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Production of deuterium labelled (−)-epicatechin in a microreactor

Peng, Wei Min; Betts, Jonathan W.; Kitney, Stuart P.; Fu, Yiton; Peng, Wei-Min; Kelly, Stephen M.; Haswell, Stephen J.

Authors

Wei Min Peng

Jonathan W. Betts

Stuart P. Kitney

Yiton Fu

Wei-Min Peng

Stephen J. Haswell



Abstract

Green tea catechins have been reported to have multiple health benefits. To understand their metabolic and toxicological interactions in the human body studies need to be undertaken using stable isotope labelled compounds, but they can be time consuming and expensive. Using microreactor technology labelling catechins could be produced more quickly and at a reduced cost. This research reports on a 2-step synthesis of deuterium labelled epicatechin developed using microreactor technology for the production.

Citation

Betts, J. W., Kitney, S. P., Fu, Y., Peng, W., Kelly, S. M., & Haswell, S. J. (2011). Production of deuterium labelled (−)-epicatechin in a microreactor. Chemical Engineering Journal, 167(2-3), 545-547. https://doi.org/10.1016/j.cej.2010.08.093

Journal Article Type Article
Acceptance Date Aug 31, 2010
Online Publication Date Oct 23, 2010
Publication Date Mar 1, 2011
Journal CHEMICAL ENGINEERING JOURNAL
Print ISSN 1385-8947
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 167
Issue 2-3
Pages 545-547
DOI https://doi.org/10.1016/j.cej.2010.08.093
Keywords Microreactor; Epicatechin; Polyphenols; Deuterium; Labelling
Public URL https://hull-repository.worktribe.com/output/396321
Publisher URL https://www.sciencedirect.com/science/article/pii/S1385894710010053?via%3Dihub