Nanophase Hydroxyapatite as a biomaterial in advanced hard tissue engineering: A review

Zakaria, Siti Maisurah; Sharif Zein, Sharif Hussein; Othman, Mohd. Roslee; Yang, Fang; Jansen, John A.

Abstract

Hydroxyapatite is a biocompatible material that is extensively used in the replacement and regeneration of bone material. In nature, nanostructured hydroxyapatite is the main component present in hard body tissues. Hence, the state of the art in nanotechnology can be exploited to synthesize nanophase hydroxyapatite that has similar properties with natural hydroxyapatite. Sustainable methods to mass-produce synthetic hydroxyapatite nanoparticles are being developed to meet the increasing demand for these materials and to further develop the progress made in hard tissue regeneration, especially for orthopedic and dental applications. This article reviews the current developments in nanophase hydroxyapatite through various manufacturing techniques and modifications.

Citation

Zakaria, S. M., Sharif Zein, S. H., Othman, M. R., Yang, F., & Jansen, J. A. (2013). Nanophase Hydroxyapatite as a biomaterial in advanced hard tissue engineering: A review. Tissue Engineering: Parts A, B, and C, 19(5), 431-441. https://doi.org/10.1089/ten.teb.2012.0624

• Journal Article Type: Review
• Online Publication Date: Apr 4, 2013
• Publication Date: 2013-10
• Deposit Date: Jul 7, 2020
• Journal: Tissue Engineering - Part B: Reviews
• Print ISSN: 1937-3368
• Publisher: Mary Ann Liebert
• Peer Reviewed: Peer Reviewed
• Volume: 19
• Issue: 5
• Pages: 431-441
• DOI: https://doi.org/10.1089/ten.teb.2012.0624
• Keywords: Biochemistry; Bioengineering; Biomaterials; Biomedical Engineering
• Public URL: https://hull-repository.worktribe.com/output/3536920