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Outputs (460)

Exploring UK clinician perceptions of through-knee amputation compared to above-knee amputation: a mixed methods study (2024)
Journal Article
Gordon, H., Boam, G., Carradice, D., Smith, G. E., & Twiddy, M. (online). Exploring UK clinician perceptions of through-knee amputation compared to above-knee amputation: a mixed methods study. Disability and Rehabilitation, https://doi.org/10.1080/09638288.2024.2441423

Background: Through-knee amputation (TKA) has potential advantages over above-knee amputation (AKA) but is rarely performed in the United Kingdom (UK). This mixed methods study aimed to explore clinicians’ perceptions of TKA compared to AKA. Method:... Read More about Exploring UK clinician perceptions of through-knee amputation compared to above-knee amputation: a mixed methods study.

The relationship between muscle mass changes and protein or energy intake in critically ill children: A systematic review and meta-analysis (2024)
Journal Article
Stacey, L. J., Valla, F. V., Huang, C., Comfort, P., Chaparro, C. J., Latten, L., & Tume, L. N. (in press). The relationship between muscle mass changes and protein or energy intake in critically ill children: A systematic review and meta-analysis. Journal of Parenteral and Enteral Nutrition, https://doi.org/10.1002/jpen.2715

Survivorship after pediatric critical illness is high in developed countries, but many suffer physical morbidities afterwards. The increasing focus on follow-up after critical illness has led to more pediatric studies reporting muscle mass changes (u... Read More about The relationship between muscle mass changes and protein or energy intake in critically ill children: A systematic review and meta-analysis.

Exploring COPD patients’ and carers’ experiences, understandings and expectations of exacerbations: an interview study (2024)
Journal Article
Hutchinson, A., Russell, R., Cummings, H., Usmani, O., MacFadyen, S., Cohen, J., Morris, T., Muellerova, H., Xu, Y., Hellens, G., Roy, K., & Crooks, M. G. (2025). Exploring COPD patients’ and carers’ experiences, understandings and expectations of exacerbations: an interview study. BJGP Open, https://doi.org/10.3399/BJGPO.2024.0026

Background: Chronic Obstructive Pulmonary Disease (COPD) exacerbations are clinically significant events that affect millions globally.
Aim: To explore patients’ and carers’ experiences, understandings and responses to exacerbations.
Design and... Read More about Exploring COPD patients’ and carers’ experiences, understandings and expectations of exacerbations: an interview study.

Tailored Risk Assessment and Forecasting in Intermittent Claudication: A Proof of Concept Decision Support Tool (2024)
Presentation / Conference Contribution
Ravindhran, B., Prosser, J., Lim, A., Mishra, B., Lathan, R., Hitchman, L., Smith, G., Carradice, D., Thakker, D., Pymer, S., & Chetter, I. (2024, June). Tailored Risk Assessment and Forecasting in Intermittent Claudication: A Proof of Concept Decision Support Tool. Presented at The European Society for Vascular Surgery Translational Spring Meeting 2024, Stockholm, Sweden

Interventions to improve clinical trial recruitment with a focus on clinical staff from the recruiting site: a systematic review (2024)
Journal Article
Hermann, L., Arundel, C., Thomas, A., Twiddy, M., & Clark, L. (in press). Interventions to improve clinical trial recruitment with a focus on clinical staff from the recruiting site: a systematic review. Research Methods in Medicine & Health Sciences, https://doi.org/10.1177/26320843241289094

Abstract
Background
Difficulties recruiting to clinical trials are well-documented. Strategies to engage staff from the clinical site where recruitment takes place may be helpful in increasing recruitment rates.
Aim
To systematically review the l... Read More about Interventions to improve clinical trial recruitment with a focus on clinical staff from the recruiting site: a systematic review.

Breathlessness without borders: a call to action for global breathlessness research (2024)
Journal Article
Clark, J. D., Binnie, K., Bond, M., Crooks, M., Currow, D. C., Curry, J., Elsey, H., Habib, M., Hutchinson, A., Soyiri, I., Johnson, M. J., Nair, S., Rao, S., Siqueira-Filha, N., Spathis, A., & Williams, S. (2024). Breathlessness without borders: a call to action for global breathlessness research. NPJ Primary Care Respiratory Medicine, 34(1), Article 26. https://doi.org/10.1038/s41533-024-00384-9

It is likely that the burden of breathlessness in low and middle-income countries (LMICs) is much higher than has been estimated using calculations of disease burden and expected prevalence of the symptom. However, most breathlessness research has be... Read More about Breathlessness without borders: a call to action for global breathlessness research.

Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B) (2024)
Journal Article
Higginson, I. J., Brown, S. T., Oluyase, A. O., May, P., Maddocks, M., Costantini, M., Bajwah, S., Normand, C., Bausewein, C., Simon, S. T., Ryan, K., Currow, D. C., Johnson, M., Hart, S. P., Mather, H., Krajnik, M., Tanzi, S., Ghirotto, L., Bolton, C., Janowiak, P., …Brown, J. M. (2024). Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B). Lancet, 12(10), 763-774. https://doi.org/10.1016/S2213-2600%2824%2900187-5

Background
Breathlessness frequently becomes severe among people with respiratory disease. Mirtazapine, a widely used antidepressant, showed promise. We determined the effectiveness of mirtazapine to alleviate severe persisting breathlessness.
Meth... Read More about Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B).

Factors Influencing the Implementation of Digital Advance Care Planning: Qualitative Interview Study (2024)
Journal Article
Bradshaw, A., Birtwistle, J., Evans, C. J., Sleeman, K. E., Richards, S., Foy, R., Martin, P. M., Carder, P., Allsop, M. J., & Twiddy, M. (2024). Factors Influencing the Implementation of Digital Advance Care Planning: Qualitative Interview Study. Journal of medical Internet research, 26, Article e50217. https://doi.org/10.2196/50217

BACKGROUND: Palliative care aims to improve the quality of life for people with life-limiting illnesses. Advance care planning conversations that establish a patient's wishes and preferences for care are part of a person-centered approach. Internatio... Read More about Factors Influencing the Implementation of Digital Advance Care Planning: Qualitative Interview Study.