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SOCS VASC - Stabilising suppressor of cytokine signalling 3 (SOCS3) to limit vascular re-modelling in vein graft failure and in-stent restenosis

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Dr James Hobkirk J.Hobkirk@hull.ac.uk
Lecturer in Physiology & Pathophysiology & Honorary Medical Scientist

Do T2DM and Hyperglycaemia Affect the Expression Levels of the Regulating Enzymes of Cellular O-GlcNAcylation in Human Saphenous Vein Smooth Muscle Cells? (2024)
Journal Article
Bolanle, I. O., Durham, G., Hobkirk, J. P., Loubani, M., Sturmey, R. G., & Palmer, T. M. (2024). Do T2DM and Hyperglycaemia Affect the Expression Levels of the Regulating Enzymes of Cellular O-GlcNAcylation in Human Saphenous Vein Smooth Muscle Cells?. Diabetology, 5(2), 162-177. https://doi.org/10.3390/diabetology5020013

Protein O-GlcNAcylation, a dynamic and reversible glucose-dependent post-translational modification of serine and threonine residues on target proteins, has been proposed to promote vascular smooth muscle cell proliferation and migration events impli... Read More about Do T2DM and Hyperglycaemia Affect the Expression Levels of the Regulating Enzymes of Cellular O-GlcNAcylation in Human Saphenous Vein Smooth Muscle Cells?.