A highly selective turn-on fluorescent probe for the detection of zinc

Shen, Ling Yi; Chen, Xiao Li; Yang, Xian Jiong; Xu, Hong; Huang, Ya Li; Zhang, Xing; Redshaw, Carl; Zhang, Qi Long

Abstract

A novel turn-on fluorescence probe L has been designed that exhibits high selectivity and sensitivity with a detection limit of 9.53 × 10−8 mol/L for the quantification of Zn2+ .1H-NMR spectroscopy and single crystal X-ray diffraction analysis revealed the unsymmetrical nature of the structure of the Schiff base probe L. An emission titration experiment in the presence of different molar fractions of Zn2+ was used to perform a Job’s plot analysis. The results showed that the stoichiometric ratio of the complex formed by L and Zn2+ was 1:1. Moreover, the molecular structure of the mononuclear Cu complex reveals one ligand L coordinates with one Cu atom in the asymmetric unit. On adding CuCl2 to the ZnCl2/L system, a Cu-Zn complex was formed and a strong quenching behavior was observed, which inferred that the Cu2+ displaced Zn2+ to coordinate with the imine nitrogen atoms and hydroxyl oxygen atoms of probe L.

Citation

Shen, L. Y., Chen, X. L., Yang, X. J., Xu, H., Huang, Y. L., Zhang, X., …Zhang, Q. L. (2021). A highly selective turn-on fluorescent probe for the detection of zinc. Molecules, 26(13), Article 3825. https://doi.org/10.3390/molecules26133825

• Journal Article Type: Article
• Acceptance Date: Jun 19, 2021
• Online Publication Date: Jun 23, 2021
• Publication Date: Jul 1, 2021
• Deposit Date: Jun 23, 2021
• Publicly Available Date: Jun 24, 2021
• Journal: Molecules
• Electronic ISSN: 1420-3049
• Publisher: MDPI
• Peer Reviewed: Peer Reviewed
• Volume: 26
• Issue: 13
• Article Number: 3825
• DOI: https://doi.org/10.3390/molecules26133825
• Keywords: Fluorescent probe; Schiff base; Crystal structure; Titration experiments
• Public URL: https://hull-repository.worktribe.com/output/3793048