Outputs (90)

Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process (2021)
Journal Article
Reedy, F., Pearson, M., Greenley, S., Clark, J., Currow, D. C., Bajwah, S., …Johnson, M. J. (in press). Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process. Palliative medicine, https://doi.org/10.1177/02692163211032114

Background: In combination with non-pharmacological interventions, opioids may safely reduce chronic breathlessness in patients with severe illness. However, implementation in clinical practice varies. Aim: To synthesise the published literature rega... Read More about Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process.

Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases (2021)
Journal Article
Barnes-Harris, M., Allingham, S., Morgan, D., Ferreira, D., Johnson, M. J., Eagar, K., & Currow, D. (2021). Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases. Thorax, 76(10), 989-995. https://doi.org/10.1136/thoraxjnl-2020-216039

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ. Background: Malignant and non-malignant respiratory diseases account for >4.6 million deaths annually worldwide. Despite similar symptom burd... Read More about Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases.

Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study (2021)
Journal Article
Genberg, J., Davies, J. M., Ahmadi, Z., Currow, D., Johnson, M. J., Tanash, H., …Ekström, M. (2021). Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study. ERJ Open Research, 7(1), 1-7. https://doi.org/10.1183/23120541.00716-2020

Background: Despite evidence that opioids might relieve chronic breathlessness, physicians may still be reluctant to prescribe them due to safety concerns. By contrast, benzodiazepine (BDZ) prescribing often seeks to reduce chronic breathlessness des... Read More about Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study.

A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study (2021)
Journal Article
Clark, J., Amoakwa, E., Wright-Hughes, A., Blenkinsopp, J., Currow, D. C., Meads, D., Farrin, A., Allgar, V., Macleod, U., & Johnson, M. (2021). A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study. PLoS ONE, 16(1), Article e0245647. https://doi.org/10.1371/journal.pone.0245647

Background People with cancer often have unidentified symptoms and social care needs. The Needs Assessment Tool-Cancer (NAT-C) is a validated, structured method of assessing patient/ carer concerns and prompting action, to address unmet need. Aims As... Read More about A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study.

A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol (2021)
Journal Article
Northgraves, M., Cohen, J., Allgar, V., Currow, D., Hart, S., Hird, K., Hodge, A., Johnson, M., Mason, S., Swan, F., & Hutchinson, A. (2021). A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol. ERJ Open Research, 7(1), Article 00955-2020. https://doi.org/10.1183/23120541.00955-2020

Introduction: Chronic breathlessness, persistent and disabling despite optimal treatment of underlying causes, is a prevalent and frightening symptom and is associated with many emergency presentations and admission to hospital. Breathlessness manage... Read More about A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol.

Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months: follow-up of a longitudinal clinical study (2020)
Journal Article
Ekström, M., Bornefalk, H., Sköld, C. M., Janson, C., Blomberg, A., Sandberg, J., Bornefalk-Hermansson, A., Currow, D. C., Johnson, M. J., & Sundh, J. (2021). Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months: follow-up of a longitudinal clinical study. European respiratory journal, 57(3), https://doi.org/10.1183/13993003.02823-2020

Chronic breathlessness is a dominating symptom that restricts daily life for many people with cardiorespiratory disease [1]. Different dimensions of the symptom, such as the intensity, sensory qualities (SQs) and emotional responses, can be assessed... Read More about Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months: follow-up of a longitudinal clinical study.

Prevalence and risk factors of breathlessness across Canada: A national retrospective cohort study in home care and nursing home populations (2020)
Journal Article
Seow, H., Dutta, P., Johnson, M. J., McMillan, K., Guthrie, D. M., Costa, A., & Currow, D. C. (in press). Prevalence and risk factors of breathlessness across Canada: A national retrospective cohort study in home care and nursing home populations. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2020.11.034

© 2020 American Academy of Hospice and Palliative Medicine Context: Breathlessness is a symptom associated with poor clinical outcomes and prognosis. Little is known about its long-term trends and associations with social factors including decline in... Read More about Prevalence and risk factors of breathlessness across Canada: A national retrospective cohort study in home care and nursing home populations.

Morphine for the symptomatic reduction of chronic breathlessness: the case for controlled release (2020)
Journal Article
Currow, D. C., Kochovska, S., Ferreira, D., & Johnson, M. (2020). Morphine for the symptomatic reduction of chronic breathlessness: the case for controlled release. Current opinion in supportive and palliative care, 14(3), 177-181. https://doi.org/10.1097/SPC.0000000000000520

Purpose of Review:
Clinicians who seek to reduce the symptomatic burden of chronic breathlessness by initiating regular low dose morphine have the choice of immediate or sustained release formulations - which will be better for this often frail popu... Read More about Morphine for the symptomatic reduction of chronic breathlessness: the case for controlled release.

Activities forgone because of chronic breathlessness: a cross-sectional, population prevalence study (2020)
Journal Article
Kochovska, S., Chang, S., Morgan, D. D., Ferreira, D., Sidhu, M., Saleh Moussa, R., Johnson, M. J., Ekström, M., & Currow, D. C. (2020). Activities forgone because of chronic breathlessness: a cross-sectional, population prevalence study. Palliative Medicine Reports, 1(1), 166-170. https://doi.org/10.1089/pmr.2020.0083

Background
Chronic breathlessness is a prevalent, disabling syndrome affecting many people for years. Identifying the impact of chronic breathlessness on people’s activities in the general population is pivotal for designing symptom management strat... Read More about Activities forgone because of chronic breathlessness: a cross-sectional, population prevalence study.

Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness (2020)
Journal Article
Ekström, M., Johnson, M. J., Huang, C., & Currow, D. C. (2020). Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness. European respiratory journal, 56(2), Article 1902202. https://doi.org/10.1183/13993003.02202-2019

Copyright ©ERS 2020. BACKGROUND: Chronic breathlessness has devastating consequences. The minimal clinically important difference (MCID) for current intensity has been estimated as 9 mm on a 100-mm visual analogue scale (VAS). We aimed to determine M... Read More about Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness.