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All Outputs (1098)

Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia (2021)
Thesis
Naylor-Adamson, L. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4224129

Ibrutinib is highly effective in the treatment of chronic lymphocytic leukaemia (CLL), disrupting B cell receptor signalling through the inhibition of Bruton’s tyrosine kinase (Btk). However, ibrutinib has off-target effects, inhibiting platelet aggr... Read More about Bruton’s tyrosine kinase inhibitors impair FcγRIIa-mediated platelet responses to bacteria in chronic lymphocytic leukaemia.

Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor (2021)
Thesis
Plater, J. (2021). Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223832

The chemokine receptor CXCR4 has been shown to be over-expressed in multiple cancer types and is often linked to a poor prognosis, making it a significant target of interest for both imaging and therapeutics. Early diagnosis, imaging and identificati... Read More about Development of fluorine-18 radiolabelled peptides for targeted imaging of the CXCR4 chemokine receptor.

On sound propagation along an infinite rectangular duct-like structure with a finite slot opening and its modelling (2021)
Journal Article
Chu, S. H., & Tang, S. K. (2021). On sound propagation along an infinite rectangular duct-like structure with a finite slot opening and its modelling. The Journal of the Acoustical Society of America, 150(5), 3445-3460. https://doi.org/10.1121/10.0007061

The sound propagation across a sound leaking section along an infinite rectangular duct-like structure near to the lower order duct eigenfrequencies is investigated numerically in the present study. The sound leakage is achieved by finite length rect... Read More about On sound propagation along an infinite rectangular duct-like structure with a finite slot opening and its modelling.

Quantitative Methodology, Positivist Philosophy and Disciplinary Subjectivity: Indigenisation of British Sociology and Lessons for Chinese Sociology (2021)
Journal Article
Wang, C. (2021). Quantitative Methodology, Positivist Philosophy and Disciplinary Subjectivity: Indigenisation of British Sociology and Lessons for Chinese Sociology. Journal of Social Development, 2021(4), 215-243

英国社会学在本土化历程中形成了鲜明的反量化取向和通识学科定位，这影响了其学科风格。本文追溯了两个知识传统对这一学科风格的影响：一是英国本土知识传统——统计学传统，它以“不介入”的方式成为英国社会学的主要他者；另一是孔德的实证哲学和社会学观念，它成为二战前... Read More about Quantitative Methodology, Positivist Philosophy and Disciplinary Subjectivity: Indigenisation of British Sociology and Lessons for Chinese Sociology.

Publishing a Special Issue of Reports from the volcano observatories in Latin America (2021)
Journal Article
Chevrel, O., Wadsworth, F. B., Farquharson, J. I., Kushnir, A. R., Heap, M. J., Williams, R., …Kennedy, B. (2021). Publishing a Special Issue of Reports from the volcano observatories in Latin America. Volcanica, 4(S1), I-III. https://doi.org/10.30909/vol.04.S1.ivi

Peer-reviewed publications are the most common way of sharing scientific knowledge internationally. Volcanica is the only fully diamond open access journal in volcanology, publishing peer-reviewed articles without costs to authors or readers. As part... Read More about Publishing a Special Issue of Reports from the volcano observatories in Latin America.

COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study (2021)
Journal Article
Chatzikonstantinou, T., Kapetanakis, A., Scarfò, L., Karakatsoulis, G., Allsup, D., Cabrero, A. A., Andres, M., Antic, D., Baile, M., Baliakas, P., Bron, D., Capasso, A., Chatzileontiadou, S., Cordoba, R., Correa, J. G., Cuéllar-García, C., De Paoli, L., De Paolis, M. R., Del Poeta, G., Demosthenous, C., …Ghia, P. (in press). COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, https://doi.org/10.1038/s41375-021-01450-8

Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to Coronavirus disease 2019 (COVID-19) due to age, disease, and treatment-related immunosuppression. We aimed to assess risk factors of outcome and elucidate the impact of CLL-d... Read More about COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study.

Lessons from peace negotiations: interview with Ehud Olmert (2021)
Journal Article
Cohen-Almagor, R. (2021). Lessons from peace negotiations: interview with Ehud Olmert. Israel affairs, 27(6), 1160-1189. https://doi.org/10.1080/13537121.2021.1993000

Israeli PM Ehud Olmert (2006–9) offered the Palestinians the most comprehensive peace deal they had ever received. Palestinian Authority President Mahmoud Abbas said he would reply ‘soon’ and never did. This interview records Olmert’s thoughts on the... Read More about Lessons from peace negotiations: interview with Ehud Olmert.

Robust fuzzy sliding mode controller for a skid-steered vehicle subjected to friction variations (2021)
Journal Article
Mehmood, Y., Aslam, J., Ullah, N., Alsheikhy, A. A., Din, E. U., & Iqbal, J. (2021). Robust fuzzy sliding mode controller for a skid-steered vehicle subjected to friction variations. PLoS ONE, 16(11), Article 0258909. https://doi.org/10.1371/journal.pone.0258909

Skid-steered vehicles (SSV) are gaining huge importance in the market due to their applications like construction, agricultural work, material handling etc. The accuracy of performing such tasks require a robust control algorithm. The design of such... Read More about Robust fuzzy sliding mode controller for a skid-steered vehicle subjected to friction variations.

Unscented Kalman filter for airship model uncertainties and wind disturbance estimation (2021)
Journal Article
Wasim, M., Ali, A., Ahmad Choudhry, M., Saleem, F., Shaikh, I. U. H., & Iqbal, J. (2021). Unscented Kalman filter for airship model uncertainties and wind disturbance estimation. PLoS ONE, 16(11 November), Article e0257849. https://doi.org/10.1371/journal.pone.0257849

An airship is lighter than an air vehicle with enormous potential in applications such as communication, aerial inspection, border surveillance, and precision agriculture. An airship model is made up of dynamic, aerodynamic, aerostatic, and propulsiv... Read More about Unscented Kalman filter for airship model uncertainties and wind disturbance estimation.

An ABAQUS® plug-in for generating virtual data required for inverse analysis of unidirectional composites using artificial neural networks (2021)
Journal Article
Ismail, Y., Wan, L., Chen, J., Ye, J., & Yang, D. (2022). An ABAQUS® plug-in for generating virtual data required for inverse analysis of unidirectional composites using artificial neural networks. Engineering with Computers, 38(5), 4323-4335. https://doi.org/10.1007/s00366-021-01525-1

This paper presents a robust ABAQUS® plug-in called Virtual Data Generator (VDGen) for generating virtual data for identifying the uncertain material properties in unidirectional lamina through artificial neural networks (ANNs). The plug-in supports... Read More about An ABAQUS® plug-in for generating virtual data required for inverse analysis of unidirectional composites using artificial neural networks.

Rethinking Fake News: Disinformation and Ideology during the time of COVID-19 Global Pandemic (2021)
Journal Article
Das, R., & Ahmed, W. (2021). Rethinking Fake News: Disinformation and Ideology during the time of COVID-19 Global Pandemic. IIM Kozhikode Society & Management Review, 11(1), 146-159. https://doi.org/10.1177/22779752211027382

Digital media and citizen journalism has escalated the infiltration of fake news attempting to create a post truth society (Lazer et al., 2018). The COVID-19 pandemic has seen a surge of misinformation leading to anti-mask, anti-vaccine and anti-5G p... Read More about Rethinking Fake News: Disinformation and Ideology during the time of COVID-19 Global Pandemic.

Intended and unintended consequences of the implementation of minimum unit pricing of alcohol in Scotland: a natural experiment (2021)
Journal Article
So, V., Millard, A. D., Katikireddi, S. V., Forsyth, R., Allstaff, S., Deluca, P., …Leyland, A. H. (2021). Intended and unintended consequences of the implementation of minimum unit pricing of alcohol in Scotland: a natural experiment. Public Health Research, 9(11), 1-210. https://doi.org/10.3310/phr09110

Abstract
Background
Scotland was the first country to implement minimum unit pricing for alcohol nationally. Minimum unit pricing aims to reduce alcohol-related harms and to narrow health inequalities. Minimum unit pricing sets a minimum retail pri... Read More about Intended and unintended consequences of the implementation of minimum unit pricing of alcohol in Scotland: a natural experiment.

‘We'd never had to set up a virtual school before’: Opportunities and challenges for primary and secondary teachers during emergency remote education (2021)
Journal Article
Gouseti, A. (2021). ‘We'd never had to set up a virtual school before’: Opportunities and challenges for primary and secondary teachers during emergency remote education. Review of Education, 9(3), Article e3305. https://doi.org/10.1002/rev3.3305

The Covid-19 pandemic has brought about the largest disruption to formal education in recent history and has resulted in school closures and the move to online teaching and learning across the globe. Using data from interviews with 25 teachers and he... Read More about ‘We'd never had to set up a virtual school before’: Opportunities and challenges for primary and secondary teachers during emergency remote education.

Synthesis and analysis of small molecules to restrain the function of tissue factor within tumour cells (2021)
Journal Article
Adeniran, O. I., Mohammad, M. A., Featherby, S., Maraveyas, A., Boa, A. N., & Ettelaie, C. (2021). Synthesis and analysis of small molecules to restrain the function of tissue factor within tumour cells. Frontiers in Bioscience-Landmark, 26(10), 752-764. https://doi.org/10.52586/4985

Introduction: The restriction of prolyl-protein cis/trans isomerase 1 (Pin1) activity has been shown to prevent the release of tissue factor (TF) leading to the accumulation of the latter protein within the cell. This study tested the ability of nove... Read More about Synthesis and analysis of small molecules to restrain the function of tissue factor within tumour cells.

Galaxy and mass assembly (GAMA): The merging potential of brightest group galaxies (2021)
Journal Article
Banks, K., Brough, S., Holwerda, B. W., Hopkins, A. M., López-Sánchez, R., Phillipps, S., …Robotham, A. S. (2021). Galaxy and mass assembly (GAMA): The merging potential of brightest group galaxies. The Astrophysical journal, 921(1), 9. https://doi.org/10.3847/1538-4357/ac1c0a

Using a volume-limited sample of 550 groups from the Galaxy And Mass Assembly Galaxy Group Catalogue spanning the halo mass range 12.8 < log[Mh M?] < 14.2, we investigate the merging potential of central Brightest Group Galaxies (BGGs). We use spectr... Read More about Galaxy and mass assembly (GAMA): The merging potential of brightest group galaxies.

Impact of pharmacological interventions on insulin resistance in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials (2021)
Journal Article
Abdalla, M. A., Shah, N., Deshmukh, H., Sahebkar, A., Östlundh, L., Al-Rifai, R. H., …Sathyapalan, T. (in press). Impact of pharmacological interventions on insulin resistance in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials. Clinical Endocrinology, https://doi.org/10.1111/cen.14623

Objective: Polycystic ovary syndrome (PCOS) is a complex endocrine condition affecting women of reproductive age. It is characterized by insulin resistance and is a major risk factor for type 2 diabetes mellitus (T2DM). The objective was to review th... Read More about Impact of pharmacological interventions on insulin resistance in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials.

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (2021)
Journal Article
Lin, W. Y., Fordham, S. E., Hungate, E., Sunter, N. J., Elstob, C., Xu, Y., …Allan, J. M. (2021). Genome-wide association study identifies susceptibility loci for acute myeloid leukemia. Nature communications, 12(1), Article 6233. https://doi.org/10.1038/s41467-021-26551-x

Acute myeloid leukemia (AML) is a hematological malignancy with an undefined heritable risk. Here we perform a meta-analysis of three genome-wide association studies, with replication in a fourth study, incorporating a total of 4018 AML cases and 104... Read More about Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.

Domestic dogs (Canis lupus familiaris) are sensitive to the correlation between pitch and timbre in human speech (2021)
Journal Article
Sturdy, S., Smith, D. R., & George, D. N. (in press). Domestic dogs (Canis lupus familiaris) are sensitive to the correlation between pitch and timbre in human speech. Animal Cognition, https://doi.org/10.1007/s10071-021-01567-4

The perceived pitch of human voices is highly correlated with the fundamental frequency (f0) of the laryngeal source, which is determined largely by the length and mass of the vocal folds. The vocal folds are larger in adult males than in adult femal... Read More about Domestic dogs (Canis lupus familiaris) are sensitive to the correlation between pitch and timbre in human speech.

Anti-inflammation and antimalarial profile of 5-pyridin-2-yl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester as a low molecular intermediate for hybrid drug synthesis (2021)
Journal Article
Eya’ane Meva, F., Prior, T. J., Evans, D. J., Shah, S., Tamngwa, C. F., Belengue, H. G. L., …Llinás, M. (2022). Anti-inflammation and antimalarial profile of 5-pyridin-2-yl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester as a low molecular intermediate for hybrid drug synthesis. Research on Chemical Intermediates, 48(2), 885–898. https://doi.org/10.1007/s11164-021-04607-3

A novel 1,2,4-triazole intermediate 5-pyridin-2-yl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester was prepared by the reaction of N’-aminopiridyne-2-carboximidamine and an excess monoethyl oxalyl chloride and screened for biological activities. The... Read More about Anti-inflammation and antimalarial profile of 5-pyridin-2-yl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester as a low molecular intermediate for hybrid drug synthesis.