Tethered ruthenium(II) η6-arene complexes: assessing the potential of benzylic substituents to control metal-centred chirality, and applications in asymmetric transfer hydrogenations of ketones

Shroot, Stephanie; Prior, Timothy J.; Wiles, Charlotte; Murray, Benjamin S

Abstract

The synthesis and characterisation of a small series of tethered ruthenium(II) η6-arene complexes is described, where a single benzylic substituent is examined as a route to enforcing chirality at the metal centre upon ligation of a tethered bidentate ligand. The application of these complexes as catalysts in the asymmetric transfer hydrogenation of ketones is described, with moderate enantioselectivities confirming the validity of the approach.

Citation

Shroot, S., Prior, T. J., Wiles, C., & Murray, B. S. (2022). Tethered ruthenium(II) η6-arene complexes: assessing the potential of benzylic substituents to control metal-centred chirality, and applications in asymmetric transfer hydrogenations of ketones. Journal of organometallic chemistry, 960, Article 122232. https://doi.org/10.1016/j.jorganchem.2021.122232

• Journal Article Type: Article
• Acceptance Date: Dec 22, 2021
• Online Publication Date: Dec 25, 2021
• Publication Date: Feb 15, 2022
• Deposit Date: Jan 6, 2022
• Publicly Available Date: Dec 26, 2022
• Journal: Journal of Organometallic Chemistry
• Print ISSN: 0022-328X
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 960
• Article Number: 122232
• DOI: https://doi.org/10.1016/j.jorganchem.2021.122232
• Keywords: Chiral-at-metal; Ruthenium; Asymmetric transfer hydrogenation; Half-sandwich complexes
• Public URL: https://hull-repository.worktribe.com/output/3905561
• Additional Information: This article is maintained by: Elsevier; Article Title: Tethered ruthenium(II) η6-arene complexes: assessing the potential of benzylic substituents to control metal-centred chirality, and applications in asymmetric transfer hydrogenations of ketones; Journal Title: Journal of Organometallic Chemistry; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.jorganchem.2021.122232; Content Type: article; Copyright: © 2021 Elsevier B.V. All rights reserved.