Outputs (568)

VDR gene methylation as a molecular adaption to light exposure: Historic, recent and genetic influences (2017)
Journal Article
Beckett, E., Jones, P., Veysey, M., Duesing, K., Martin, C., Furst, J., Yates, Z., Jablonski, N., Chaplin, G., & Lucock, M. (2017). VDR gene methylation as a molecular adaption to light exposure: Historic, recent and genetic influences. American Journal of Human Biology, 29(5), Article e23010. https://doi.org/10.1002/ajhb.23010

Objectives
The vitamin D receptor (VDR) is a member of the nuclear receptor family of transcription factors. We examined whether degree of VDR gene methylation acts as a molecular adaptation to light exposure. We explored this in the context of phot... Read More about VDR gene methylation as a molecular adaption to light exposure: Historic, recent and genetic influences.

Quality of life in patients with intermittent claudication (2017)
Journal Article
Harwood, A. E., Totty, J. P., Broadbent, E., Smith, G. E., & Chetter, I. C. (2017). Quality of life in patients with intermittent claudication. Gefässchirurgie, 22(3), 159-164. https://doi.org/10.1007/s00772-017-0269-4

© 2017, The Author(s). Background: Intermittent claudication (IC) is a common condition that causes pain in the lower limbs when walking and has been shown to severely impact the quality of life (QoL) of patients. The QoL is therefore often regarded... Read More about Quality of life in patients with intermittent claudication.

Reduced plasma homocysteine levels in elderly Australians following mandatory folic acid fortification – A comparison of two cross-sectional cohorts (2017)
Journal Article
Beckett, E., Martin, C., Boyd, L., Porter, T., King, K., Niblett, S., Yates, Z., Veysey, M., & Lucock, M. (2017). Reduced plasma homocysteine levels in elderly Australians following mandatory folic acid fortification – A comparison of two cross-sectional cohorts. Journal of Nutrition and Intermediary Metabolism, 8, 14-20. https://doi.org/10.1016/j.jnim.2017.04.001

© 2017 Objective In 2009, Australia implemented mandatory folic acid fortification in wheat flour for bread-making. The primary aim was to improve folate status in reproductive-aged women to reduce neural tube defect incidence. However, folic acid co... Read More about Reduced plasma homocysteine levels in elderly Australians following mandatory folic acid fortification – A comparison of two cross-sectional cohorts.

Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study (2017)
Journal Article
Sathyapalan, T., Javed, Z., Rigby, A. S., Kilpatrick, E. S., & Atkin, S. L. (2017). Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study. Journal of the Endocrine Society, 1(5), 423-430. https://doi.org/10.1210/js.2016-1068

© 2017 Endocrine Society. Background: Soy protein with isoflavones appears to have an adverse effect on thyroid function, but it is not known whether it is the protein or isoflavone component that is deleterious. The effect of isoflavone-free soy on... Read More about Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study.

Attitudes of newly qualified doctors towards a career in general practice: A qualitative focus group study (2017)
Journal Article
Merrett, A., Jones, D., Sein, K., Green, T., & Macleod, U. (2017). Attitudes of newly qualified doctors towards a career in general practice: A qualitative focus group study. The British journal of general practice : the journal of the Royal College of General Practitioners, 67(657), e253-e259. https://doi.org/10.3399/bjgp17X690221

© British Journal of General Practice 2017. Background A key element of the NHS is universal access to a GP. Recently, UK general practice has been described as being in crisis, with training places unfilled and multiple practices reporting vacancies... Read More about Attitudes of newly qualified doctors towards a career in general practice: A qualitative focus group study.

Pseudotumor cerebri syndrome in childhood : incidence, clinical profile and risk factors in a national prospective population-based cohort study (2017)
Journal Article
Matthews, Y.-Y., Dean, F., Lim, M. J., Mclachlan, K., Rigby, A. S., Solanki, G. A., White, C. P., Whitehouse, W. P., & Kennedy, C. R. (2017). Pseudotumor cerebri syndrome in childhood : incidence, clinical profile and risk factors in a national prospective population-based cohort study. Archives of Disease in Childhood, 102(8), 715-721. https://doi.org/10.1136/archdischild-2016-312238

Aim To investigate the epidemiology, clinical profile and risk factors of pseudotumor cerebri syndrome (PTCS) in children aged 1-16 years. Methods A national prospective population-based cohort study over 25 months. Newly diagnosed PTCS cases notifie... Read More about Pseudotumor cerebri syndrome in childhood : incidence, clinical profile and risk factors in a national prospective population-based cohort study.

Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation (2017)
Journal Article
Crooks, M. G., den Brinker, A., Hayman, Y., Williamson, J. D., Innes, A., Wright, C. E., Hill, P., & Morice, A. H. (2017). Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation. Lung, 195(3), 289-294. https://doi.org/10.1007/s00408-017-9996-2

Purpose Cough is common in chronic obstructive pulmonary disease (COPD) and is associated with frequent exacerbations and increased mortality. Cough increases during acute exacerbations (AE-COPD), representing a possible metric of clinical deteriorat... Read More about Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation.

The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration? (2017)
Journal Article
Hayman, Y. A., Sadofsky, L. R., Williamson, J. D., Hart, S. P., & Morice, A. H. (2017). The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration?. Ers Monograph, 3(1), 00026-2016. https://doi.org/10.1183/23120541.00026-2016

Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid laden macrophages (LLM) within the airway may indicate aspiration secondary to GOR. The proposed mechanis... Read More about The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration?.

Exploring the performance reserve: Effect of different magnitudes of power output deception on 4,000 m cycling time-trial performance (2017)
Journal Article
Stone, M. R., Thomas, K., Wilkinson, M., Stevenson, E., St. Clair Gibson, A., Jones, A. M., & Thompson, K. G. (in press). Exploring the performance reserve: Effect of different magnitudes of power output deception on 4,000 m cycling time-trial performance. PLoS ONE, 12(3), Article e0173120. https://doi.org/10.1371/journal.pone.0173120

Purpose The aim of the present study was to investigate whether a magnitude of deception of 5% in power output would lead to a greater reduction in the amount of time taken for participants to complete a 4000 m cycling TT than a magnitude of deceptio... Read More about Exploring the performance reserve: Effect of different magnitudes of power output deception on 4,000 m cycling time-trial performance.

Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial) (2017)
Journal Article
Harwood, A. E., Smith, G. E., Totty, J. P., Carradice, D., Chetter, I. C., Harwood, A., Totty, J., Cayton, T., & Smith, G. (2017). Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial). Trials, 18(1), https://doi.org/10.1186/s13063-017-1844-4

© 2017 The Author(s). Background: Peripheral arterial disease (PAD) has a population prevalence of 4.6% with intermittent claudication (IC) presenting as one of the earliest and most common symptoms. PAD has detrimental effects on patients' walking a... Read More about Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial).