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Association Between Breastfeeding and the Development of Childhood Diabetes Mellitus Type I (DM I): The Effect of Prolonged Exclusive Breastfeeding on Gut Microbiome and the Link with DM I

Karagkouni, Iliana; Sideridou, Maria; Stoupi, Stavroula; Efthimiou, Georgios

Authors

Iliana Karagkouni

Maria Sideridou

Stavroula Stoupi



Abstract

The role of breastfeeding and dietary habits was studied in 10 children with DM I (case group) and compared with 10 healthy controls. Our results showed that the case group had significantly shorter exclusive breastfeeding duration compared with the control group (p = 0.006). An in silico comparative analysis of gut microbiota data from two recent studies was also performed in order to identify any specific bacterial genera potentially associated with DM I, due to prolonged breastfeeding. The Pasteurellaceae family, found in breast milk, was shown to have a significantly higher population in the intestine in the control group (p = 0.010). Overall, this preliminary study showed that exclusive breastfeeding duration is strongly associated with DM I. An association between breast milk microbiome and gut microbiome was also observed. This should encourage further research, aiming to examine both the effect of breastfeeding on gut microbiome and the possible links with DM I.

Citation

Karagkouni, I., Sideridou, M., Stoupi, S., & Efthimiou, G. (2021). Association Between Breastfeeding and the Development of Childhood Diabetes Mellitus Type I (DM I): The Effect of Prolonged Exclusive Breastfeeding on Gut Microbiome and the Link with DM I. Acta scientific paediatrics, 4(1), 28-32

Journal Article Type Review
Acceptance Date Dec 3, 2020
Online Publication Date Dec 29, 2020
Publication Date Jan 1, 2021
Deposit Date Feb 12, 2021
Publicly Available Date Feb 15, 2021
Journal Acta Scientific Paediatrics
Print ISSN 2581-883X
Publisher Acta Scientific
Peer Reviewed Peer Reviewed
Volume 4
Issue 1
Pages 28-32
Series ISSN 2581-883X
Keywords Diabetes mellitus type I; Breastfeeding; Gut microbiota
Public URL https://hull-repository.worktribe.com/output/3718228
Publisher URL https://actascientific.com/ASPE/ASPE-04-0338.php

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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/

Copyright Statement
Copyright: © 2021 Georgios Efthimiou., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.





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