia: an international programme of research. International Journal of Mental Health Nursing, 19(1), 36-44. https://doi.org/10.1111/j.1447-0349.2009.00649.x

This paper describes the development of an adherence therapy intervention in schizophrenia and synthesizes the results to date of a collaborative international programme of research. Sticking to treatment is essential to control symptoms and prevent... Read More about Enhancing medication adherence in people with schizophrenia: an international programme of research.