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Projects (25)

PUMA: Paediatric early warning system (PEWS): Utilisation and Mortality Avoidance. A prospective, mixed methods, before and after study identifying the evidence base for the core components of an effective PEWS and the development of an implementation package for implementation and use in the UK Oct 1, 2017 - Oct 31, 2018
In 2011 a research study compared the child health outcomes and death rate in the UK with other European countries. It was worrying that UK measures of child health were amongst the worst in Europe. It is not clear why that is and further work needs... Read More about PUMA: Paediatric early warning system (PEWS): Utilisation and Mortality Avoidance. A prospective, mixed methods, before and after study identifying the evidence base for the core components of an effective PEWS and the development of an implementation package for implementation and use in the UK.

BRAVO: High grade bladder cancer: a randomised controlled trial of radical cystectomy against intra-vesical immunotherapy – a feasibility study Oct 1, 2017 - Sep 30, 2018
Bladder cancer is a common disease with worse outcomes in Yorkshire than in the rest of the UK. We want to conduct a randomized trial to evaluate the best treatment for aggressive bladder cancer when found at an early stage. This could be complete b... Read More about BRAVO: High grade bladder cancer: a randomised controlled trial of radical cystectomy against intra-vesical immunotherapy – a feasibility study.

NIFTy: Near Infrared Fluorescence imaging to prevent post-surgical hypoparathyroidism after thyriod surgery - a phase II/III pragmatic, multi-centre rct Oct 1, 2019 - Jul 31, 2024
Parathyroid glands are tiny glands in the neck behind the thyroid gland that control the level of calcium in the blood. More than 12,000 patients undergo thyroid surgery every year in England alone (HES dataset). A common complication of thyroid surg... Read More about NIFTy: Near Infrared Fluorescence imaging to prevent post-surgical hypoparathyroidism after thyriod surgery - a phase II/III pragmatic, multi-centre rct.

EPaCCS: Electronic Palliative Care Co-ordination Systems (EPaCCS) in end of life care: evaluating their implementation and optimising future service provision. Sep 1, 2020 - Nov 30, 2023
It is not clear how Electronic Palliative Care Co-ordination Systems (EPaCCS) are being implemented across England, what problems healthcare professionals face in using EPaCCS, what views patients and caregivers have on EPaCCS, and how EPaCCS affect... Read More about EPaCCS: Electronic Palliative Care Co-ordination Systems (EPaCCS) in end of life care: evaluating their implementation and optimising future service provision..

PPI for PBP research - Exploring the role, responsibilities and impact of pharmacists working in primary care (GP surgeries) Apr 1, 2019 - Sep 30, 2019
Both local and national initiatives seek to recruit more pharmacists to work in GP practices. Following a successful pilot, NHS England have committed to recruit up to 2000 pharmacists by 2020 to work clinically in general practice settings; this is... Read More about PPI for PBP research - Exploring the role, responsibilities and impact of pharmacists working in primary care (GP surgeries).

Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: an intervention development study Apr 1, 2022 - Apr 30, 2024
The number of people living with and beyond cancer is growing; many are over 65 years old who often have different and more complicated healthcare needs than younger people.

Being active is one of the best things people with, or who ha... Read More about Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: an intervention development study.

The TRANSPIRE Study: A prospective observational study to explore the relationship between nuTRition, protein intake ANd muScle mass loss during and after Pediatric Intensive caRE Aug 1, 2021 - Jul 31, 2023
Around 20 000 children are admitted to PICU each year in the UK and Ireland and around 13,000 of these stay more than 3 days in intensive care, with some children staying a lot longer. As children’s intensive care in the UK has improved in the last d... Read More about The TRANSPIRE Study: A prospective observational study to explore the relationship between nuTRition, protein intake ANd muScle mass loss during and after Pediatric Intensive caRE.

REMEDI4ALL BUILDING A SUSTAINABLE EUROPEAN INNOVATION PLATFORM TO ENHANCE THE REPURPOSING OF MEDICINES FOR ALL Sep 1, 2022 - Aug 31, 2027
Osteogenesis imperfecta (OI) causes skeletal fragility, bone pain, sarcopenia and reduced connective tissue resilience, shown as hypermobility and aortic root dilatation (in adults). There is no effective treatment for OI. Current agents only target... Read More about REMEDI4ALL BUILDING A SUSTAINABLE EUROPEAN INNOVATION PLATFORM TO ENHANCE THE REPURPOSING OF MEDICINES FOR ALL.

Mortality Risk Prediction of ICU Patients with Sepsis Considering Dynamic Time Series Characteristics under Uncertainty Mar 31, 2023 - Mar 30, 2025
ICU patients with sepsis have rapidly changing conditions and high mortality. Because of it, early prediction and timely intervention are the keys to reducing the risk of death.
The project aims to provide critical care physicians with an int... Read More about Mortality Risk Prediction of ICU Patients with Sepsis Considering Dynamic Time Series Characteristics under Uncertainty.