The Immune Response and Effectiveness of COVID-19 Therapies

Tavasolian, Fataneh; Hatam, Gholam Reza; Mosawi, Sayed Hussain; Saadi, Mahdiyar Iravani; Abdollahi, Elham; Jamialahmadi, Tannaz; Sathyapalan, Thozhukat; Sahebkar, Amirhossein

Abstract

© 2021, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG. Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly pathogenic with relatively high mortality and morbidity. In addition to pneumonia, acute respiratory distress syndrome, and microembolic disorder, a high proportion of patients with SARS-CoV-2 develop lymphopenia and cytokine storm disorder. This review explores the underlying mechanisms behind the pathogenesis of SARS-CoV-2, especially the immune mechanisms, which could be potentially used as therapeutic targets for the management of COVID-19.

Citation

Tavasolian, F., Hatam, G. R., Mosawi, S. H., Saadi, M. I., Abdollahi, E., Jamialahmadi, T., Sathyapalan, T., & Sahebkar, A. (2021). The Immune Response and Effectiveness of COVID-19 Therapies. In P. C. Guest (Ed.), Clinical, Biological and Molecular Aspects of COVID-19 (115-126). Springer. https://doi.org/10.1007/978-3-030-59261-5_10

• Online Publication Date: Mar 4, 2021
• Publication Date: Mar 4, 2021
• Deposit Date: May 15, 2021
• Publicly Available Date: Mar 5, 2023
• Publisher: Springer
• Pages: 115-126
• Series Title: Advances in Experimental Medicine and Biology
• Series Number: 1321
• Book Title: Clinical, Biological and Molecular Aspects of COVID-19
• ISBN: 9783030592608
• DOI: https://doi.org/10.1007/978-3-030-59261-5_10
• Keywords: COVID-19; Cytokine storm syndrome; Immune response; Lymphopenia
• Public URL: https://hull-repository.worktribe.com/output/3742756
• Publisher URL: https://link.springer.com/chapter/10.1007%2F978-3-030-59261-5_10