Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review
Baddeley, Elin; Mann, Mala; Bravington, Alison; Johnson, Miriam J.; Currow, David; Murtagh, Fliss E.M.; Boland, Elaine; Obita, George; Oliver, Alfred; Seddon, Kathy; Nelson, Annmarie; Boland, Jason W.; Noble, Simon
Dr Alison Bravington A.Bravington@hull.ac.uk
Professor Miriam Johnson Miriam.Johnson@hull.ac.uk
Professor Fliss Murtagh F.Murtagh@hull.ac.uk
Professor of Palliative Care
Jason W. Boland
Background: Malignant bowel obstruction occurs in up to 50% of people with advanced ovarian and 15% of people with gastrointestinal cancers. Evaluation and comparison of interventions to manage symptoms are hampered by inconsistent evaluations of efficacy and lack of agreed core outcomes. The patient perspective is rarely incorporated. Aim: To synthesise the qualitative data regarding patient, caregiver and healthcare professionals’ views and experience of malignant bowel obstruction to inform the development of a core outcome set for the evaluation of malignant bowel obstruction. Design: A qualitative systematic review was conducted, with narrative synthesis. The review protocol was registered prospectively (https://www.crd.york.ac.uk/prospero, CRD42020176393). Data sources: MEDLINE, EMBASE, CINAHL, PsycINFO and Scopus databases were searched for studies published between 2010 and 2021. Reference lists were screened for further relevant publications, and citation tracking was performed. Results: Nine papers were included, reporting on seven studies which described the views and experiences of malignant bowel obstruction through the perspectives of 75 patients, 13 caregivers and 62 healthcare professionals. Themes across the papers included symptom burden, diverse experiences of interventions, impact on patient quality of life, implications and trajectory of malignant bowel obstruction, mixed experience of communication and the importance of realistic goals of care. Conclusion: Some of the most devastating sequelae of malignant bowel obstruction, such as pain and psychological distress, are not included routinely in its clinical or research evaluation. These data will contribute to a wider body of work to ensure the patient and caregiver perspective is recognised in the development of a core outcome set.
Baddeley, E., Mann, M., Bravington, A., Johnson, M. J., Currow, D., Murtagh, F. E., …Noble, S. (in press). Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review. Palliative medicine, https://doi.org/10.1177/02692163221081331
|Journal Article Type||Review|
|Acceptance Date||Feb 3, 2022|
|Online Publication Date||Mar 8, 2022|
|Deposit Date||Apr 25, 2022|
|Publicly Available Date||Oct 27, 2022|
|Peer Reviewed||Peer Reviewed|
|Keywords||Malignant bowel obstruction; Qualitative research; Palliative care; Systematic review; Intestinal obstruction; Gastric outlet obstruction; Cancer; Neoplasms|
Publisher Licence URL
© The Author(s) 2022.
https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
You might also like
Integration of oncology and palliative care: a Lancet Oncology Commission