Outputs (56)

Hospital admissions in the last year of life of patients with heart failure (2024)
Journal Article
AI Abel, A., Samuel, N. A., Cuthbert, J. J., Brown, O. I., Pellicori, P., Kazmi, S., GF Cleland, J., Johnson, M., & Clark, A. L. (2024). Hospital admissions in the last year of life of patients with heart failure. European Heart Journal - Quality of Care and Clinical Outcomes, 10(2), 168-175. https://doi.org/10.1093/ehjqcco/qcad047

Aim To explore the frequency, causes, and pattern of hospitalisation for patients with chronic heart failure (HF) in the 12 months preceding death. We also investigated cause of death. Methods Patients referred to a secondary care HF clinic were rout... Read More about Hospital admissions in the last year of life of patients with heart failure.

Student's perspectives of inclusive practices in anatomy education (2024)
Journal Article
Longhurst, G. J., Bazira, P. J., & Finn, G. M. (2024). Student's perspectives of inclusive practices in anatomy education. Anatomical Sciences Education, 17(3), 571-590. https://doi.org/10.1002/ase.2388

There is a drive to implement inclusive practices in anatomy by adapting curricula and utilizing inclusive language and resources that negate biases. However, to date there is no data regarding student's perception of inclusivity. Therefore, the stud... Read More about Student's perspectives of inclusive practices in anatomy education.

Roles of TRIM24 in macrophage activation and experimental visceral leishmaniasis (2024)
Thesis
Muscutt, E. W. Roles of TRIM24 in macrophage activation and experimental visceral leishmaniasis. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4557553

Visceral leishmaniasis (VL) causes immune and haematological dysfunction and is fatal in >95% of cases if left untreated. While macrophages are vital for efficient Leishmania parasite clearance, parasite-macrophage interactions are critical for VL pr... Read More about Roles of TRIM24 in macrophage activation and experimental visceral leishmaniasis.

Tailored risk assessment and forecasting in intermittent claudication (2024)
Journal Article
Ravindhran, B., Prosser, J., Lim, A., Lathan, R., Mishra, B., Hitchman, L., Smith, G. E., Carradice, D., Thakker, D., Chetter, I. C., & Pymer, S. (2024). Tailored risk assessment and forecasting in intermittent claudication. BJS Open, 8(1), Article zrad166. https://doi.org/10.1093/bjsopen/zrad166

Background: Guidelines recommend cardiovascular risk reduction and supervised exercise therapy as the first line of treatment in intermittent claudication, but implementation challenges and poor patient compliance lead to significant variation in man... Read More about Tailored risk assessment and forecasting in intermittent claudication.

A feasibility survey to inform trial design investigating surgical site infection prevention in vascular surgery (2024)
Journal Article
Lathan, R., Hitchman, L., Long, J., Gwilym, B., Wall, M., Juszczak, M., Smith, G., Popplewell, M., Bosanquet, D., Hinchliffe, R., Pinkney, T., & Chetter, I. (2024). A feasibility survey to inform trial design investigating surgical site infection prevention in vascular surgery. Journal of Vascular Societies Great Britain and Ireland, 3(2), 76-83. https://doi.org/10.54522/jvsgbi.2024.116

Introduction: Current surgical site infection (SSI) prevention guidance indicates low-quality evidence supporting many of their recommendations. Subsequently, there is substantial variation in practice and often implementation of unsubstantiated inte... Read More about A feasibility survey to inform trial design investigating surgical site infection prevention in vascular surgery.

Digital health interventions for all? Examining inclusivity across all stages of the digital health intervention research process (2024)
Journal Article
Krukowski, R. A., Ross, K. M., Western, M. J., Cooper, R., Busse, H., Forbes, C., Kuntsche, E., Allmeta, A., Silva, A. M., John-Akinola, Y. O., & König, L. M. (2024). Digital health interventions for all? Examining inclusivity across all stages of the digital health intervention research process. Trials, 25(1), Article 98. https://doi.org/10.1186/s13063-024-07937-w

Digital interventions offer many possibilities for improving health, as remote interventions can enhance reach and access to underserved groups of society. However, research evaluating digital health interventions demonstrates that such technologies... Read More about Digital health interventions for all? Examining inclusivity across all stages of the digital health intervention research process.

Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making (2024)
Journal Article
Bravington, A., Boland, J. W., Greenley, S., Lind, M., Murtagh, F. E., Patterson, M., Pearson, M., & Johnson, M. J. (2024). Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making. PLoS ONE, 19(1 January), Article e0294218. https://doi.org/10.1371/journal.pone.0294218

Introduction Malignant bowel obstruction is a distressing complication of cancer, causing pain, nausea and vomiting, and often has a poor prognosis. Severe and rapidly developing symptoms, a lack of robust clinical guidelines and the need for multidi... Read More about Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making.

Experiences of a student with a visual impairment transitioning to higher education: A narrative inquiry (2024)
Journal Article
Tomlinson, A., & Killingback, C. (2024). Experiences of a student with a visual impairment transitioning to higher education: A narrative inquiry. British Journal of Visual Impairment, https://doi.org/10.1177/02646196231225071

Transition to higher education is a considerable period of change for students, and can be a particularly challenging time for students with a visual impairment. The aim of this study was to understand the transition experiences of an undergraduate s... Read More about Experiences of a student with a visual impairment transitioning to higher education: A narrative inquiry.

Standard Versus Modified Ipilimumab, in Combination With Nivolumab, in Advanced Renal Cell Carcinoma: A Randomized Phase II Trial (PRISM) (2024)
Journal Article
Vasudev, N. S., Ainsworth, G., Brown, S., Pickering, L., Waddell, T., Fife, K., Griffiths, R., Sharma, A., Katona, E., Howard, H., Velikova, G., Maraveyas, A., Brown, J., Pezaro, C., Tuthill, M., Boleti, E., Bahl, A., Szabados, B., Banks, R. E., Brown, J., …Powles, T. (2024). Standard Versus Modified Ipilimumab, in Combination With Nivolumab, in Advanced Renal Cell Carcinoma: A Randomized Phase II Trial (PRISM). Journal of Clinical Oncology, 42(3), 312-323. https://doi.org/10.1200/JCO.23.00236

PURPOSE: Ipilimumab (IPI), in combination with nivolumab (NIVO), is an approved frontline treatment option for patients with intermediate- or poor-risk advanced renal cell carcinoma (aRCC). We conducted a randomized phase II trial to evaluate whether... Read More about Standard Versus Modified Ipilimumab, in Combination With Nivolumab, in Advanced Renal Cell Carcinoma: A Randomized Phase II Trial (PRISM).

Diuretic Treatment in Patients with Heart Failure: Current Evidence and Future Directions – Part I: Loop Diuretics (2024)
Journal Article
Cuthbert, J. J., & Clark, A. L. (2024). Diuretic Treatment in Patients with Heart Failure: Current Evidence and Future Directions – Part I: Loop Diuretics. Current Heart Failure Reports, 21(2), 101-114. https://doi.org/10.1007/s11897-024-00643-3

Purpose of Review: Fluid retention or congestion is a major cause of symptoms, poor quality of life, and adverse outcome in patients with heart failure (HF). Despite advances in disease-modifying therapy, the mainstay of treatment for congestion—loop... Read More about Diuretic Treatment in Patients with Heart Failure: Current Evidence and Future Directions – Part I: Loop Diuretics.