Shahla Korani
Therapeutic effects of Crocin in autoimmune diseases: A review
Korani, Shahla; Korani, Mitra; Sathyapalan, Thozhukat; Sahebkar, Amirhossein
Authors
Mitra Korani
Professor Thozhukat Sathyapalan T.Sathyapalan@hull.ac.uk
Professor of Diabetes, Endocrinology and Metabolism
Amirhossein Sahebkar
Abstract
The immune system when acts against selfmolecules results in an imbalance in immunologic tolerance leading to the development of several autoimmune diseases (ADs) such as rheumatoid arthritis, asthma, ulcerative colitis, type 1 diabetes, and multiple sclerosis. Improved recognition of the mechanisms of ADs has led to the advancement of the management of these diseases. The principal mediators of ADs are inflammatory molecules. The herbal medicines due to their antioxidant and antiinflammatory properties have an important role in the management of ADs. Crocin is the principal chemical component extracted from saffron, which is a medicinal plant. This review focuses on the therapeutic effects of Crocin in various ADs.
Citation
Korani, S., Korani, M., Sathyapalan, T., & Sahebkar, A. (2019). Therapeutic effects of Crocin in autoimmune diseases: A review. BioFactors, 45(6), 835-843. https://doi.org/10.1002/biof.1557
Journal Article Type | Article |
---|---|
Acceptance Date | Aug 5, 2019 |
Online Publication Date | Aug 20, 2019 |
Publication Date | 2019-11 |
Deposit Date | Aug 21, 2019 |
Publicly Available Date | Aug 21, 2020 |
Journal | BioFactors |
Print ISSN | 0951-6433 |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
Volume | 45 |
Issue | 6 |
Pages | 835-843 |
DOI | https://doi.org/10.1002/biof.1557 |
Keywords | Clinical Biochemistry; Molecular Medicine; Biochemistry; General Medicine |
Public URL | https://hull-repository.worktribe.com/output/2494237 |
Publisher URL | https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/biof.1557 |
Additional Information | Received: 2019-06-15; Accepted: 2019-08-05; Published: 2019-08-20 |
Contract Date | Aug 21, 2019 |
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Copyright Statement
©2019 The authors
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