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Therapeutic effects of Crocin in autoimmune diseases: A review

Korani, Shahla; Korani, Mitra; Sathyapalan, Thozhukat; Sahebkar, Amirhossein

Authors

Shahla Korani

Mitra Korani

Amirhossein Sahebkar



Abstract

The immune system when acts against selfmolecules results in an imbalance in immunologic tolerance leading to the development of several autoimmune diseases (ADs) such as rheumatoid arthritis, asthma, ulcerative colitis, type 1 diabetes, and multiple sclerosis. Improved recognition of the mechanisms of ADs has led to the advancement of the management of these diseases. The principal mediators of ADs are inflammatory molecules. The herbal medicines due to their antioxidant and antiinflammatory properties have an important role in the management of ADs. Crocin is the principal chemical component extracted from saffron, which is a medicinal plant. This review focuses on the therapeutic effects of Crocin in various ADs.

Citation

Korani, S., Korani, M., Sathyapalan, T., & Sahebkar, A. (2019). Therapeutic effects of Crocin in autoimmune diseases: A review. BioFactors, 45(6), 835-843. https://doi.org/10.1002/biof.1557

Journal Article Type Article
Acceptance Date Aug 5, 2019
Online Publication Date Aug 20, 2019
Publication Date 2019-11
Deposit Date Aug 21, 2019
Publicly Available Date Aug 21, 2020
Journal BioFactors
Print ISSN 0951-6433
Electronic ISSN 1872-8081
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 45
Issue 6
Pages 835-843
DOI https://doi.org/10.1002/biof.1557
Keywords Clinical Biochemistry; Molecular Medicine; Biochemistry; General Medicine
Public URL https://hull-repository.worktribe.com/output/2494237
Publisher URL https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/biof.1557
Additional Information Received: 2019-06-15; Accepted: 2019-08-05; Published: 2019-08-20

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