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The Nereid on the rise: Platynereis as a model system

Özpolat, B. Duygu; Randel, Nadine; Williams, Elizabeth A.; Bezares-Calderón, Luis Alberto; Andreatta, Gabriele; Balavoine, Guillaume; Bertucci, Paola Y.; Ferrier, David E.K.; Gambi, Maria Cristina; Gazave, Eve; Handberg-Thorsager, Mette; Hardege, Jörg; Hird, Cameron; Hsieh, Yu Wen; Hui, Jerome; Mutemi, Kevin Nzumbi; Schneider, Stephan Q.; Simakov, Oleg; Vergara, Hernando M.; Vervoort, Michel; Jékely, Gáspár; Tessmar-Raible, Kristin; Raible, Florian; Arendt, Detlev

Authors

B. Duygu Özpolat

Nadine Randel

Elizabeth A. Williams

Luis Alberto Bezares-Calderón

Gabriele Andreatta

Guillaume Balavoine

Paola Y. Bertucci

David E.K. Ferrier

Maria Cristina Gambi

Eve Gazave

Mette Handberg-Thorsager

Cameron Hird

Yu Wen Hsieh

Jerome Hui

Kevin Nzumbi Mutemi

Stephan Q. Schneider

Oleg Simakov

Hernando M. Vergara

Michel Vervoort

Gáspár Jékely

Kristin Tessmar-Raible

Florian Raible

Detlev Arendt



Abstract

The Nereid Platynereis dumerilii (Audouin and Milne Edwards (Annales des Sciences Naturelles 1:195–269, 1833) is a marine annelid that belongs to the Nereididae, a family of errant polychaete worms. The Nereid shows a pelago-benthic life cycle: as a general characteristic for the superphylum of Lophotrochozoa/Spiralia, it has spirally cleaving embryos developing into swimming trochophore larvae. The larvae then metamorphose into benthic worms living in self-spun tubes on macroalgae. Platynereis is used as a model for genetics, regeneration, reproduction biology, development, evolution, chronobiology, neurobiology, ecology, ecotoxicology, and most recently also for connectomics and single-cell genomics. Research on the Nereid started with studies on eye development and spiralian embryogenesis in the nineteenth and early twentieth centuries. Transitioning into the molecular era, Platynereis research focused on posterior growth and regeneration, neuroendocrinology, circadian and lunar cycles, fertilization, and oocyte maturation. Other work covered segmentation, photoreceptors and other sensory cells, nephridia, and population dynamics. Most recently, the unique advantages of the Nereid young worm for whole-body volume electron microscopy and single-cell sequencing became apparent, enabling the tracing of all neurons in its rope-ladder-like central nervous system, and the construction of multimodal cellular atlases. Here, we provide an overview of current topics and methodologies for P. dumerilii, with the aim of stimulating further interest into our unique model and expanding the active and vibrant Platynereis community.

Citation

Özpolat, B. D., Randel, N., Williams, E. A., Bezares-Calderón, L. A., Andreatta, G., Balavoine, G., …Arendt, D. (2021). The Nereid on the rise: Platynereis as a model system. EvoDevo, 12(1), Article 10. https://doi.org/10.1186/s13227-021-00180-3

Journal Article Type Review
Acceptance Date Aug 20, 2021
Online Publication Date Sep 27, 2021
Publication Date Dec 1, 2021
Deposit Date Feb 25, 2022
Publicly Available Date Oct 27, 2022
Journal EvoDevo
Electronic ISSN 2041-9139
Publisher BioMed Central
Peer Reviewed Peer Reviewed
Volume 12
Issue 1
Article Number 10
DOI https://doi.org/10.1186/s13227-021-00180-3
Keywords Annelida; Spiralia; Marine model species; Evo-devo; Integrative biology
Public URL https://hull-repository.worktribe.com/output/3850163

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Copyright Statement
© The Author(s) 2021.
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.



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