Outputs (375)

Midwifery-led antenatal pelvic floor muscle exercise intervention to reduce postnatal urinary incontinence: APPEAL research programme including a feasibility and pilot cluster RCT (2024)
Journal Article
Macarthur, C., Bick, D., Salmon, V., Jones, E., Hay-Smith, J., Bishop, J., Gkini, E., Hemming, K., Webb, S., Pearson, M., Coleman, T., Terry, R., Edwards, L., Frawley, H., Oborn, E., & Dean, S. (2024). Midwifery-led antenatal pelvic floor muscle exercise intervention to reduce postnatal urinary incontinence: APPEAL research programme including a feasibility and pilot cluster RCT. Programme Grants for Applied Research, 12(9), https://doi.org/10.3310/TJDH7946

Background: Antenatal pelvic floor muscle exercises are effective in reducing postnatal urinary incontinence. Midwives, however, lack training and confidence to promote these exercises and often do not provide information or support to women to do th... Read More about Midwifery-led antenatal pelvic floor muscle exercise intervention to reduce postnatal urinary incontinence: APPEAL research programme including a feasibility and pilot cluster RCT.

Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer (2024)
Journal Article
Martens, E. S., Becker, D., Abele, C., Abbel, D., Achterberg, W. P., Bax, J. J., Bertoletti, L., Edwards, M. E., Font, C., Gava, A., Goedegebuur, J., Højen, A. A., Huisman, M. V., Kruip, M. J., Mahé, I., Mooijaart, S. P., Pearson, M., Seddon, K., Szmit, S., Noble, S. I., …Konstantinides, S. V. (2025). Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer. Thrombosis Research, 245, Article 109205. https://doi.org/10.1016/j.thromres.2024.109205

Background: Even though antithrombotic therapy (ATT) probably has little or even negative effect on the well-being of patients with cancer near the end of life, it is often continued until death, possibly leading to excess bleeding complications, inc... Read More about Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer.

Hospice topophilia and topophobia as experienced by a local population: Implications for equity of access (2024)
Journal Article
Bayley, Z., & Crowther, L. (2024). Hospice topophilia and topophobia as experienced by a local population: Implications for equity of access. Health and Place, 90, Article 103381. https://doi.org/10.1016/j.healthplace.2024.103381

The examination of hospice settings from the position of space and place is an emerging area of academic interest. Engaging with this perspective, this paper explores how topophilia and topophobia of the physical hospice setting coincides with and in... Read More about Hospice topophilia and topophobia as experienced by a local population: Implications for equity of access.

Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial. (2024)
Journal Article
Worthington, J., Soundy, A., Frost, J., Rooshenas, L., MacNeill, S. J., Realpe Rojas, A., Garfield, K., Liu, Y., Alloway, K., Ben-Shlomo, Y., Burns, A., Chilcot, J., Darling, J., Davies, S., Farrington, K., Gibson, A., Husbands, S., Huxtable, R., McNally, H., Murphy, E., …Caskey, F. J. (2024). Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial. Trials, 25(1), Article 688. https://doi.org/10.1186/s13063-024-08509-8

Background: Chronic kidney disease (CKD) prevalence is steadily increasing, in part due to increased multimorbidity in our aging global population. When progression to kidney failure cannot be avoided, people need unbiased information to inform decis... Read More about Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial..

'It's that gut feeling isn't it': General Practitioner experiences of safeguarding in care homes for older people (2024)
Journal Article
White, C., & Alton, E. (2024). 'It's that gut feeling isn't it': General Practitioner experiences of safeguarding in care homes for older people. The journal of adult protection, 26(6), 265-278. https://doi.org/10.1108/JAP-02-2024-0009

Purpose: General Practitioners (GPs) play an important role in adult safeguarding. However, their experiences of this role have received scant attention in the UK and internationally. This study explored their experiences of safeguarding within care... Read More about 'It's that gut feeling isn't it': General Practitioner experiences of safeguarding in care homes for older people.

Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B) (2024)
Journal Article
Higginson, I. J., Brown, S. T., Oluyase, A. O., May, P., Maddocks, M., Costantini, M., Bajwah, S., Normand, C., Bausewein, C., Simon, S. T., Ryan, K., Currow, D. C., Johnson, M., Hart, S. P., Mather, H., Krajnik, M., Tanzi, S., Ghirotto, L., Bolton, C., Janowiak, P., …Brown, J. M. (2024). Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B). Lancet, 12(10), 763-774. https://doi.org/10.1016/S2213-2600%2824%2900187-5

Background
Breathlessness frequently becomes severe among people with respiratory disease. Mirtazapine, a widely used antidepressant, showed promise. We determined the effectiveness of mirtazapine to alleviate severe persisting breathlessness.
Meth... Read More about Mirtazapine to alleviate severe breathlessness in patients with COPD or ILD: an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial (BETTER-B).

Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study (2024)
Journal Article
Jackson, C., Malia, C., Zacharias, H., Dyson, J., & Johnson, M. J. (2024). Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study. PLoS ONE, 19(9), Article e0310704. https://doi.org/10.1371/journal.pone.0310704

Objectives This study seeks to understand and address barriers to practitioners’ optimal assessment and management of people with delirium in hospices. Methods Retrospective clinical record review to identify areas of low concordance with guideline-a... Read More about Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study.

Destitute and dying: interventions and models of palliative and end of life care for homeless adults – a systematic review (2024)
Journal Article
Coverdale, M. R., & Murtagh, F. (2024). Destitute and dying: interventions and models of palliative and end of life care for homeless adults – a systematic review. BMJ Supportive & Palliative Care, 14(e3), e2411-e2422. https://doi.org/10.1136/spcare-2024-004883

Background Homeless adults experience a significant symptom burden when living with a life-limiting illness and nearing the end of life. This increases the inequalities that homeless adults face while coping with a loss of rootedness in the world. Th... Read More about Destitute and dying: interventions and models of palliative and end of life care for homeless adults – a systematic review.

Factors Influencing the Implementation of Digital Advance Care Planning: Qualitative Interview Study (2024)
Journal Article
Bradshaw, A., Birtwistle, J., Evans, C. J., Sleeman, K. E., Richards, S., Foy, R., Martin, P. M., Carder, P., Allsop, M. J., & Twiddy, M. (2024). Factors Influencing the Implementation of Digital Advance Care Planning: Qualitative Interview Study. Journal of medical Internet research, 26, Article e50217. https://doi.org/10.2196/50217

BACKGROUND: Palliative care aims to improve the quality of life for people with life-limiting illnesses. Advance care planning conversations that establish a patient's wishes and preferences for care are part of a person-centered approach. Internatio... Read More about Factors Influencing the Implementation of Digital Advance Care Planning: Qualitative Interview Study.

Why do acute healthcare staff behave unprofessionally towards each other and how can these behaviours be reduced? A realist review (2024)
Journal Article
Aunger, J. A., Abrams, R., Westbrook, J. I., Wright, J. M., Pearson, M., Jones, A., Mannion, R., & Maben, J. (2024). Why do acute healthcare staff behave unprofessionally towards each other and how can these behaviours be reduced? A realist review. Health and Social Care Delivery Research, 12(25), https://doi.org/10.3310/PAMV3758

Background: Unprofessional behaviour in healthcare systems can negatively impact staff well-being, patient safety and organisational costs. Unprofessional behaviour encompasses a range of behaviours, including incivility, microaggressions, harassment... Read More about Why do acute healthcare staff behave unprofessionally towards each other and how can these behaviours be reduced? A realist review.