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Outputs (49)

Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations (2017)
Journal Article
Webster, L., Groskreutz, D., Grinbergs-Saull, A., Howard, R., O’Brien, J. T., Mountain, G., Banerjee, S., Woods, B., Perneczky, R., Lafortune, L., Roberts, C., McCleery, J., Pickett, J., Bunn, F., Challis, D., Charlesworth, G., Featherstone, K., Fox, C., Goodman, C., Jones, R., …Livingston, G. (2017). Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations. Health Technology Assessment, 21(26), 1-192. https://doi.org/10.3310/hta21260

Background: There is currently no disease-modifying treatment available to halt or delay the progression of the disease pathology in dementia. An agreed core set of the best-available and most appropriate outcomes for disease modification would facil... Read More about Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations.

Qualitative analysis of how patients decide that they want risk-reducing mastectomy, and the implications for surgeons in responding to emotionally-motivated patient requests (2017)
Journal Article
Brown, S. L., Whiting, D., Fielden, H. G., Saini, P., Beesley, H., Holcombe, C., Holcombe, S., Greenhalgh, L., Fairburn, L., & Salmon, P. (2017). Qualitative analysis of how patients decide that they want risk-reducing mastectomy, and the implications for surgeons in responding to emotionally-motivated patient requests. PLoS ONE, 12(5), e0178392. https://doi.org/10.1371/journal.pone.0178392

Objective: Contemporary approaches to medical decision-making advise that clinicians should respect patients' decisions. However, patients' decisions are often shaped by heuristics, such as being guided by emotion, rather than by objective risk and b... Read More about Qualitative analysis of how patients decide that they want risk-reducing mastectomy, and the implications for surgeons in responding to emotionally-motivated patient requests.

Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review (2017)
Journal Article
Hussain, J. A., Johnson, M. J., Currow, D. C., White, I. R., Currow, D., Hussain, J., Johnson, M., Bland, M., Langan, D., & White, I. (2017). Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review. Journal of clinical epidemiology, 88, 81-91. https://doi.org/10.1016/j.jclinepi.2017.05.009

Objectives Assess (i) the quality of reporting and handling of missing data (MD) in palliative care trials, (ii) whether there are differences in the reporting of criteria specified by the Consolidated Standards of Reporting Trials (CONSORT) 2010 sta... Read More about Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review.

How many people will need palliative care in 2040? Past trends, future projections and implications for services (2017)
Journal Article
Etkind, S. N., Bone, A. E., Gomes, B., Lovell, N., Evans, C. J., Higginson, I. J., & Murtagh, F. E. M. (2017). How many people will need palliative care in 2040? Past trends, future projections and implications for services. BMC medicine, 15(1), https://doi.org/10.1186/s12916-017-0860-2

Background: Current estimates suggest that approximately 75% of people approaching the end-of-life may benefit
from palliative care. The growing numbers of older people and increasing prevalence of chronic illness in many
countries mean that more peo... Read More about How many people will need palliative care in 2040? Past trends, future projections and implications for services.

Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study (2017)
Journal Article
Kane, P. M., Murtagh, F. E., Ryan, K. R., Brice, M., Mahon, N. G., McAdam, B., McQuillan, R., O’Gara, G., Raleigh, C., Tracey, C., Howley, C., Higginson, I. J., Daveson, B. A., & on behalf of BuildCARE. (2018). Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study. Palliative medicine, 32(2), 517-524. https://doi.org/10.1177/0269216317706426

Background:
Recruitment challenges contribute to the paucity of palliative care research with advanced chronic heart failure patients.

Aim:
To describe the challenges and outline strategies of recruiting advanced chronic heart failure patients.

Des... Read More about Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study.

Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness (2017)
Journal Article
Johnson, M. J., Yorke, J., Hansen-Flaschen, J., Lansing, R., Ekström, M., Similowski, T., & Currow, D. (2017). Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness. European respiratory journal, 49(5), Article 1602277. https://doi.org/10.1183/13993003.02277-2016

Copyright ©ERS 2017. Breathlessness that persists despite treatment for the underlying conditions is debilitating. Identifying this discrete entity as a clinical syndrome should raise awareness amongst patients, clinicians, service providers, researc... Read More about Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness.

What influences the presentation of patients with chronic breathlessness to the Emergency Department? A mixed methods study (2017)
Thesis
Hutchinson, A. What influences the presentation of patients with chronic breathlessness to the Emergency Department? A mixed methods study. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/497045

Background: Chronic breathlessness is a common and distressing symptom of many long-term cardiorespiratory conditions and cancers which are highly prevalent in both the UK and worldwide. It is associated with presentation to the emergency department... Read More about What influences the presentation of patients with chronic breathlessness to the Emergency Department? A mixed methods study.

A systematic review of the effectiveness of palliative interventions to treat rectal tenesmus in cancer (2017)
Journal Article
Ní Laoire, Á., Fettes, L., & Murtagh, F. E. (2017). A systematic review of the effectiveness of palliative interventions to treat rectal tenesmus in cancer. Palliative medicine, 31(10), 975-981. https://doi.org/10.1177/0269216317697897

Background:
Rectal tenesmus is a distressing symptom in patients with advanced cancer and challenging to treat. There is lack of consensus on the appropriate management of tenesmus in this patient population.

Aim:
To identify and examine the effecti... Read More about A systematic review of the effectiveness of palliative interventions to treat rectal tenesmus in cancer.

Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups (2017)
Journal Article
Currow, D. C., Johnson, M. J., Dal Grande, E., Ekström, M., Ferreira, D., & McCaffrey, N. (2017). Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups. Thorax, 72(12), 1151-1153. https://doi.org/10.1136/thoraxjnl-2016-209908

© 2017 Published by the BMJ Publishing Group Limited. Little is known about the impact of chronic breathlessness (modified Medical Research Council (mMRC) score ≥2 for most days, at least three of the last six months) on health-related quality of lif... Read More about Chronic breathlessness associated with poorer physical and mental health-related quality of life (SF-12) across all adult age groups.