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Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema

Shoaib, Ahmad; Mamas, Mamas A; Ahmad, Qazi S; McDonagh, Theresa M; Hardman, Susanna MC; Rashid, Muhammad; Butler, Robert; Duckett, Simon; Satchithananda, Duwarakan; Nolan, James; Dargie, Henry; Clark, Andrew L; Cleland, John G F


Ahmad Shoaib

Mamas A Mamas

Qazi S Ahmad

Theresa M McDonagh

Susanna MC Hardman

Muhammad Rashid

Robert Butler

Simon Duckett

Duwarakan Satchithananda

James Nolan

Henry Dargie

Andrew L Clark

John G F Cleland


Most trials of patients hospitalized for heart failure focus on breathlessness (alveolar pulmonary oedema) but worsening peripheral oedema is also an important presentation. We investigated the relationship between the severity of peripheral oedema on admission and outcome amongst patients with a primary discharge death or diagnosis of heart failure.

We tested the hypothesis that severity of peripheral oedema is associated with length of hospital stay and mortality.

Patient variables reported to the National Heart Failure Audit for England & Wales between April 2008 and March 2013 were included in this analysis. Peripheral oedema was classified as ‘none’, ‘mild’, ‘moderate’ or ‘severe’. Length of stay, mortality during the index admission and for up to three years after discharge are reported.


Shoaib, A., Mamas, M. A., Ahmad, Q. S., McDonagh, T. M., Hardman, S. M., Rashid, M., …Cleland, J. G. F. (2019). Characteristics and outcome of acute heart failure patients according to the severity of peripheral oedema. International journal of cardiology, 285, 40-46.

Journal Article Type Article
Acceptance Date Mar 11, 2019
Online Publication Date Mar 15, 2019
Publication Date Jun 15, 2019
Deposit Date Mar 14, 2019
Publicly Available Date Mar 16, 2020
Print ISSN 0167-5273
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 285
Pages 40-46
Keywords Acute heart failure; Peripheral oedema; Breathlessness; Mortality
Public URL
Publisher URL
Additional Information This is the accepted manuscript of an article published in International Journal of Cardiology, 2019. The version of record is available at the DOI link in this record.


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