Professor Michael Lind's Outputs (12)

Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction (2024)
Thesis
Patterson, M. J. Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4711450

Background: Malignant bowel obstruction (MBO) is a distressing complication of gastrointestinal, gynaecological and other cancers causing severe pain, intractable nausea and vomiting, anorexia, and death. There are no agreed best approaches for sympt... Read More about Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction.

Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction (2024)
Thesis
Patterson, M. J. Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4790741

Background: Malignant bowel obstruction (MBO) is a distressing complication of gastrointestinal, gynaecological and other cancers causing severe pain, intractable nausea and vomiting, anorexia, and death. There are no agreed best approaches for sympt... Read More about Parenteral nutrition and venting gastrostomy in the management of malignant bowel obstruction.

Determination of epithelial growth factor receptor mutations in circulatory tumour cells from non-small cell lung cancer patients isolated using a novel microfluidic device (2022)
Thesis
Ogidi, N. O. Determination of epithelial growth factor receptor mutations in circulatory tumour cells from non-small cell lung cancer patients isolated using a novel microfluidic device. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4270004

Patients with epidermal growth factor receptor (EGFR) sensitizing mutations in non small cell lung cancer (NSCLC) receive benefit from Tyrosine Kinase inhibitors. Accurate selection of patients before treatment is highly dependent on precise molecula... Read More about Determination of epithelial growth factor receptor mutations in circulatory tumour cells from non-small cell lung cancer patients isolated using a novel microfluidic device.

The detection and assessment of malnutrition, sarcopenia and cachexia, in older adults with cancer (2022)
Thesis
Bullock, A. F. The detection and assessment of malnutrition, sarcopenia and cachexia, in older adults with cancer. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4484119

Background: Older adults with cancer are a complex and growing population requiring tailored care to achieve optimum treatment outcomes. However, their care is complicated by underrecognised
and under-treated nutrition-related wasting disorders: mal... Read More about The detection and assessment of malnutrition, sarcopenia and cachexia, in older adults with cancer.

Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer (2021)
Thesis
McKenzie, G. A. G. Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer. (Thesis). The University of Hull and the University of York. https://hull-repository.worktribe.com/output/4192792

Introduction: Older adults with cancer have worse outcomes than their younger counterparts, including higher postoperative complications, chemotherapy toxicity and treatment allocation to best supportive care. Oncogeriatric assessment (OGA) can provi... Read More about Developing an evidence-based system to facilitate the predictive assessment and optimisation of older adults with cancer.

EGFR and related therapeutic targets in malignant pleural mesothelioma (2016)
Thesis
Oguh, L. I. EGFR and related therapeutic targets in malignant pleural mesothelioma. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4221787

Introduction
Malignant pleural mesothelioma (MPM) is a rare but aggressive disease and the current first line treatment is associated with a survival rate of 40%. There is currently no second line therapy. This study aimed to explore the expression... Read More about EGFR and related therapeutic targets in malignant pleural mesothelioma.

Investigating the role of microRNA-31 as a modulator of chemosensitivity in malignant leural mesothelioma (2016)
Thesis
Moody, H. L. Investigating the role of microRNA-31 as a modulator of chemosensitivity in malignant leural mesothelioma. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4219227

Malignant pleural mesothelioma (MPM) is associated with an extremely poor prognosis and the majority of patients are initially or rapidly become unresponsive to platinum-based chemotherapy. MicroRNA-31 (miR-31) is encoded on a genomic fragile site, 9... Read More about Investigating the role of microRNA-31 as a modulator of chemosensitivity in malignant leural mesothelioma.

Proteomic identification of putative biomarkers of radiotherapy resistance (2012)
Thesis
Scaife, L. Proteomic identification of putative biomarkers of radiotherapy resistance. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4214086

Background
Currently, tumour response to radiotherapy cannot be predicted meaning that those patients with tumours resistant to the therapy endure the harmful side effects associated with ionising radiation in the absence of therapeutic gain. The ai... Read More about Proteomic identification of putative biomarkers of radiotherapy resistance.

Proteomic identification and validation of biomarkers associated with resistance to radiotherapy in breast cancer (2012)
Thesis
ElFadl, D. Proteomic identification and validation of biomarkers associated with resistance to radiotherapy in breast cancer. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4218629

Background:
Breast cancer is an important health issue. The majority of patients present with early stage cancer and are therefore candidates for breast conserving surgery and radiotherapy. A proportion will suffer from local recurrence, which may b... Read More about Proteomic identification and validation of biomarkers associated with resistance to radiotherapy in breast cancer.

The significance of the EGFR pathway in malignant pleural mesothelioma (2012)
Thesis
Agarwal, V. (. The significance of the EGFR pathway in malignant pleural mesothelioma. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4214047

Introduction
EGFR, MTOR and COX2 are up regulated in malignant pleural mesothelioma (MPM). In this study we aimed to determine the expression of Lipoxygenase enzymes (LOX), absence of PTEN protein expression and the cytotoxic effect of EGFR, MTOR an... Read More about The significance of the EGFR pathway in malignant pleural mesothelioma.

The identification of biomarkers of chemotherapy resistance in breast cancer using comparative proteomics (2011)
Thesis
Hodgkinson, V. C. The identification of biomarkers of chemotherapy resistance in breast cancer using comparative proteomics. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4211852

Background:Chemotherapy resistance is a major obstacle in effective neoadjuvant treatment for locally advanced breast cancer. The ability to predict tumour response would allow chemotherapy administration to be directed towards only those patients wh... Read More about The identification of biomarkers of chemotherapy resistance in breast cancer using comparative proteomics.

The proteomic analysis of resistance to anticancer therapy in human breast cancer (2006)
Thesis
Smith, L. The proteomic analysis of resistance to anticancer therapy in human breast cancer. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4212607

Resistance to anticancer therapy represents a major barrier in the successful management of human breast cancer. The identification of novel biomarkers that correlate with treatment response would increase our understanding of the resistance mechanis... Read More about The proteomic analysis of resistance to anticancer therapy in human breast cancer.