Outputs (68)

The impact of project portfolio management practices on the relationship between organizational ambidexterity and project performance success (2021)
Journal Article
Ojiako, U., Petro, Y., Marshall, A., & Williams, T. (in press). The impact of project portfolio management practices on the relationship between organizational ambidexterity and project performance success. Production planning & control, https://doi.org/10.1080/09537287.2021.1909168

Some studies suggest that organizational ambidexterity is best orchestrated through individual projects. However, stand-alone individual projects are relatively limited in scope, while suffering from susceptibilities to horizontal and vertical segmen... Read More about The impact of project portfolio management practices on the relationship between organizational ambidexterity and project performance success.

Progression to Dementia in Mild Cognitive Impairment with Lewy Bodies or Alzheimer Disease (2021)
Journal Article
Hamilton, C. A., Matthews, F. E., Donaghy, P. C., Taylor, J. P., O'Brien, J. T., Barnett, N., Olsen, K., Durcan, R., Roberts, G., Ciafone, J., Barker, S. A., Firbank, M., McKeith, I. G., & Thomas, A. J. (2021). Progression to Dementia in Mild Cognitive Impairment with Lewy Bodies or Alzheimer Disease. Neurology, 96(22), E2685-E2693. https://doi.org/10.1212/WNL.0000000000012024

ObjectiveTo determine whether mild cognitive impairment with Lewy bodies or mild cognitive impairment with Alzheimer disease differ in their rates of clinical progression to dementia, we undertook longitudinal observation of mild cognitive impairment... Read More about Progression to Dementia in Mild Cognitive Impairment with Lewy Bodies or Alzheimer Disease.

Trends in life expectancy and healthy life years at birth and age 65 in the UK, 2008–2016, and other countries of the EU28: An observational cross-sectional study (2021)
Journal Article
Welsh, C. E., Matthews, F. E., & Jagger, C. (2021). Trends in life expectancy and healthy life years at birth and age 65 in the UK, 2008–2016, and other countries of the EU28: An observational cross-sectional study. The Lancet Regional Health Europe, 2, Article 100023. https://doi.org/10.1016/j.lanepe.2020.100023

Background: As society ages, promoting the health of the extra years of life is of paramount importance for health, social care and pension provision. Increases in life expectancy in the UK and elsewhere have slowed in recent years, but the reasons f... Read More about Trends in life expectancy and healthy life years at birth and age 65 in the UK, 2008–2016, and other countries of the EU28: An observational cross-sectional study.

Prevalence and factors associated with poor performance in the 5-chair stand test: findings from the Cognitive Function and Ageing Study II and proposed Newcastle protocol for use in the assessment of sarcopenia (2021)
Journal Article
Dodds, R. M., Murray, J. C., Granic, A., Hurst, C., Uwimpuhwe, G., Richardson, S., Brayne, C., Matthews, F. E., Sayer, A. A., Arthur, A., Baldwin, C., Barnes, L. E., Comas-Herrera, A., Dening, T., Forster, G., Harrison, S., Ince, P. G., Jagger, C., McKeith, I. G., Parry, B., …Woods, B. (2021). Prevalence and factors associated with poor performance in the 5-chair stand test: findings from the Cognitive Function and Ageing Study II and proposed Newcastle protocol for use in the assessment of sarcopenia. Journal of Cachexia, Sarcopenia and Muscle, 12(2), 308-318. https://doi.org/10.1002/jcsm.12660

Background: Poor performance in the 5-chair stand test (5-CST) indicates reduced lower limb muscle strength. The 5-CST has been recommended for use in the initial assessment of sarcopenia, the accelerated loss of muscle strength and mass. In order to... Read More about Prevalence and factors associated with poor performance in the 5-chair stand test: findings from the Cognitive Function and Ageing Study II and proposed Newcastle protocol for use in the assessment of sarcopenia.

Dementia in the older population is associated with neocortex content of serum amyloid P component (2021)
Journal Article
Ellmerich, S., Taylor, G. W., Richardson, C. D., Minett, T., Schmidt, A. F., Brayne, C., Matthews, F. E., Ince, P. G., Wharton, S. B., & Pepys, M. B. (2021). Dementia in the older population is associated with neocortex content of serum amyloid P component. Brain Communications, 3(4), Article fcab225. https://doi.org/10.1093/braincomms/fcab225

Despite many reported associations, the direct cause of neurodegeneration responsible for cognitive loss in Alzheimer's disease and some other common dementias is not known. The normal human plasma protein, serum amyloid P component, a constituent of... Read More about Dementia in the older population is associated with neocortex content of serum amyloid P component.

Current and future prevalence estimates of mild cognitive impairment, dementia, and its subtypes in a population-based sample of people 70 years and older in Norway: The HUNT study (2021)
Journal Article
Gjøra, L., Strand, B. H., Bergh, S., Borza, T., Brækhus, A., Engedal, K., Johannessen, A., Kvello-Alme, M., Krokstad, S., Livingston, G., Matthews, F. E., Myrstad, C., Skjellegrind, H., Thingstad, P., Aakhus, E., Aam, S., & Selbæk, G. (2021). Current and future prevalence estimates of mild cognitive impairment, dementia, and its subtypes in a population-based sample of people 70 years and older in Norway: The HUNT study. Journal of Alzheimer's Disease, 79(3), 1213-1226. https://doi.org/10.3233/JAD-201275

Background: Having accurate, up-to-date information on the epidemiology of mild cognitive impairment (MCI) and dementia is imperative. Objective: To determine the prevalence of MCI and dementia in Norway using data from a large population-based study... Read More about Current and future prevalence estimates of mild cognitive impairment, dementia, and its subtypes in a population-based sample of people 70 years and older in Norway: The HUNT study.

Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer’s and small vessel disease pathologies (2020)
Journal Article
Waller, R., Narramore, R., Simpson, J. E., Heath, P. R., Verma, N., Tinsley, M., Barnes, J. R., Haris, H. T., Henderson, F. E., Matthews, F. E., Richardson, C. D., Brayne, C., Ince, P. G., Kalaria, R. N., & Wharton, S. B. (2021). Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer’s and small vessel disease pathologies. Brain Pathology, 31(3), Article e12928. https://doi.org/10.1111/bpa.12928

White matter lesions (WML) are common in the ageing brain, often arising in a field effect of diffuse white matter abnormality. Although WML are associated with cerebral small vessel disease (SVD) and Alzheimer’s disease (AD), their cause and pathoge... Read More about Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer’s and small vessel disease pathologies.

Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study (2020)
Journal Article
Röhr, S., Pabst, A., Riedel-Heller, S. G., Jessen, F., Turana, Y., Handajani, Y. S., Brayne, C., Matthews, F. E., Stephan, B. C., Lipton, R. B., Katz, M. J., Wang, C., Guerchet, M., Preux, P. M., Mbelesso, P., Ritchie, K., Ancelin, M. L., Carrière, I., Guaita, A., Davin, A., …Sachdev, P. S. (2020). Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study. Alzheimer's Research and Therapy, 12(1), Article 167. https://doi.org/10.1186/s13195-020-00734-y

Background: Subjective cognitive decline (SCD) is recognized as a risk stage for Alzheimer’s disease (AD) and other dementias, but its prevalence is not well known. We aimed to use uniform criteria to better estimate SCD prevalence across internation... Read More about Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study.

Timing of GP end-of-life recognition in people aged ≥75 years: Retrospective cohort study using data from primary healthcare records in England (2020)
Journal Article
Stow, D., Matthews, F. E., & Hanratty, B. (2020). Timing of GP end-of-life recognition in people aged ≥75 years: Retrospective cohort study using data from primary healthcare records in England. The British journal of general practice : the journal of the Royal College of General Practitioners, 70(701), E874-E879. https://doi.org/10.3399/bjgp20X713417

Background High-quality, personalised palliative care should be available to all, but timely recognition of end of life may be a barrier to end-of-life care for older people. Aim To investigate the timing of end-of-life recognition, palliative regist... Read More about Timing of GP end-of-life recognition in people aged ≥75 years: Retrospective cohort study using data from primary healthcare records in England.

Changes in health and functioning of care home residents over two decades: what can we learn from population-based studies? (2020)
Journal Article
Barker, R. O., Hanratty, B., Kingston, A., Ramsay, S. E., & Matthews, F. E. (2021). Changes in health and functioning of care home residents over two decades: what can we learn from population-based studies?. Age and ageing, 50(3), 921-927. https://doi.org/10.1093/ageing/afaa227

Background: Care home residents have complex care and support needs. There is a perception that the needs of residents have increased, but the evidence is limited. We investigated changes in health and functioning of care home residents over two deca... Read More about Changes in health and functioning of care home residents over two decades: what can we learn from population-based studies?.