Outputs (37)

Effects of exercise dose and type during breast cancer chemotherapy: Multicenter randomized trial (2013)
Journal Article
Courneya, K. S., McKenzie, D. C., Mackey, J. R., Gelmon, K., Friedenreich, C. M., Yasui, Y., Reid, R. D., Cook, D., Jespersen, D., Proulx, C., Dolan, L. B., Forbes, C. C., Wooding, E., Trinh, L., & Segal, R. J. (2013). Effects of exercise dose and type during breast cancer chemotherapy: Multicenter randomized trial. JNCI: Journal of the National Cancer Institute, 105(23), 1821-1832. https://doi.org/10.1093/jnci/djt297

Background
Exercise improves physical functioning and symptom management during breast cancer chemotherapy, but the effects of different doses and types of exercise are unknown.

Methods
A multicenter trial in Canada randomized 301 breast cancer pati... Read More about Effects of exercise dose and type during breast cancer chemotherapy: Multicenter randomized trial.

Workshop - Developing Clinical Reasoning Skills in Modern Undergraduate Medical Curricula (2013)
Presentation / Conference Contribution
Hammond, A., & Henderson, J. (2013, September). Workshop - Developing Clinical Reasoning Skills in Modern Undergraduate Medical Curricula. Presented at 8th HYMS Education Conference, Bishop Burton, East Yorkshire

Objectives:
Following the workshop participants will be able to
* Recognise opportunities to strengthen the teaching of clinical reasoning within their environment
* Evaluate students’ individual clinical reasoning learning needs
* Discuss curre... Read More about Workshop - Developing Clinical Reasoning Skills in Modern Undergraduate Medical Curricula.

Using SABRE in NMR and MRI (2013)
Thesis
Highton, L. A. R. Using SABRE in NMR and MRI. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4215427

This thesis describes the use of SABRE as a hyperpolarisation technique in both NMR spectroscopy and MRI. Hyperpolarisation is a method of generating enhanced magnetic resonance signals to improve signal to noise, contrast and resolution within those... Read More about Using SABRE in NMR and MRI.

Proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia reveals a possible role for kininogen (2013)
Journal Article
Kashuba, E., Eagle, G. L., Bailey, J., Evans, P., Welham, K. J., Allsup, D., & Cawkwell, L. (2013). Proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia reveals a possible role for kininogen. Journal of Proteomics, 91, 478-485. https://doi.org/10.1016/j.jprot.2013.08.002

CLL is an incurable disease with variable prognosis. The hyper reactivity of the B-cell receptor (BCR) to unknown antigen ligation plays a pivotal role in CLL-cell survival. We aimed to investigate the BCR signalling pathway using proteomics to ident... Read More about Proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia reveals a possible role for kininogen.

Patient satisfaction with participation in a randomized exercise trial: Effects of randomization and a usual care posttrial exercise program (2013)
Journal Article
Courneya, K. S., Forbes, C. C., Trinh, L., Sellar, C. M., Friedenreich, C. M., & Reiman, T. (2013). Patient satisfaction with participation in a randomized exercise trial: Effects of randomization and a usual care posttrial exercise program. Clinical Trials, 10(6), 959-966. https://doi.org/10.1177/1740774513495985

Background
Participation in an exercise trial is a major commitment for cancer survivors, but few exercise trials have evaluated patient satisfaction with trial participation.

Purpose
To examine patient satisfaction with participation in the Healthy... Read More about Patient satisfaction with participation in a randomized exercise trial: Effects of randomization and a usual care posttrial exercise program.

Workshop: Helping undergraduate medical students to improve their clinical reasoning in the direct patient encounter - skills for tutors (2013)
Presentation / Conference Contribution
Hammond, A., & Henderson, J. (2013, July). Workshop: Helping undergraduate medical students to improve their clinical reasoning in the direct patient encounter - skills for tutors. Presented at Association for the Study of Medical Education Annual Scientific Meeting: Changes in healthcare delivery and the effects on medical education, Edinburgh

Workshop Description:
This workshop demonstrates how clinical consultations can be used in a structured way to facilitate student understanding of their own clinical reasoning. Participants will actively explore, analyse and practise some of the sk... Read More about Workshop: Helping undergraduate medical students to improve their clinical reasoning in the direct patient encounter - skills for tutors.

Increased frequency and suppressive activity of CD127low/- regulatory T cells in the peripheral circulation of patients with head and neck squamous cell carcinoma are associated with advanced stage and nodal involvement (2013)
Journal Article
Drennan, S., Stafford, N. D., Greenman, J., & Green, V. (2013). Increased frequency and suppressive activity of CD127low/- regulatory T cells in the peripheral circulation of patients with head and neck squamous cell carcinoma are associated with advanced stage and nodal involvement. Immunology, 140(3), 335-343. https://doi.org/10.1111/imm.12144

The presence of regulatory T (Treg) cells is thought to be an important mechanism by which head and neck squamous cell carcinoma (HNSCC) successfully evades the immune system. Using multicolour flow cytometry, the frequency and functional capacity of... Read More about Increased frequency and suppressive activity of CD127low/- regulatory T cells in the peripheral circulation of patients with head and neck squamous cell carcinoma are associated with advanced stage and nodal involvement.

Involvement of TRPC Channels in Lung Cancer Cell Differentiation and the Correlation Analysis in Human Non-Small Cell Lung Cancer (2013)
Journal Article
Jiang, H. N., Zeng, B., Zhang, Y., Daskoulidou, N., Fan, H., Qu, J. M., & Xu, S. Z. (2013). Involvement of TRPC Channels in Lung Cancer Cell Differentiation and the Correlation Analysis in Human Non-Small Cell Lung Cancer. PLoS ONE, 8(6), Article e67637. https://doi.org/10.1371/journal.pone.0067637

The canonical transient receptor potential (TRPC) channels are Ca2+-permeable cationic channels controlling the Ca2+ influx evoked by G protein-coupled receptor activation and/or by Ca2+ store depletion. Here we investigate the involvement of TRPCs i... Read More about Involvement of TRPC Channels in Lung Cancer Cell Differentiation and the Correlation Analysis in Human Non-Small Cell Lung Cancer.

Glycemic Control in the 12 Months following a Change to SI Hemoglobin A1c Reporting Units (2013)
Journal Article
Rigby, A., Atkin, S., Barth, J. H., & Kilpatrick, E. (2013). Glycemic Control in the 12 Months following a Change to SI Hemoglobin A1c Reporting Units. Clinical Chemistry, 59(10), 1457-1460. https://doi.org/10.1373/clinchem.2013.206334

BACKGROUND Many countries have implemented, or are considering, a change in hemoglobin A1c (Hb A1c) units from traditional percentage values [Diabetes Control and Complications Trial (DCCT)] to the new Système International d'Unités (SI) unit in mill... Read More about Glycemic Control in the 12 Months following a Change to SI Hemoglobin A1c Reporting Units.

Extension MRI is clinically useful in cervical myelopathy (2013)
Journal Article
Bartlett, R. J. V., Rigby, A. S., Joseph, J., Raman, A., Kunnacherry, A., & Hill, C. A. R. (2013). Extension MRI is clinically useful in cervical myelopathy. Neuroradiology, 55(9), 1081-1088. https://doi.org/10.1007/s00234-013-1208-z

Introduction: Cervical spine MRI with the neck in extension has been well described over the last 10 years, but its clinical value remains unknown. Methods: We performed extension imaging in 60 patients in whom the initial neutral study showed border... Read More about Extension MRI is clinically useful in cervical myelopathy.