All Projects (115)

BETTER-B: BETter TreatmEnts for Refractory Breathlessness Jan 1, 2019 - Dec 31, 2023

Improving outcomes in patient with diabetic foot disease Jun 1, 2018 - May 31, 2019
Diabetes is the fastest growing health crisis of our time. One person with diabetes dies every 6 seconds. In the UK a new person is diagnosed every 2 minutes and care of diabetes currently costs the NHS £1million per hour, every hour. Diabetes is not... Read More about Improving outcomes in patient with diabetic foot disease.

Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme Apr 1, 2019 - Sep 30, 2021
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive age group females and it is associated with various clinical features including irregular periods, male-pattern hair loss from the head and excess hair in other b... Read More about Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme.

Two-part, double-blind, placebo-controlled, randomized, parallel-group study - (Part 1) in healthy male volunteers to assess safety and tolerability of ascending repeated oral doses of BAY 1817080 followed (Part 2), two-way crossover administration with four-step dose titration in patients with refractory chronic cough to assess safety, tolerability and efficacy for proof of concept and dose-finding Jul 18, 2018 - Dec 31, 2019

A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis Mar 1, 2019 - Sep 30, 2020
Patients with sarcoidosis need treatment options that improve their disease without causing unacceptable side effects. Currently, steroids tablets are offered for severe sarcoidosis, but side effects can be dangerous and personally distressing, and s... Read More about A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis.

Online home-based exercise programme for prevention and treatment of Type 2 Diabetes Jun 11, 2019 - Sep 11, 2019

BICS: A randomised, double-blind placebo controlled trial of the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease Jun 1, 2017 - May 31, 2022

RELIEF: A Randomised, Double-blind, Placebo-Controlled, Crossover, Dose Escalation Study of BLU-5937 in subjects with Unexplained or Refractory Chronic Cough Jun 1, 2020 - Dec 31, 2020

ISABELA1: A Phase 3, randomized, double-blind, parallel-group, placebocontrolled multicenter study to evaluate the efficacy and safety of two doses of GLPG1690 in addition to local standard of care for minimum 52 weeks in subjects with idiopathic pulmonary fibrosis. Aug 1, 2019 - Dec 31, 2022

SCENIC: Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Efficacy and Safety Study with Inhaled RVT-1601 for the Treatment of Persistent Cough in Patients with Idiopathic Pulmonary Fibrosis (IPF) May 1, 2019 - Jan 31, 2022

ATLAS: A Randomized Open-Label, Phase 1b Study of the Safety of Pirfenidone Solution for Inhalation (AP01) in Patients with Idiopathic Pulmonary Fibrosis Jun 1, 2019 - Jan 31, 2022

TR12: A Phase 2, Double-blind, Randomized, Placebo-controlled, Two-Treatment, Two-Period Crossover Efficacy and Safety Study in Idiopathic Pulmonary Fibrosis with Nalbuphine ER Tablets for the Treatment of Cough Oct 1, 2019 - Dec 31, 2022

An exploratory sub-study to protocol GLPG1690-CL-303 to assess lung function in patients with idiopathic pulmonary fibrosis, using hyperpolarized xenon magnetic resonance imaging Nov 1, 2019 - Apr 30, 2022

TRANSFORM: YCR Cancercare: Experiences of diagnostic pathways and cancer care during the COVID-19 pandemic Apr 1, 2021 - Oct 31, 2024
The global coronavirus (COVID-19) outbreak has led to the disruption of cancer care services, as healthcare resources (personnel, facilities) were reprioritised to respond to the pandemic. The implications of this for cancer outcomes and patients’ ps... Read More about TRANSFORM: YCR Cancercare: Experiences of diagnostic pathways and cancer care during the COVID-19 pandemic.

Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: an intervention development study Apr 1, 2022 - Apr 30, 2024
The number of people living with and beyond cancer is growing; many are over 65 years old who often have different and more complicated healthcare needs than younger people.

Being active is one of the best things people with, or who have had, canc... Read More about Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: an intervention development study.

Development and publication of the booklet for the pulmonary fibrosis (disease with a degree of similarity to coronavirus disease). Nov 1, 2020 - Oct 31, 2021
Chronic diseases associated with fibrosis present a challenge for healthcare; two of them are idiopathic pulmonary fibrosis (IPF) and lymphoedema. IPF is a form of lung disease in which scarring occurs (with no known cause) leading to increased breat... Read More about Development and publication of the booklet for the pulmonary fibrosis (disease with a degree of similarity to coronavirus disease)..

TRANSFORM: Improving shared decision-making in malignant bowel obstruction: An exploration of context-specific treatment pathways and experiences to inform intervention development for person-centred care Sep 1, 2021 - Jan 31, 2025

A phase II, randomised feasibility trial of a tailored, home-based exercise programme on disease-free survival among early stage high-risk recurring cancers in Yorkshire Sep 1, 2022 - Aug 31, 2026
To determine the effect exercise has on preventing secondary cancers and improving 5-year survival rates among people diagnosed with breast, bowel, lung, or prostate cancers in Yorkshire.

Randomised, double-blind, parallel group. Phase 2b dose-finding, efficacy and safety study of 12-week twice daily oral administration of BAY 1817080 compared to placebo in the treatment of refractory and/or unexplained chronic cough (RUCC) Jan 1, 2021 - Feb 28, 2022

Consumables for PhD project Study of Tumour Regulatory Molecules as Markers of Malignancy in Pancreatic Cystic Lesions (TEM-PAC) Feb 1, 2021 - Jul 31, 2026